Science | Nature | Cell | View More
Natural Products
6,7-Dihydroneridienone A
6,7-Dihydroneridienone A
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 6,7-Dihydroneridienone A
Price:
CAS No.: 72959-46-7
Catalog No.: CFN96120
Molecular Formula: C21H28O3
Molecular Weight: 328.5 g/mol
Purity: >=98%
Type of Compound: Steroids
Physical Desc.: Powder
Source: The herbs of Tithonia diversifolia
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • University of Queensland (Australia)
  • University of Malaya (Malaysia)
  • Celltrion Chemical Research Ins... (Korea)
  • University of Pretoria (South Africa)
  • University of Illinois (USA)
  • Universidade de Franca (Brazil)
  • Sri Ramachandra University (India)
  • Universitas Airlangga (Indonesia)
  • The University of Newcastle (Australia)
  • MTT Agrifood Research Finland (Finland)
  • Leibniz-Institut für Pflanzenb... (Germany)
  • More...
Package
Featured Products
Amentoflavone

Catalog No: CFN99526
CAS No: 1617-53-4
Price: $40/20mg
Naringenin chalcone

Catalog No: CFN90606
CAS No: 73692-50-9
Price: $168/20mg
Trilobatin

Catalog No: CFN98658
CAS No: 4192-90-9
Price: $30/20mg
Angelicide

Catalog No: CFN93012
CAS No: 92935-94-9
Price: $ / mg
L-Leucine

Catalog No: CFN94811
CAS No: 61-90-5
Price: $30/20mg
Coronaridine

Catalog No: CFN92859
CAS No: 467-77-6
Price: $ / mg
Secologanic acid

Catalog No: CFN95028
CAS No: 60077-46-5
Price: $418/20mg
1-Deoxynojirimycin

Catalog No: CFN99933
CAS No: 19130-96-2
Price: $30/20mg
25S-Inokosterone

Catalog No: CFN93571
CAS No: 19595-18-7
Price: $318/10mg
L-Phenylalanine

Catalog No: CFN93152
CAS No: 63-91-2
Price: $30/20mg
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: 6,7-Dihydroneridienone A exhibits notable leishmanicidal activity.
Targets: Antifection
In vitro:
Planta Med 2012; 78 - PI239.
Compounds with antileishmanial activity isolated from the stems of Pentalinon andrieuxii.[Reference: WebLink]

METHODS AND RESULTS:
Bioassay-guided fractionation was conducted on a chloroform-soluble extract of the stems of Pentalinon andrieuxii, a Mayan traditional antileishmanial plant collected in a rainforest region of Mexico, using a Leishmania (L.) mexicana strain of parasites. This led to the isolation of five C21 sterol derivatives, neridienone A (1), 6,7-Dihydroneridienone A (2), cybisterol (3), 12β-hydroxypregn-4-ene-3,20-dione (4), and pentalinonoside (5), two coumarins, fraxidin (6) and fraxetol (7), as well as betulinic acid (8) and (+)-pinoresinol (9).
CONCLUSIONS:
All the isolates were evaluated in vitro for their ability to inhibit the growth of promastigotes of L. mexicana. Compounds 1-4, and 6 were found to exhibit notable leishmanicidal activity in this assay.
6,7-Dihydroneridienone A Description
Source: The herbs of Tithonia diversifolia
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Isomargaritene

Catalog No: CFN95304
CAS No: 64271-11-0
Price: $318/10mg
Lappaol A

Catalog No: CFN95067
CAS No: 62333-08-8
Price: $333/10mg
4-O-Caffeoyl-3-O-syringoylquinic a...

Catalog No: CFN95430
CAS No: 1207645-17-7
Price: $413/5mg
Scutellarein-7-O-glucoside

Catalog No: CFN95082
CAS No: 26046-94-6
Price: $318/5mg
Fortunellin-6''-beta-D-glucopyrano...

Catalog No: CFN95315
CAS No: 1218774-64-1
Price: $318/5mg
Euphorbia factor L24

Catalog No: CFN95334
CAS No: 1613700-13-2
Price: $318/5mg
Fragransin B1

Catalog No: CFN95443
CAS No: 112516-03-7
Price: $318/5mg
Planispine A

Catalog No: CFN95348
CAS No: 1202761-42-9
Price: $318/10mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.0441 mL 15.2207 mL 30.4414 mL 60.8828 mL 76.1035 mL
5 mM 0.6088 mL 3.0441 mL 6.0883 mL 12.1766 mL 15.2207 mL
10 mM 0.3044 mL 1.5221 mL 3.0441 mL 6.0883 mL 7.6104 mL
50 mM 0.0609 mL 0.3044 mL 0.6088 mL 1.2177 mL 1.5221 mL
100 mM 0.0304 mL 0.1522 mL 0.3044 mL 0.6088 mL 0.761 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Amentoflavone

Catalog No: CFN99526
CAS No: 1617-53-4
Price: $40/20mg
Naringenin chalcone

Catalog No: CFN90606
CAS No: 73692-50-9
Price: $168/20mg
Trilobatin

Catalog No: CFN98658
CAS No: 4192-90-9
Price: $30/20mg
Angelicide

Catalog No: CFN93012
CAS No: 92935-94-9
Price: $ / mg
L-Leucine

Catalog No: CFN94811
CAS No: 61-90-5
Price: $30/20mg
Coronaridine

Catalog No: CFN92859
CAS No: 467-77-6
Price: $ / mg
Secologanic acid

Catalog No: CFN95028
CAS No: 60077-46-5
Price: $418/20mg
1-Deoxynojirimycin

Catalog No: CFN99933
CAS No: 19130-96-2
Price: $30/20mg
25S-Inokosterone

Catalog No: CFN93571
CAS No: 19595-18-7
Price: $318/10mg
L-Phenylalanine

Catalog No: CFN93152
CAS No: 63-91-2
Price: $30/20mg
Tags: buy 6,7-Dihydroneridienone A | 6,7-Dihydroneridienone A supplier | purchase 6,7-Dihydroneridienone A | 6,7-Dihydroneridienone A cost | 6,7-Dihydroneridienone A manufacturer | order 6,7-Dihydroneridienone A | 6,7-Dihydroneridienone A distributor