ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
3. Inhibitors
Tupichilignan A
Citing Use of our Products
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
| Size /Price /Stock |
10 mM * 1 mL in DMSO / Inquiry |
Other Packaging |
*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap |
More articles cited ChemFaces products.
Phytomedicine.2022, 96:153877.J. Soc. Cosmet. Sci. Korea...2021...Phytother Res.2020, 34(4):788-795.PLoS One.2017, 12(8):e0181191Oxid Med Cell Longev2020, 12Oxid Med Cell Longev2019, 9056845:13Nutrients.2020, 12(5):1242.Biomedicines.2021, 9(8):996.
J Neuroinflammation.2020, 17(1):75.Toxicol Res.2019, 35(4):371-387Jour. of Stored Pro & Postharvest...2016...Appl. Sci.2021, 11(1),14.Korean J. Food Preserv. ...2021...Food Sci Biotechnol....2016...Anticancer Res.2021, 41(3):1357-1364.Anesth Pain Med (Seoul)....2020...
Arch Toxicol.2017, 91(10):3225-3245Molecules.2019, 24(20):3755Current Topics in Nutraceutical R...2021...Toxins (Basel).2019, 11(10):E575Food and Agriculture Org. Of the ...2019...Cell Death Differ.2021, 1-8.British Jou. Med.&Med. Research...2014...
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Our products had been exported to the following research institutions and universities, And still growing.
Subang Jaya Medical Centre (Malaysia)Chang Gung University (Taiwan)Mendel University in Brno (Czech Republic)Universite de Lille1 (France)
Florida A&M University (USA)Sri Sai Aditya Institute of Pha... (India)Anna University (India)Chungnam National University (Korea)
Leibniz Institute of Plant Bioc... (Germany)Universidade da Beira Interior (Germany)Korea Food Research Institute(K... (Korea)
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Tupichilignan A
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manager@chemfaces.com
Technical Inquiries:
service@chemfaces.com
Tel:
+86-27-84237783
Fax:
+86-27-84254680
Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Pathogens.2018, 7(3):E62Korean J. of Horticultural Sci. & Tech. 2017, 793-804Biofactors.2018, 44(2):168-179Exp Neurobiol.2018, 27(3):200-209Evid Based Complement Alternat Med.2021, 2021:5023536.Cell Death Dis.2019, 10(12):882Asian Pac J Cancer Prev.2021, 22(S1):97-106.Sci Rep.2019, 9:19059Foods.2021, 10(6):1378.Front Pharmacol.2021, 12:762829.
Related Screening Libraries
| Size /Price /Stock |
10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
|
Related Libraries |
Lignans Compound Library |
| Description: |
Reference standards. |
Tupichilignan A Description
| Source: |
The barks of Pseudolarix kaemp |
| Solvent: |
Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| Storage: |
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
|
| After receiving: |
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling. |
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
2.4851 mL |
12.4254 mL |
24.8509 mL |
49.7018 mL |
62.1272 mL |
| 5 mM |
0.497 mL |
2.4851 mL |
4.9702 mL |
9.9404 mL |
12.4254 mL |
| 10 mM |
0.2485 mL |
1.2425 mL |
2.4851 mL |
4.9702 mL |
6.2127 mL |
| 50 mM |
0.0497 mL |
0.2485 mL |
0.497 mL |
0.994 mL |
1.2425 mL |
| 100 mM |
0.0249 mL |
0.1243 mL |
0.2485 mL |
0.497 mL |
0.6213 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
| Structure Identification: |
| Asian Journal of Organic Chemistry, 2017,6(8). | | First asymmetric total synthesis of tupichilignan A using donor‐acceptor cyclopropanes: a structural revision of tupichilignan A.[Reference: WebLink] |
METHODS AND RESULTS:
The first asymmetric total synthesis of Tupichilignan A was achieved using enantioenriched donor-acceptor cyclopropanes. The key steps include an asymmetric cyclopropanation using the Hayashi-Jørgensen catalyst, an oxy-homo-Michael reaction of a bicyclic D-A cyclopropane, an α-benzylation of a γ-lactone, a decarboxylation to furnish a trans-α,β−dibenzyl-γ-lactone, a configurational inversion of a hydroxy chiral center via oxidation, and a final reduction, all of which occur with high stereoselectivity.
CONCLUSIONS:
The spectral data of the diastereomer previously identified in the literature as Tupichilignan A were found to be inconsistent with the reported data for the natural product. On the basis of the spectral data of both synthesized diastereomers, the structure of Tupichilignan A was revised and the absolute configuration of the 7-position of Tupichilignan A was changed from R to S. |
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