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    Natural Products
    Wulignan A1
    Wulignan A1
    Information
    CAS No. 117047-76-4 Price $288 / 5mg
    Catalog No.CFN99005Purity>=98%
    Molecular Weight342.4Type of CompoundLignans
    FormulaC20H22O5Physical DescriptionPowder
    Download Manual    COA    MSDS    SDFSimilar structuralComparison (Web)  (SDF)
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    Tel: (0086)-27-84237683
    Fax: (0086)-27-84254680
    E-mail: manager@chemfaces.com
    Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
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    Delivery & Payment method

    1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

    2. We accept: Wire transfer & Credit card & Paypal & Western Union
    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / $244.8 / In-stock
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
    Our products had been exported to the following research institutions and universities, And still growing.
  • University of Wuerzburg (Germany)
  • Wageningen University (Netherlands)
  • Universita' Degli Studi Di Cagl... (Italy)
  • Sri Sai Aditya Institute of Pha... (India)
  • Institute of Chinese Materia Me... (China)
  • Yale University (USA)
  • Fraunhofer-Institut für Moleku... (Germany)
  • Amity University (India)
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  • Regional Crop Research Institute (Korea)
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  • Package
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    Wulignan A1

    Wulignan A1
    Product Name Wulignan A1
    CAS No.: 117047-76-4
    Catalog No.: CFN99005
    Molecular Formula: C20H22O5
    Molecular Weight: 342.4 g/mol
    Purity: >=98%
    Type of Compound: Lignans
    Physical Desc.: Powder
    Targets: Antifection
    Source: The stems of Schisandra henryi.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Price: $288 / 5mg
    Inquire / Order: manager@chemfaces.com
    Technical Inquiries: service@chemfaces.com
    Tel: +86-27-84237783
    Fax: +86-27-84254680

    Address:
    1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
  • Saudi Pharm J2020, 10.1016
  • Arch Pharm Res.2015, 38(6):1080-9
  • Exp Biol Med (Maywood).2019, 244(16):1463-1474
  • J Ethnopharmacol.2020, 249:112396
  • Mol Cells.2015, 38(9):765-72
  • Antioxidants (Basel).2020, 9(6):544.
  • Free Radic Biol Med.2016, 97:307-319
  • Viruses.2017, 9(10)
  • Korean J. Crop Sci.2018, 63(2):131-139
  • Exp Ther Med.2019, 18(6):4388-4396
  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
  • Antiviral Compound Library
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  • Biological Activity
    Description: Wulignan A1 exhibits activity against leukemia P-388 in vitro; it also may have anti-influenza virus H1N1 and H1N1-TR (a Tamiflu drug resistant virus strain) activities.
    Targets: Antifection
    In vitro:
    Acta Chimica Sinica,1988, 46(5):483-8.
    Studies on the Constituents of Schisandra Henryi Ⅴ. The Structures of Wulignan A1, A2, Epiwulignan A1 and Epischisandrone)[Reference: WebLink]

    METHODS AND RESULTS:
    Four new lignan compounds named Wulignan A1 (4), A_2(5), epiWulignan A1 (6) and epischisandrone(7), and three known lignan compounds, enshicine(1), epienshicine(2) and schisandrone(3), were isolated from the fruits of Schisandra henryi Clarke collected in the district of Yibin, Sichuan Province.
    CONCLUSIONS:
    In anticancer screening all the four new compounds exhibit the activity against leukemia P-388 in vitro. Wulignan A1(4),
    US 8414938 B2[P]. 2013.
    Schisandrae fructus extracts for inhibition or prevention of H1N1 influenza virus infection and its application thereof[Reference: WebLink]
    Disclosed are an Schisandrae fructus extract for inhibition or prevention of influenza and its application, wherein the Schisandrae fructus extract is obtained by water, methanol, or ethanol extraction process and the extract comprises compounds such as schisandrone, benzoylgomisin P, Wulignan A1, epigomisin O, epiWulignan A1, and tigloylgomisin P. The extracts and purified compounds of Schisandrae fructus has anti-influenza virus H1N1 and H1N1-TR (a Tamiflu drug resistant virus strain) activities, therefore the extracts and the purified compounds of Schisandrae fructus can be applied as an inhitibory agent of a pharmaceutical composition for treatment or prevention agent for influenza infection.
    Wulignan A1 Description
    Source: The stems of Schisandra henryi.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Cell. 2018 Jan 11;172(1-2):249-261.e12.
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    IF=36.216(2019)

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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.9206 mL 14.6028 mL 29.2056 mL 58.4112 mL 73.014 mL
    5 mM 0.5841 mL 2.9206 mL 5.8411 mL 11.6822 mL 14.6028 mL
    10 mM 0.2921 mL 1.4603 mL 2.9206 mL 5.8411 mL 7.3014 mL
    50 mM 0.0584 mL 0.2921 mL 0.5841 mL 1.1682 mL 1.4603 mL
    100 mM 0.0292 mL 0.146 mL 0.2921 mL 0.5841 mL 0.7301 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    Chem Pharm Bull (Tokyo). 2009 Apr;57(4):405-7.
    Two new lignans from Schisandra henryi.[Pubmed: 19336937]

    METHODS AND RESULTS:
    Two new lignans, henricines A (1) and B (2), were isolated along with the eight known lignans, ganshisandrine (3), wulignan A2 (4), epiwulignan A(1) (5), deoxyschisandrin (6), Wulignan A1 (7), epischisandrone (8), schisantherin A (9), and schisandrol A (10), from the stems of Schisandra henryi.
    CONCLUSIONS:
    The structures of the new compounds were elucidated based on the spectral analysis, including 1D and 2D NMR experiments.
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