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    Dihydrocinchonamine
    Dihydrocinchonamine
    Information
    CAS No. 10283-68-8 Price
    Catalog No.CFN99043Purity>=98%
    Molecular Weight298.4 Type of CompoundAlkaloids
    FormulaC19H26N2OPhysical DescriptionPowder
    Download Manual    COA    MSDSSimilar structuralComparison (Web)
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    Description: Reference standards.
    Dihydrocinchonamine Description
    Source: The aerial parts of Ophiorrhiza major Ridl.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Cell. 2018 Jan 11;172(1-2):249-261.e12.
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    IF=36.216(2019)

    PMID: 29328914

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    IF=22.415(2019)

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    IF=14.548(2019)

    PMID: 29149595

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    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
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    IF=12.804(2019)

    PMID: 30417089
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.3512 mL 16.756 mL 33.5121 mL 67.0241 mL 83.7802 mL
    5 mM 0.6702 mL 3.3512 mL 6.7024 mL 13.4048 mL 16.756 mL
    10 mM 0.3351 mL 1.6756 mL 3.3512 mL 6.7024 mL 8.378 mL
    50 mM 0.067 mL 0.3351 mL 0.6702 mL 1.3405 mL 1.6756 mL
    100 mM 0.0335 mL 0.1676 mL 0.3351 mL 0.6702 mL 0.8378 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    The Alkaloids: Chemistry and Physiology Volume 11, 1968, Pages 73–77
    Chapter 3 The 2,2′-Indolylquinuclidine Alkaloids[Reference: WebLink]
    The group of 2,2′-indolylquinuclidine alkaloids has a narrow distribution and only two members have been discovered in the past few years. This chapter focuses on accepted stereochemistry, although an unequivocal proof is still required for C-3 in cinchonamine.
    METHODS AND RESULTS:
    The course of the acetylation of cinchonamine has been restudied using the parent base, Dihydrocinchonamine and O-tritylcinchonamine. Many of the compounds formed in this investigation were amorphous, but were satisfactorily characterized via thin-layer chromatography and mass spectrometry, along with UV- and IR-measurements. At low temperatures (dry ice-acetone), cinchonamine yields O-acetylcinchonamine. Dihydrocinchonamine behaves analogously upon treatment with acetic anhydride, although there are difficulties because of the amorphous nature of the products.
    CONCLUSIONS:
    Cinchophyllamine contains two 5-methoxyindole nuclei with unsubstituted nitrogen atoms, a vinyl group, and two basic nitrogens of which one is tertiary and the other secondary. A reinvestigation of the alkaloid content of the leaves of Cinchona legeriana Moens gives, besides quinamine, two new bases analyzing for C31H36N4O2—cinchophyllamine and isocinchophyllamine.