Info: Read More
  • Home
  • Natural Products
  • Bioactive
  • Screening Libraries
  • Hot Products
  • Plant Catalog
  • Customer Support
  • Product Use Citation
  • About Us
  • Contact Us
  • How to Order
  • Delivery time
  • Science | Nature | Cell | View More
    Natural Products
    Yadanzioside G
    Yadanzioside G
    Information
    CAS No. 95258-17-6 Price $413 / 5mg
    Catalog No.CFN96422Purity>=93%
    Molecular Weight768.76Type of CompoundDiterpenoids
    FormulaC36H48O18Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)  (SDF)
    Citing Use of our Products
    How to Order
    Orders via your E-mail:

    1. Product number / Name / CAS No.
    2. Delivery address
    3. Ordering/billing address
    4. Contact information
    Sent to Email: info@chemfaces.com
    Contact Us
    Order & Inquiry & Tech Support

    Tel: (0086)-27-84237683
    Fax: (0086)-27-84254680
    E-mail: manager@chemfaces.com
    Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
    Delivery time
    Delivery & Payment method

    1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

    2. We accept: Wire transfer & Credit card & Paypal & Western Union
    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / $598.9 / In-stock
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
    Our products had been exported to the following research institutions and universities, And still growing.
  • Medical University of Gdansk (Poland)
  • University of East Anglia (United Kingdom)
  • Seoul National University of Sc... (Korea)
  • Macau University of Science and... (China)
  • Utrecht University (Netherlands)
  • Charles University in Prague (Czech Republic)
  • University of Maryland School o... (USA)
  • Kyung Hee University (Korea)
  • Technical University of Denmark (Denmark)
  • Vin?a Institute of Nuclear Scie... (Serbia)
  • University of Zurich (Switzerland)
  • More...
  • Package
    Featured Products
    Bruceine D

    Catalog No: CFN90771
    CAS No: 21499-66-1
    Price: $258/20mg
    Isoacteoside

    Catalog No: CFN97049
    CAS No: 61303-13-7
    Price: $178/20mg
    Dihydrocucurbitacin B

    Catalog No: CFN92140
    CAS No: 13201-14-4
    Price: $318/10mg
    Moracin M

    Catalog No: CFN92327
    CAS No: 56317-21-6
    Price: $318/5mg
    Kurarinone

    Catalog No: CFN92003
    CAS No: 34981-26-5
    Price: $118/20mg
    Luteolin-7-O-glucoside

    Catalog No: CFN98565
    CAS No: 5373-11-5
    Price: $60/20mg
    Kushenol C

    Catalog No: CFN92391
    CAS No: 99119-73-0
    Price: $468/10mg

    Yadanzioside G

    Yadanzioside G
    Product Name Yadanzioside G
    CAS No.: 95258-17-6
    Catalog No.: CFN96422
    Molecular Formula: C36H48O18
    Molecular Weight: 768.76 g/mol
    Purity: >=93%
    Type of Compound: Diterpenoids
    Physical Desc.: Powder
    Source: The seeds of Brucea javanica.
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Price: $413 / 5mg
    Inquire / Order: manager@chemfaces.com
    Technical Inquiries: service@chemfaces.com
    Tel: +86-27-84237783
    Fax: +86-27-84254680

    Address:
    1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
  • Molecules.2019, 24(6):E1155
  • Plant Cell Physiol.2018, 59(1):128-141
  • Front Pharmacol.2021, 12:615157.
  • University of Central Lancashire2017, 20472
  • Industrial Crops and Products2017, 95:286-295
  • iScience.2020, 23(2):100849.
  • PLoS One.2021, 16(9):e0257243.
  • Int J Cosmet Sci.2019, 41(1):12-20
  • J Sci Food Agric.2018, 98(3):1153-1161
  • Front Plant Sci.2017, 8:723
  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
  • Antileukaemic Compound Library
  • Diterpenoids Compound Library
  • Biological Activity
    Description: Yadanzioside G has antileukemic activity.
    In vitro:
    Phytother Res. 2011 Dec;25(12):1796-800.
    Seven quassinoids from Fructus Bruceae with cytotoxic effects on pancreatic adenocarcinoma cell lines.[Pubmed: 21480411 ]
    Our previous studies showed that the alcohol extract of the fruit of Brucea javanica (Fructus Bruceae) possessed significant cytotoxicity in pancreatic adenocarcinoma cell lines.
    METHODS AND RESULTS:
    A bioassay-guided fractionation and purification resulted in the isolation and characterization of seven quassinoids including brusatol, bruceine D, bruceine H, yadanzioside A, Yadanzioside G, javanicoside C and bruceantinoside A. Among them, brusatol exhibited the most potent in vitro antipancreatic cancer action, with IC(50) values of 0.36 μm and 0.10 μm on PANC-1 and SW1990 cell lines, respectively.
    CONCLUSIONS:
    This is the first report on the antipancreatic adenocarcinoma activity of brusatol.
    Bull. Chem. Soc. Jpn.,1985, 58(9), 2680-6.
    Structures of new quassinoid glycosides, yadanziosides A,B,C,D,E,G,H, and new quassinoids, dehydrobrusatol and dehydrobruceantinol from Brucea javanica (L.) Merr.[Reference: WebLink]

