• ChemFaces is a professional high-purity natural products manufacturer.
  • Product Intended Use
  • 1. Reference standards
  • 2. Pharmacological research
  • 3. Inhibitors
  • Home
  • Natural Products
  • Bioactive
  • Screening Libraries
  • Hot Products
  • Plant Catalog
  • Customer Support
  • Product Use Citation
  • About Us
  • Contact Us
  • Natural Products
    Baicalin
    Information
    CAS No. 21967-41-9 Price $50 / 20mg
    Catalog No.CFN99111Purity>=98%
    Molecular Weight446.37Type of CompoundFlavonoids
    FormulaC21H18O11Physical DescriptionYellow powder
    Download Manual    COA    MSDS    SDFSimilar structuralComparison (Web)
    How to Order
    Orders via your E-mail:

    1. Product number / Name / CAS No.
    2. Delivery address
    3. Ordering/billing address
    4. Contact information
    Sent to Email: info@chemfaces.com
    Contact Us
    Order & Inquiry & Tech Support

    Tel: (0086)-27-84237683
    Fax: (0086)-27-84254680
    E-mail: manager@chemfaces.com
    Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
    Delivery time
    Delivery & Payment method

    1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

    2. We accept: Wire transfer & Credit card & Paypal & Western Union
    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    Our products had been exported to the following research institutions and universities, And still growing.
  • Johannes Gutenberg University Ma... (Germany)
  • University of Cincinnati (USA)
  • University of Canterbury (New Zealand)
  • Copenhagen University (Denmark)
  • Universidad de Buenos Aires (Argentina)
  • Heinrich-Heine-University Düsse... (Germany)
  • Chiang Mai University (Thailand)
  • University of Amsterdam (Netherlands)
  • Universiti Kebangsaan Malaysia (Malaysia)
  • Sanford Burnham Medical Research... (USA)
  • University of Parma (Italy)
  • More...
  • Package
    Featured Products
    7-Methoxyneochamaejasmine A

    Catalog No: CFN92156
    CAS No: 402828-38-0
    Price: $433/5mg
    Isonemerosin

    Catalog No: CFN95008
    CAS No: 181524-79-8
    Price: $268/20mg
    Arteannuin B

    Catalog No: CFN98807
    CAS No: 50906-56-4
    Price: $308/20mg
    Rebaudioside B

    Catalog No: CFN90470
    CAS No: 58543-17-2
    Price: $463/5mg
    Acteoside

    Catalog No: CFN97048
    CAS No: 61276-17-3
    Price: $90/20mg
    Baicalin Description
    Source: The root of Scutellaria baicalensis Georgi
    Biological Activity or Inhibitors: 1. Baicalin has diuretic activity.
    2. Baicalin is a prolyl endopeptidase inhibitor, induces apoptosis in pancreatic cancer cells, and affects the GABA receptors.
    3. Baicalin can control TH17 cell differentiation and may be a promising therapeutic agent for the treatment of TH17 cells-mediated inflammatory diseases.
    Solvent: Pyridine, Methanol, Ethanol, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.2403 mL 11.2015 mL 22.4029 mL 44.8059 mL 56.0073 mL
    5 mM 0.4481 mL 2.2403 mL 4.4806 mL 8.9612 mL 11.2015 mL
    10 mM 0.224 mL 1.1201 mL 2.2403 mL 4.4806 mL 5.6007 mL
    50 mM 0.0448 mL 0.224 mL 0.4481 mL 0.8961 mL 1.1201 mL
    100 mM 0.0224 mL 0.112 mL 0.224 mL 0.4481 mL 0.5601 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Baicalin References Information
    Citation [1]

    BMB Rep. 2015 Mar 5. pii: 3111.

    Baicalin, baicalein and wogonin inhibits high glucose-induced vascular inflammation in vitro and in vivo.[Pubmed: 25739393]
    Data showed that HG induced markedly increased vascular permeability, monocyte adhesion, expressions of cell adhesion molecules (CAMs), formation of reactive oxygen species (ROS) and activation of nuclear factor (NF)-κB. Remarkably, all of the above mentioned vascular inflammatory effects of HG were attenuated by pretreatment with Baicalin, baicalein, and wogonin. Vascular inflammatory responses induced by HG are critical events underlying development of various diabetic complications, therefore, our results suggest that Baicalin, baicalein, and wogonin may have significant therapeutic benefits against diabetic complications and atherosclerosis.
    Citation [2]

    Inflammation. 2015 Jan 30.

    Baicalin Inhibits Lipopolysaccharide-Induced Inflammation Through Signaling NF-κB Pathway in HBE16 Airway Epithelial Cells.[Pubmed: 25630720]
    These findings suggest that the anti-inflammatory properties of Baicalin may be resulted from the inhibition of IL-6, IL-8, and TNF-α expression via preventing signaling NF-κB pathway in HBE16 airway epithelial cells. In addition, this study provides evidence to understand the therapeutic effects of Baicalin on inflammatory diseases in clinical practice.