|Source:||The root of Scutellaria baicalensis Georgi|
|Biological Activity or Inhibitors:|
|Solvent:||DMSO, Pyridine, Methanol, Ethanol, etc.|
|Storage:||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
|After receiving:||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.|
|1 mg||5 mg||10 mg||20 mg||25 mg|
|1 mM||2.1079 mL||10.5394 mL||21.0788 mL||42.1576 mL||52.697 mL|
|5 mM||0.4216 mL||2.1079 mL||4.2158 mL||8.4315 mL||10.5394 mL|
|10 mM||0.2108 mL||1.0539 mL||2.1079 mL||4.2158 mL||5.2697 mL|
|50 mM||0.0422 mL||0.2108 mL||0.4216 mL||0.8432 mL||1.0539 mL|
|100 mM||0.0211 mL||0.1054 mL||0.2108 mL||0.4216 mL||0.527 mL|
Nat Prod Res. 2014;28(20):1772-6.
|A new antioxidant flavone glycoside from Scutellaria baicalensis Georgi.[Pubmed: 24995563 ]|
|A new flavone glycoside, wogonin 7-O-β-D-ethylglucuronide (1), together with a new natural flavone glycoside baicalein 7-O-β-D-ethylglucuronide (Baicalein 7-O-beta-D-ethylglucuronide,2) and four known analogues, wogonoside (3), wogonin (4), oroxylin A 7-O-β-D-methylglucuronide (5) and oroxylin A (6), was isolated from the roots of Scutellaria baicalensis Georgi. The structure elucidation of the new compound was primarily based on HR-ESI-MS, 1D and 2D NMR analyses. Compounds 1 and 3 inhibited FeSO4-Cys-induced liver homogenate lipid peroxidation with IC50 at 18.2 μM and 24.9 μM, respectively, and exhibited strong cytoprotective effects against H2O2-induced oxidative damage in human umbilical vein endothelial cells at low concentrations of 10.0 μM and 3.0 μM.|
Journal of Applied Pharmaceutical Science, 2013, 3(12):46-51.
|Evaluation of wound healing activity of baicalein-7-O- β-Dglucuronide isolated from Leucas aspera[Reference: WebLink]|
|Leucas aspera (Willd.) Linn. (Lamiaceae), commonly known as "Thumbai," is distributed throughout India. This study includes the isolation and characterization of flavonoids present in Leucas aspera flowers were compared wound healing activity with standard soframycin ointment. The plant materials were extracted with 95% methanol, petroleum ether, ethyl acetate, and were subjected to column and TLC chromatographic separation analysis. The chemical constituents isolated from the flowers of L. aspera were characterized based on chemical tests and spectral analysis such as UV and NMR spectroscopy. The structure of the isolated compound was confirmed as baicalein-7-O- β-D-glucuronide (baicalin). It has been investigated for wound healing activity by applying on the albino rats. A slow rate of healing was observed earlier which turns to very rapid on the 12th day. The histopathological examination provided additional evidence for the experimental wound healing studies. Protease is a biochemical marker and pH measured to support the wound healing activity. We conclude that the baicalin isolated with the flowers of L. aspera has better wound healing activity.|