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1-Hydroxytropacocaine
1-Hydroxytropacocaine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 1-Hydroxytropacocaine
Price:
CAS No.: 156497-23-3
Catalog No.: CFN00202
Molecular Formula: C15H19NO3
Molecular Weight: 261.32 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The leaves of Erythroxylum novogranatense var. novogranatense.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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Biological Activity
Description: Reference standards.
1-Hydroxytropacocaine Description
Source: The leaves of Erythroxylum novogranatense var. novogranatense.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.8267 mL 19.1336 mL 38.2673 mL 76.5345 mL 95.6681 mL
5 mM 0.7653 mL 3.8267 mL 7.6535 mL 15.3069 mL 19.1336 mL
10 mM 0.3827 mL 1.9134 mL 3.8267 mL 7.6535 mL 9.5668 mL
50 mM 0.0765 mL 0.3827 mL 0.7653 mL 1.5307 mL 1.9134 mL
100 mM 0.0383 mL 0.1913 mL 0.3827 mL 0.7653 mL 0.9567 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Phytochemistry,1994,36(2):357-360.
1-Hydroxytropacocaine: An abundant alkaloid of Erythroxylum novogranatense var. Novogranatense and var. Truxillense[Reference: WebLink]
A new alkaloid, 1-Hydroxytropacocaine, was isolated from leaves of greenhouse-cultivated Erythroxylum novogranatense var. novogranatense and identified.
METHODS AND RESULTS:
Quantitative levels of this alkaloid in dry leaf were similar to those for cocaine, i.e. 0.3–0.5% w/w. 1-Hydroxytropacocaine was also detected at 0.04–0.07% w/w (relative to dry coca leaf) in greenhouse-cultivated Erythroxylum novogranatense var. truxillense and at similar levels in Erythroxylum novogranatense var. novogranatense, grown at a tropical site other than in South America.
CONCLUSIONS:
The presence of 1-Hydroxytropacocaine was <0.01% w/w (relative to dry coca leaf) in suspected Erythroxylum novogranatense var. novogranatense and Erythroxylum coca var. coca, field-cultivated in Colombia and Bolivia, respectively.
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