    METHODS AND RESULTS:
    Quassinoid glycosides, yadanzioside A, yadanzioside B, yadanzioside C, yadanzioside D, yadanzioside E, Yadanzioside G, and yadanzioside H, and two quassinoids, dehydrobrusatol and dehydrobruceantinol were isolated from seeds of Brucea javanica, and their structures were determined.
    CONCLUSIONS:
    These glycosides showed bitter taste and were demonstrated to have antileukemic activity.
    Yadanzioside G Description
    Source: The seeds of Brucea javanica.
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
    ChemFaces New Products and Compounds
    Somnifericin

    Catalog No: CFN95280
    CAS No: 173693-57-7
    Price: $318/5mg
    Polygalin J

    Catalog No: CFN95175
    CAS No: N/A
    Price: $318/5mg
    Gymnoside III

    Catalog No: CFN95033
    CAS No: 899430-03-6
    Price: $318/10mg
    1-Methoxycarbonyl-beta-carboline-N...

    Catalog No: CFN95023
    CAS No: 74690-74-7
    Price: $318/5mg
    Tangshenoside I

    Catalog No: CFN95108
    CAS No: 117278-74-7
    Price: $218/5mg
    Chamigrenol

    Catalog No: CFN95247
    CAS No: 19822-80-1
    Price: $318/10mg
    Deoxy euphorbia factor L1

    Catalog No: CFN95340
    CAS No: 247099-01-0
    Price: $318/10mg
    (1S,2S)-threo-Honokitriol

    Catalog No: CFN95076
    CAS No: 1099687-80-5
    Price: $413/5mg
    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.3008 mL 6.504 mL 13.008 mL 26.0159 mL 32.5199 mL
    5 mM 0.2602 mL 1.3008 mL 2.6016 mL 5.2032 mL 6.504 mL
    10 mM 0.1301 mL 0.6504 mL 1.3008 mL 2.6016 mL 3.252 mL
    50 mM 0.026 mL 0.1301 mL 0.2602 mL 0.5203 mL 0.6504 mL
    100 mM 0.013 mL 0.065 mL 0.1301 mL 0.2602 mL 0.3252 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    Arch Pharm Res. 2011 Aug;34(8):1297-300.
    One new pregnane glycoside from the seeds of cultivated Brucea javanica.[Pubmed: 21910051 ]
    A new pregnane glycoside, named (20R)-O-(3)-β-D-glucopyranosyl-(1→2)-α-L-arabinopyranosyl-pregn-5-en-3β,20-diol (1), and seven known compounds, brusatol (2), bruceine B (3), bruceine D (4), yadanziolide A (5), bruceine E (6), Yadanzioside G (7), and yadanzioside B (8), were isolated from the cultivated dry seeds of Brucea javanica.
    METHODS AND RESULTS:
    The structure of 1 was elucidated on the basis of 1D- and 2D-NMR spectroscopic analyses. Their inhibitory effects on tumor cells were also tested. Compound 1 was slightly active against HL-60, SMMC-7721, A-549, and MCF-7 tumor cells. Compounds 2 and 3 demonstrated significant inhibitory activities against all tested cells.
    CONCLUSIONS:
    These results indicate that cultivated B. javanica could replace the wild plant as an antitumor plant resource
    Bruceine D

    Catalog No: CFN90771
    CAS No: 21499-66-1
    Price: $258/20mg
    Isoacteoside

    Catalog No: CFN97049
    CAS No: 61303-13-7
    Price: $178/20mg
    Dihydrocucurbitacin B

    Catalog No: CFN92140
    CAS No: 13201-14-4
    Price: $318/10mg
    Moracin M

    Catalog No: CFN92327
    CAS No: 56317-21-6
    Price: $318/5mg
    Kurarinone

    Catalog No: CFN92003
    CAS No: 34981-26-5
    Price: $118/20mg
    Luteolin-7-O-glucoside

    Catalog No: CFN98565
    CAS No: 5373-11-5
    Price: $60/20mg
    Kushenol C

    Catalog No: CFN92391
    CAS No: 99119-73-0
    Price: $468/10mg