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    8(17),12E,14-Labdatrien-20-oic acid
    8(17),12E,14-Labdatrien-20-oic acid
    Information
    CAS No. 1639257-36-5 Price
    Catalog No.CFN89102Purity>=98%
    Molecular Weight302.45Type of CompoundDiterpenoids
    FormulaC20H30O2Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)
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    Description: 8(17),12E,14-Labdatrien-20-oic acid is a natural product from Isodon yuennanensis.
    8(17),12E,14-Labdatrien-20-oic acid Description
    Source: The rhizomes of Isodon yuennanensis.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.3063 mL 16.5317 mL 33.0633 mL 66.1266 mL 82.6583 mL
    5 mM 0.6613 mL 3.3063 mL 6.6127 mL 13.2253 mL 16.5317 mL
    10 mM 0.3306 mL 1.6532 mL 3.3063 mL 6.6127 mL 8.2658 mL
    50 mM 0.0661 mL 0.3306 mL 0.6613 mL 1.3225 mL 1.6532 mL
    100 mM 0.0331 mL 0.1653 mL 0.3306 mL 0.6613 mL 0.8266 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    Nat Prod Res. 2015;29(7):628-32.
    Two new labdane diterpenoids from the rhizomes of Isodon yuennanensis.[Pubmed: 25420949 ]

    METHODS AND RESULTS:
    Two new labdane diterpenoids, s-trans-8(17),12E,14-Labdatrien-20-oic acid (1), s-trans-12E,14-Labdadien-20,8beta-olide (2), along with 10 known compounds, hinokiol (3), ursonic acid (4), 2α,3α-dihydroxyolean-12-en-28-oic acid (5), 2α,3β,23-trihydroxyolean-12-en-28-oic acid (6), ethyl 3-(3,4-dihydroxyphenyl)lactate (7), ethyl rosmarinate (8), (Z,E)-2-(3,4-dihydroxyphenyl)ethenyl caffeic ester (9), tridecanoic acid (10), β-sitosterol (11) and daucosterol (12), were isolated from the 70% acetone extract of the rhizomes of Isodon yuennanensis.
    CONCLUSIONS:
    Their structures were elucidated based on the analyses of extensive spectroscopic data and physicochemical properties.