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    Cimigenol-3-one
    Information
    CAS No. 31222-32-9 Price
    Catalog No.CFN89138Purity>=98%
    Molecular Weight486.69Type of CompoundTriterpenoids
    FormulaC30H46O5Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)
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    Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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    Description: Cimigenol-3-one is a natural product from Calophyllum inophyllum.
    Cimigenol-3-one Description
    Source: The rhizomes of Cimicifuga dahurica.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

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    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.0547 mL 10.2735 mL 20.547 mL 41.0939 mL 51.3674 mL
    5 mM 0.4109 mL 2.0547 mL 4.1094 mL 8.2188 mL 10.2735 mL
    10 mM 0.2055 mL 1.0273 mL 2.0547 mL 4.1094 mL 5.1367 mL
    50 mM 0.0411 mL 0.2055 mL 0.4109 mL 0.8219 mL 1.0273 mL
    100 mM 0.0205 mL 0.1027 mL 0.2055 mL 0.4109 mL 0.5137 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    Journal of Yunnan University of Traditional Chinese Medicine, 2013, 36 (3) :31-35.
    Studies on Chemical Constituents of the Rhizomes of Cimicifuga dahurica.[Reference: WebLink]
    To study the major chemical constituents of the rhizomes of C.dahurica.
    METHODS AND RESULTS:
    Using silica gel,RP-18,Sephadex LH-20 and HPLC to isolate and purify compounds.The structures of isolated compounds were identified by extensive spectroscopic methods,including MS,NMR,and etc. Ten known compounds,ferulic acid(1),methyl-ferulic acid(2),3-methoxyl-4-ethyoxyl-phenylpropionic acid(3),peucenin(4),cimigeno(l5),Cimigenol-3-one(6),25-O-methyl-cimigenol(7),25-O-acetyl-cimigenol(8),25-dehydrocimigenol(9),cimigenol-3-O-β-D-xyloside(10)were isolated and identified.
    CONCLUSIONS:
    Compounds 2,3,4 were isolated from C.dahurica for the first time.