Hot Products
| Catalog No. | Information |
| CFN90399 | Tanshinone IIA-sulfonic sodium Tanshinone IIA sulfonate (sodium) is a water-soluble derivative of tanshinone IIA, which acts as an inhibitor of store-operated Ca2+ entry (SOCE), and is used to treat cardiovascular disorders.Sodium tanshinone IIA sulfonate pretreatment reduces infarct size and improves cardiac function in an ischemia-reperfusion-induced rat myocardial injury model via activation of Akt/FOXO3A/Bim-mediated signal pathway. |
| CFN99820 | Tanshinone IIB Co-treatment with Tanshinone IIB (TSB) significantly inhibits the DNA laddering, cytotoxicity and apoptosis of rat cortical neurons induced by staurosporine in a concentration-dependent manner; TSB also suppresses the elevated Bax protein and decreased bcl-2 and caspase-3 proteins induced by staurosporine in rat cortical neurons; TSB is effective in reducing stroke-induced brain damage and may represent a novel drug candidate for further development. TSB significantly inhibits the uptake of digoxin and vinblastine in membrane vesicles containing PgP or MRP1, moderately stimulates PgP ATPase activity, suggesting TSB is a substrate for PgP and MRP1 and that drug resistance to TSB therapy and drug interactions may occur through PgP and MRP1 modulation. |
| CFN90543 | Tarasaponin VII Reference standards. |
| CFN99074 | Taraxasterol Taraxasterol has anti-inflammatory, anti- tumor-promoting , anti-endotoxic shock and anti-allergic asthma activities. It inhibited NO, IFN-γ, PGE(2), TNF-α, IL-1β and IL-6 production. |
| CFN97104 | Taraxasterol acetate Taraxasterol acetate has anti-inflammatory activity in bino rats against carrageenan, formaldehyde and adjuvant induced inflammations in doses between 10 and 100 mg/kg. Taraxasterol acetate also displays potential antibacterial activities. |
| CFN99381 | Taraxerol Taraxerol can be used as a lipid biomarker for mangrove input to the SE Atlantic. Taraxerol has potent anti-inflammatory effects,it downregulates the expression of proinflammatory mediators in macrophages by interfering with the activation of TAK1 and Akt, thus preventing NF-κB activation. Taraxerol also has anti-cancer activity, it shows inhibitory effects on AGS cell growth through inducing G2/M arrest and promotion of cell apoptosis, taraxeryl acetate has less effect on cell cycle arrest and apoptosis of AGS cells than taraxerol. |
| CFN98821 | Taraxerone Taraxerone has allelopathic and antifungal effects.Taraxerone prevents catalase, superoxide dismutase, and reduces glutathione concentrations from the decrease induced by ethanol administration with the concentration dependent manner. |
| CFN98087 | Taraxeryl acetate Taraxeryl acetate shows the significant antiviral activity against herpes simplex virus (type II). It has less effect on cell cycle arrest and apoptosis of AGS cells than taraxerol. A. roxburghiana has antidiabetic activity, could be attributed due to PTP1B inhibition by its triterpene constituents, betulin, betulinic acid and Taraxeryl acetate. |
| CFN93181 | Tartaric acid Tartaric acid, oxalic acid and histamine are the well-recognized pain-inducing agents in the stinging hairs of U. thunbergiana. |
| CFN90060 | Tartrazine Tartrazine is a food additive that belongs to a class of artificial dyes and contains an azo group; it has significant genotoxic effect , may be harmful to health and its prolonged use could trigger carcinogenesis. |
