(+)-alpha-Pinene | CAS:7785-70-8 | Manufacturer ChemFaces

(+)-alpha-Pinene

ChemFaces products have been cited in many studies from excellent and top scientific journals

Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC

How to Order

Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com

Delivery time

Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal

Citing Use of our Products

More Impact Factor than five Cite...

* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.

According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.

Size /Price /Stock	10 mM * 1 mL in DMSO / $7.0 / In-stock
Other Packaging	*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap

Featured Products

More...

N-p-trans-Coumaroyltyramine

Catalog No: CFN98494
CAS No: 36417-86-4
Price: $268/10mg

Butein

Catalog No: CFN98776
CAS No: 487-52-5
Price: $100/20mg

Isovitexin

Catalog No: CFN98620
CAS No: 38953-85-4
Price: $50/20mg

Dehydroglyasperin C

Catalog No: CFN96483
CAS No: 199331-35-6
Price: $ / mg

2-(3,4-Dihydroxyphenyl)ethanol

Catalog No: CFN99076
CAS No: 10597-60-1
Price: $88/20mg

1-Dehydro-6-gingerdione

Catalog No: CFN92298
CAS No: 76060-35-0
Price: $258/10mg

1-Caffeoylquinic acid

Catalog No: CFN99121
CAS No: 1241-87-8
Price: $350/10mg

Crategolic acid

Catalog No: CFN98669
CAS No: 4373-41-5
Price: $80/20mg

Eburicol

Catalog No: CFN97175
CAS No: 6890-88-6
Price: $ /

Ferulic acid

Catalog No: CFN99158
CAS No: 1135-24-6
Price: $40/20mg

Description:

alpha-Pinene has anti-cancer,and anti-inflammatory effects, it exerts the anti-inflammatory activity through the suppression of MAPKs and the NF-κB.

In vitro:

The American Journal of Chinese Medicine, 2015, 43(4):1-12.

Alpha-Pinene Exhibits Anti-Inflammatory Activity Through the Suppression of MAPKs and the NF-κB Pathway in Mouse Peritoneal Macrophages.[Reference: WebLink]

METHODS AND RESULTS:
In this study, we found that alpha-pinene (α-pinene) exhibits anti-inflammatory activity through the suppression of mitogen-activated protein kinases (MAPKs) and the nuclear factor-kappa B (NF-κB) pathway in mouse peritoneal macrophages. α-Pinene is found in the oils of many coniferous trees and rosemary. We investigated the inhibitory effects of α-Pinene on inflammatory responses induced by lipopolysaccharide (LPS) using mouse peritoneal macrophages. α-Pinene significantly decreased the LPS-induced production of interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), and nitric oxide (NO). α-Pinene also inhibited inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) expressions in LPS-stimulated macrophages. Additionally, the activations of MAPKs and NF-κB were attenuated by means of α-pinene treatment.
CONCLUSIONS:
These results indicate that α-pinene has an anti-inflammatory effect and that it is a potential candidate as a new drug to treat various inflammatory diseases.

(+)-alpha-Pinene Description

Source:	The herbs of Schinus terebintinfolius Raddi (Anacardiaceae)
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Structure Identification:

Journal of bacteriology,1987,169(11):4972-9.

Bacterial metabolism of alpha-pinene: pathway from alpha-pinene oxide to acyclic metabolites in Nocardia sp. strain P18.3.[Reference: WebLink]

METHODS AND RESULTS:
Over 20 gram-positive bacteria were isolated by elective culture with (+/-)-alpha-pinene((+)-alpha-Pinene/(-)-alpha-Pinene) as the sole carbon source. One of these strains, Nocardia sp. strain P18.3, was selected for detailed study. alpha-Pinene-grown cells oxidized, without lag, alpha-pinene, alpha-pinene oxide (epoxide), and the cis and trans isomers of 2-methyl-5-isopropylhexa-2,5-dienal. No other tested terpene was oxidized at a significant rate. alpha-Pinene was not metabolized by cell extracts in the presence or absence of NADH or NADPH. Cell extracts catalyzed a rapid decyclization of alpha-pinene oxide, in the absence of added cofactors, with the formation of cis-2-methyl-5-isopropylhexa-2,5-dienal. Further oxidation of the aldehyde to the corresponding acid occurred in the presence of NAD. Both activities were induced by growth with alpha-pinene.
CONCLUSIONS:
A rapid, nonenzymic transformation of the cis aldehyde into the trans isomer occurred in glycine buffer. The trans isomer was also a substrate for the NAD-linked aldehyde dehydrogenase. The distribution of the alpha-pinene oxide lyase in alpha-pinene-utilizing Pseudomonas spp. was also investigated and was compatible with the two alternative ring-cleavage sequences that have been proposed on the basis of accumulated metabolites.

Product Name	(+)-alpha-Pinene
Price:	$30 / 20mg
CAS No.:	7785-70-8
Catalog No.:	CFN70200
Molecular Formula:	C₁₀H₁₆
Molecular Weight:	136.2 g/mol
Purity:	>=98%
Type of Compound:	Monoterpenoids
Physical Desc.:	Oil
Source:	The herbs of Schinus terebintinfolius Raddi (Anacardiaceae)
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS
Similar structural:	Comparison
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Monoterpenoids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	7.3421 mL	36.7107 mL	73.4214 mL	146.8429 mL	183.5536 mL
5 mM	1.4684 mL	7.3421 mL	14.6843 mL	29.3686 mL	36.7107 mL
10 mM	0.7342 mL	3.6711 mL	7.3421 mL	14.6843 mL	18.3554 mL
50 mM	0.1468 mL	0.7342 mL	1.4684 mL	2.9369 mL	3.6711 mL
100 mM	0.0734 mL	0.3671 mL	0.7342 mL	1.4684 mL	1.8355 mL

CFN92931	1-Methoxymethyl-beta-carboline	55854-60-9	212.25	C₁₃H₁₂N₂O
CFN99640	Ginkgolide B	15291-77-7	424.4	C₂₀H₂₄O₁₀
CFN98827	Erythrartine	51666-26-3	329.4	C₁₉H₂₃NO₄
CFN92213	Kadsuric acid 3-methylester	1041070-16-9	484.7	C₃₁H₄₈O₄