ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
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More articles cited ChemFaces products.
Evidence-Based Complementary & Alternative Med.2017Food Science and Bio.31 October 2016Phytomedicine1 March 2018;Arch Pharm Res.2014 Oct 18.PLoS One. 2017 Aug 8;
New Zealand Journal of Forestry Sci.2014, 44:17Front Pharmacol. 2016 Nov 30J Agric Food Chem.2018 Jan 10;Sci Rep. 2016 Apr 27Clin Exp Pharmacol Physiol.2015 Aug 1
Phytochem Anal.2016 Sep;Nat Prod Sci.2016 Jun;22(2)Yakugaku Zasshi.2018 Jan 30;Phytomedicine.2018 Jan 1;
Our products had been exported to the following research institutions and universities, And still growing.
University of Maryland (USA)University of Cincinnati (USA)Yale University (USA)Julius Kühn-Institut (Germany)
University of Wisconsin-Madison (USA)Universit?t Basel (Switzerland)Universidad Miguel Hernández (Spain)Universidad de Antioquia (Colombia)
Helmholtz Zentrum München (Germany)Korea Intitute of Science and Te... (Korea)Cornell University (USA)
|| 6,7-Dihydroneridienone A exhibits notable leishmanicidal activity. |
|Planta Med 2012; 78 - PI239. |
|Compounds with antileishmanial activity isolated from the stems of Pentalinon andrieuxii.[Reference: WebLink]|
METHODS AND RESULTS:
Bioassay-guided fractionation was conducted on a chloroform-soluble extract of the stems of Pentalinon andrieuxii, a Mayan traditional antileishmanial plant collected in a rainforest region of Mexico, using a Leishmania (L.) mexicana strain of parasites. This led to the isolation of five C21 sterol derivatives, neridienone A (1), 6,7-Dihydroneridienone A (2), cybisterol (3), 12β-hydroxypregn-4-ene-3,20-dione (4), and pentalinonoside (5), two coumarins, fraxidin (6) and fraxetol (7), as well as betulinic acid (8) and (+)-pinoresinol (9).
All the isolates were evaluated in vitro for their ability to inhibit the growth of promastigotes of L. mexicana. Compounds 1-4, and 6 were found to exhibit notable leishmanicidal activity in this assay.
6,7-Dihydroneridienone A Description
||The herbs of Tithonia diversifolia
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.PMID: 29328914
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.PMID: 29149595
Scientific Reports 2017 Dec 11;7(1):17332.doi: 10.1038/s41598-017-17427-6.PMID: 29230013
Molecules. 2017 Oct 27;22(11). pii: E1829.doi: 10.3390/molecules22111829.PMID: 29077044
J Cell Biochem. 2018 Feb;119(2):2231-2239.doi: 10.1002/jcb.26385. PMID: 28857247
Phytomedicine. 2018 Feb 1;40:37-47. doi:10.1016/j.phymed.2017.12.030PMID: 29496173
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.