Hot Products
| Catalog No. | Information |
| CFN99166 | Tetrandrine Tetrandrine is a calcium channel blocker, which shows antitumor, antifibrotic, anti-oxidant, anti-inflammatory and immunosuppressive activity. It suppressed Wnt/β-catenin signaling transduction, the migration of DU145 and PC-3 cells, EOMA cell growth through the ROS/Akt pathway and inhibited inward rectifying potassium current in cultured bovine aortic endothelial cells. |
| CFN99936 | Tetrodotoxin Tetrodotoxin, a poison from the puffer fish, at very low concentrations, blocks the action potential production through its selective inhibition of the sodium-carrying mechanism while keeping the potassium-carrying mechanism intact.Modulation of tetrodotoxin-resistant voltage-gated Na+ current (TTX-R INa) is a mechanism for sensitization of mammalian nociceptors. |
| CFN91786 | Thalifendine Thalifendine is a metabolite of Berberine, with antiplasmodial and antiamoebic activities. Thalifendine shows activities against P. falciparum and E. histolytica with IC50s of 7.91 μM and 116 μM, respectively. Thalifendine inhibited cytochrome P450 (CYP) 2D6. |
| CFN92336 | Thalifoline Thalifoline shows antifungal activity, with 100 ug against Fusarium oxysporum f. sp. lycopersici. |
| CFN98597 | Theaflavin Theaflavin is a suitable natural inhibitor against influenza A (H1N1) neuraminidase, which has anti-inflammatory, antioxidative, anti-mutagenic, anti-HSV-1, and anti-carcinogenic properties. Theaflavin is active in the prevention of fatty liver and obesity, it can significantly reduce lipid accumulation, suppress fatty acid synthesis, and stimulate fatty acid oxidation. Theaflavin inhibits LPS-Induced IL-6, MCP-1, and ICAM-1 expression in bone marrow-derived macrophages through the blockade of NF-κB and MAPK signaling pathways; it also protects nigral dopaminergic neurons against chronic MPTP/probenecid induced Parkinson's disease. |
| CFN99130 | Theaflavin 3,3'-di-O-gallate Theaflavin-3,3'-digallate(TF3), an inducer of oxidative stress, which has anti-inflammatory and cancer chemopreventive actions, it reduces tumor angiogenesis by downregulating HIF-1αand VEGF; suggests that TF3 might serve as a potential anti-angiogenic agent for cancer treatment. TF3 and lactic acid combinations can reduce Herpes Simplex Virus(HSV) infectivity. |
| CFN98599 | Theaflavin-3'-gallate Theaflavin-3'-gallate, acts as prooxidants and induces oxidative stress, with carcinoma cells more sensitive than normal fibroblasts. |
| CFN90170 | Theaflavin-3-gallate Theaflavin-3-gallate has anticancer and apoptotic effects in non-small cell lung carcinoma, it acts as prooxidants and induce oxidative stress, with carcinoma cells more sensitive than normal fibroblasts. Theaflavin-3-gallate can play a role in decreased intestinal cholesterol absorption via inhibition of micelle formation. |
| CFN98598 | Theaflavine-3,3'-digallate Theaflavin-3,3'-digallate is a potent AMP-activated protein kinase (AMPK) activator with anti-adiposity activity in adipocytes, suggesting its potential application in functional foods and nutraceuticals for obesity management. Theaflavin-3,3'-digallate is also an inducer of oxidative stress and apoptosis, it has strong antioxidant and antiangiogenic activities, it inhibits the tube formation of endothelial cells via decreased both MMP-2 and MMP-9 activities in vitro. A combination microbicide containing theaflavin-3,3'-digallate and lactic acid can reduce herpes simplex virus (HSV) transmission. Theaflavin-3,3'-digallate may exert its anti-inflammatory and cancer chemopreventive actions by suppressing the activation of NFkappaB through inhibition of IkappaB kinase (IKK) activity. Theaflavin-3,3'-digallate can repress osteoclastogenesis and prevent wear debris-induced osteolysis via suppression of ERK pathway, it is a promising candidate for the treatment of osteoclast-related osteolytic diseases, such as wear debris-induced peri-implant osteolysis (PIO). |
| CFN91689 | Theasaponin E1 Theasaponin E1 has antitumor, anti-inflammatory, QR-inducing activity and obesity prevention effects. Theasaponin E1 inhibits gastric emptying in mice and accelerates gastrointestinal transit. Theasaponin E1 destroys the salt tolerance of yeasts. Theasaponin E1 show antisweet activity. Theasaponin E1 has neuroprotective effects. |
