ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
3. Inhibitors
Xanthone
Citing Use of our Products
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
| Size /Price /Stock |
10 mM * 1 mL in DMSO / $7.0 / In-stock |
Other Packaging |
*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap |
More articles cited ChemFaces products.
Korean J. of Food Sci. and Tech...2016...Int J Mol Sci.2017, 18(5)Processes 2021, 9(5),894.Int J Mol Sci.2015, 16(8):18396-411Food Chem.2019, 279:80-87Korean Herb. Med. Inf....2020...Food Chem.2021, 377:131976. Chem Biol Interact.2019, 298:1-7
Front Pharmacol.2021, 12:744624.In Vitro Cellular & Developmental...2021...Int J Mol Sci.2021, 22(19):10220.Chemistr of plant2016, 2016021195Molecules.2019, 24(16):E2985Tea Res. Ins. Of China2017, 1-12J Agric Food Chem....2017...Environ Toxicol.2019, 34(12):1354-1362
Biomolecules.2021, 11(10):1537.Carbohydrate Polymer Technologies...2021...J Sci Food Agric.2021, Aug 21.Front Cell Dev Biol.2021, 9:638174. BMC Complement Altern Med....2017...Anal Bioanal Chem....2018...Indian J. of Experimental Bio....2020...
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Our products had been exported to the following research institutions and universities, And still growing.
University of Virginia (USA)Chungnam National University (Korea)Massachusetts General Hospital (USA)Wroclaw Medical University (Poland)
Semmelweis Unicersity (Hungary)Universidade Federal de Pernamb... (Brazil)Korea Intitute of Science and T... (Korea)University of Toulouse (France)
Universiti Sains Malaysia (Malaysia)Imperial College London (United Kingdom)University of Malaya (Malaysia)
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Xanthone
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manager@chemfaces.com
Technical Inquiries:
service@chemfaces.com
Tel:
+86-27-84237783
Fax:
+86-27-84254680
Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Biol Pharm Bull.2020, 43(10):1534-1541.Life (Basel).2021, 11(12):1399.Chin. Med.J.Res. Prac.2017, 31(4)Primary and Industrial.2018, 52(11)Processes2021, 9(11),2065.Cell Physiol Biochem.2017, 44(4):1381-1395Braz J Med Biol Res.2021, 54(12):e11183.Biochem Biophys Res Commun.2018, 495(1):1271-1277Iranian J. Pharm. Res.2021, 20(4):59-70Inflammation2015, 38(1):445-55
Related Screening Libraries
| Size /Price /Stock |
10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
|
Related Libraries |
Xanthones Compound Library |
| Description: |
Xanthone has antioxidant and anticorrosive properties, it performed excellently as a corrosion inhibitor for mild steel in sulphuric acid solution.
|
| In vitro: |
| Current Applied Physics, 2011, 11(3):382-392. | | Anti-corrosive properties of xanthone on mild steel corrosion in sulphuric acid: Experimental and theoretical investigations[Reference: WebLink] |
METHODS AND RESULTS:
The anti-corrosive effect of Xanthone (XAN) on the corrosion of mild steel in 0.5 M H2SO4 has been studied by gravimetric and UV–visible spectrophotometric methods at 303–333 K. Results obtained revealed that XAN performed excellently as a corrosion inhibitor for mild steel in sulphuric acid solution. Inhibition efficiency increases with increase in concentration of XAN but decreases with rise in temperature which is suggestive of physical adsorption mechanism although chemisorption may also play a part. Dubinin–Radushkevich adsorption isotherm model was found to adequately describe the adsorption of XAN onto the mild steel surface. Kinetic parameters of activation and thermodynamic parameters using the statistical model were calculated and discussed.
CONCLUSIONS:
The corrosion process in 0.5 M H2SO4 in the absence and presence of XAN follows first-order kinetics. The UV–visible absorption spectra of the solution containing the inhibitor after the immersion of mild steel specimen indicate the formation of a XAN–Fe complex. Quantum chemical calculations have been performed using DFT and several quantum chemical indices were calculated and correlated with the inhibitive effect. |
|
| In vivo: |
| J Agric Food Chem. 2009 Oct 14;57(19):8788-92 | | Bioavailability and antioxidant effects of a xanthone-rich Mangosteen (Garcinia mangostana) product in humans.[Pubmed: 19807152 ] | Oxidative damage is involved in many chronic diseases including those cited as the major causes of death in Western societies such as cardiovascular disorders and cancer. Antioxidants may prevent these degenerative processes by various mechanisms including the scavenging of free radicals. Intake of antioxidant supplements is associated with preventing oxidative damages.
METHODS AND RESULTS:
This study investigated the absorption and antioxidant effects of a Xanthone-rich mangosteen liquid in healthy human volunteers after the acute consumption of 59 mL of the supplement. The liquid contained mangosteen, aloe vera, green tea, and multivitamins. Results indicated that alpha-mangostin and vitamins B(2) and B(5) were bioavailable, with observed C(max) at t(max) of around 1 h. The antioxidant capacity measured with the oxygen radical absorbance capacity (ORAC) assay was increased with a maximum effect of 18% after 2 h, and the increased antioxidant level lasted at least 4 h.
CONCLUSIONS:
Overall, this study demonstrated the bioavailability of antioxidants from a Xanthone-rich mangosteen product and its in vivo antioxidant effects. |
|
Xanthone Description
| Source: |
The twigs of Calophyllum inophyllum |
| Solvent: |
Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| Storage: |
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
|
| After receiving: |
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling. |
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
5.0968 mL |
25.4842 mL |
50.9684 mL |
101.9368 mL |
127.421 mL |
| 5 mM |
1.0194 mL |
5.0968 mL |
10.1937 mL |
20.3874 mL |
25.4842 mL |
| 10 mM |
0.5097 mL |
2.5484 mL |
5.0968 mL |
10.1937 mL |
12.7421 mL |
| 50 mM |
0.1019 mL |
0.5097 mL |
1.0194 mL |
2.0387 mL |
2.5484 mL |
| 100 mM |
0.051 mL |
0.2548 mL |
0.5097 mL |
1.0194 mL |
1.2742 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
| Structure Identification: |
| Revue Canadienne De Chimie, 1963, 41(2):522-526. | | Cook D . INFRARED SPECTRA OF XANTHONE: LEWIS ACID COMPLEXES.[Reference: WebLink] |
METHODS AND RESULTS:
Xanthone, a member of the γ-pyrone species, which have basic carbonyl groups, forms an excellent series of solid complexes with Lewis acids. In these complexes the carbonyl oxygen atom is the donor site, and the carbonyl stretching vibration moves to progressively lower frequency as the Lewis acid strength increases. The carbonyl frequency in the BI3 complex, 1400 cm−1, is one of the lowest encountered in complexes of this type.
CONCLUSIONS:
The wide range of Lewis acids used to form these complexes has enabled a quantitative estimate of the Lewis acid strength to be made, which compares reasonably well with previous estimates. |
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