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    Natural Products
    Xanthone
    Xanthone
    Information
    CAS No. 90-47-1 Price $30 / 20mg
    Catalog No.CFN93355Purity>=98%
    Molecular Weight196.2Type of CompoundXanthones
    FormulaC13H8O2Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)  (SDF)
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    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / $7.0 / In-stock
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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    Xanthone

    Xanthone
    Product Name Xanthone
    CAS No.: 90-47-1
    Catalog No.: CFN93355
    Molecular Formula: C13H8O2
    Molecular Weight: 196.2 g/mol
    Purity: >=98%
    Type of Compound: Xanthones
    Physical Desc.: Powder
    Source: The twigs of Calophyllum inophyllum
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Price: $30 / 20mg
    Inquire / Order: manager@chemfaces.com
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  • Biol Pharm Bull.2020, 43(10):1534-1541.
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  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
  • Xanthones Compound Library
  • Biological Activity
    Description: Xanthone has antioxidant and anticorrosive properties, it performed excellently as a corrosion inhibitor for mild steel in sulphuric acid solution.
    In vitro:
    Current Applied Physics, 2011, 11(3):382-392.
    Anti-corrosive properties of xanthone on mild steel corrosion in sulphuric acid: Experimental and theoretical investigations[Reference: WebLink]

    METHODS AND RESULTS:
    The anti-corrosive effect of Xanthone (XAN) on the corrosion of mild steel in 0.5 M H2SO4 has been studied by gravimetric and UV–visible spectrophotometric methods at 303–333 K. Results obtained revealed that XAN performed excellently as a corrosion inhibitor for mild steel in sulphuric acid solution. Inhibition efficiency increases with increase in concentration of XAN but decreases with rise in temperature which is suggestive of physical adsorption mechanism although chemisorption may also play a part. Dubinin–Radushkevich adsorption isotherm model was found to adequately describe the adsorption of XAN onto the mild steel surface. Kinetic parameters of activation and thermodynamic parameters using the statistical model were calculated and discussed.
    CONCLUSIONS:
    The corrosion process in 0.5 M H2SO4 in the absence and presence of XAN follows first-order kinetics. The UV–visible absorption spectra of the solution containing the inhibitor after the immersion of mild steel specimen indicate the formation of a XAN–Fe complex. Quantum chemical calculations have been performed using DFT and several quantum chemical indices were calculated and correlated with the inhibitive effect.
    In vivo:
    J Agric Food Chem. 2009 Oct 14;57(19):8788-92
    Bioavailability and antioxidant effects of a xanthone-rich Mangosteen (Garcinia mangostana) product in humans.[Pubmed: 19807152 ]
    Oxidative damage is involved in many chronic diseases including those cited as the major causes of death in Western societies such as cardiovascular disorders and cancer. Antioxidants may prevent these degenerative processes by various mechanisms including the scavenging of free radicals. Intake of antioxidant supplements is associated with preventing oxidative damages.
    METHODS AND RESULTS:
    This study investigated the absorption and antioxidant effects of a Xanthone-rich mangosteen liquid in healthy human volunteers after the acute consumption of 59 mL of the supplement. The liquid contained mangosteen, aloe vera, green tea, and multivitamins. Results indicated that alpha-mangostin and vitamins B(2) and B(5) were bioavailable, with observed C(max) at t(max) of around 1 h. The antioxidant capacity measured with the oxygen radical absorbance capacity (ORAC) assay was increased with a maximum effect of 18% after 2 h, and the increased antioxidant level lasted at least 4 h.
    CONCLUSIONS:
    Overall, this study demonstrated the bioavailability of antioxidants from a Xanthone-rich mangosteen product and its in vivo antioxidant effects.
    Xanthone Description
    Source: The twigs of Calophyllum inophyllum
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 5.0968 mL 25.4842 mL 50.9684 mL 101.9368 mL 127.421 mL
    5 mM 1.0194 mL 5.0968 mL 10.1937 mL 20.3874 mL 25.4842 mL
    10 mM 0.5097 mL 2.5484 mL 5.0968 mL 10.1937 mL 12.7421 mL
    50 mM 0.1019 mL 0.5097 mL 1.0194 mL 2.0387 mL 2.5484 mL
    100 mM 0.051 mL 0.2548 mL 0.5097 mL 1.0194 mL 1.2742 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    Revue Canadienne De Chimie, 1963, 41(2):522-526.
    Cook D . INFRARED SPECTRA OF XANTHONE: LEWIS ACID COMPLEXES.[Reference: WebLink]

    METHODS AND RESULTS:
    Xanthone, a member of the γ-pyrone species, which have basic carbonyl groups, forms an excellent series of solid complexes with Lewis acids. In these complexes the carbonyl oxygen atom is the donor site, and the carbonyl stretching vibration moves to progressively lower frequency as the Lewis acid strength increases. The carbonyl frequency in the BI3 complex, 1400 cm−1, is one of the lowest encountered in complexes of this type.
    CONCLUSIONS:
    The wide range of Lewis acids used to form these complexes has enabled a quantitative estimate of the Lewis acid strength to be made, which compares reasonably well with previous estimates.
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