ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
Citing Use of our Products
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Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
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1. Usually delivery time: Next day delivery by 9:00 a.m. Order now
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / $256.0 / In-stock||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Int J Mol Sci.2015, 16(8):18396-411J Breast Cancer.2015, 18(2):112-118Am J Chin Med.2015, 30:1-22University of Limpopo2016, 1-237Analytical sci. & Tech2016, 186-193Anal Bioanal Chem. 2016, 408(15)PLoS One.2017, 12(3):e0173585Research on Crops.2017, 18(2)
Int J Mol Sci.2017, 19(1)J Ethnopharmacol.2017, 196:75-83Food Res Int.2017, 96:40-45Evid Based Complement Alternat Me...2018...RSC Adv.2018, 32621-32636Saf Health Work.2019, 10(2):196-204BMC Complement Altern Med....2019...Int J Mol Sci.2019, 20(8):E1855
Molecules.2019, 24(11):E2044Process Biochemistry2019, 85:106-115Neurochem Int.2020, 133:104629J Pharmaceut Biomed2020, 178:112894Molecules.2020, 25(20):4851.Acta Edulis Fungi2020, 27(02):63-76.Naunyn Schmiedebergs Arch Pharmac...2021...
Our products had been exported to the following research institutions and universities, And still growing.
Gyeongsang National University (Korea)FORTH-IMBB (Greece)Chulalongkorn University (Thailand)Universidad Miguel Hernández (Spain)
Sanford Burnham Medical Researc... (USA)Northeast Normal University Cha... (China)S.N.D.T. Women's University (India)Monash University Sunway Campus (Malaysia)
University of Pretoria (South Africa)Aveiro University (Portugal)Hamdard University (India)
Inquire / Order:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Clin Exp Pharmacol Physiol.2020, doi: 10.1111Molecules.2016, 21(10)J Sci Food Agric.2017, 97(5):1656-1662Appl. Sci.2020, 10(23), 8729J Agric Food Chem.2017, 65(13):2670-2676Natural Product Communications2020, doi: 10.1177.J of App. Res. on Med&Aromatic Plants2020, 100291.ACS Omega2020, 5,33,20825-20830Nat Prod Sci.2016, 22(2)Pharmacognosy Journal2019, 11(2): 369-373
Related Screening Libraries
|| Theaflavin-3'-gallate, acts as prooxidants and induces oxidative stress, with carcinoma cells more sensitive than normal fibroblasts.|
|Basic Clin Pharmacol Toxicol. 2008 Jul;103(1):66-74. |
|Theaflavin-3-gallate and theaflavin-3'-gallate, polyphenols in black tea with prooxidant properties.[Pubmed: 18346048]|
|This study compared the in vitro responses of human gingival fibroblasts and of carcinoma cells derived from the tongue to theaflavin-3-gallate (TF-2A) and Theaflavin-3'-gallate (TF-2B), polyphenols in black tea. |
METHODS AND RESULTS:
In a cell-free assay, TF-2A and Theaflavin-3'-gallate reacted directly with reduced glutathione (GSH), in a time- and concentration-dependent manner. Intracellular storages of GSH were depleted on treatment of the cells with the theaflavin monomers. Depletion of intracellular GSH was more extensive with TF-2A than with Theaflavin-3'-gallate and was more pronounced in the carcinoma, than in the normal, cells. The toxicities of the theaflavins were potentiated when the cells were cotreated with the GSH depleter, d,l-buthionine-[S,R]-sulfoximine. In the presence of catalase, pyruvate and divalent cobalt, all scavengers of reactive oxygen species, the cytotoxicities of the theaflavins were lessened. TF-2A and Theaflavin-3'-gallate induced lipid peroxidation in the carcinoma cells, whereas in the fibroblasts, peroxidation was evident upon exposure to TF-2A, but not to Theaflavin-3'-gallate.
These studies demonstrated that the black tea theaflavin monomers, TF-2A and Theaflavin-3'-gallate, act as prooxidants and induce oxidative stress, with carcinoma cells more sensitive than normal fibroblasts.
||The leaves of Camellia sinensis (L.) O. Kuntze.
||DMSO, Pyridine, Methanol, Ethanol, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.