ChemFaces is a professional high-purity natural products manufacturer.
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1. Reference standards
2. Pharmacological research
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More articles cited ChemFaces products.
Int J Biol Macromol. 2018 Feb 12. Ind Crops Prod.2014 Dec 1;62:173-178.FEBS Lett.2015 Jan 2;589(1):182-7. J Bone Miner Res. 2017 Jul 26.Scientific Reports2015 August 26
Universidade Estadual Paulista2017;Sci Rep. 2017 Dec 11;Industrial Crops and Products.2015, P 185-191J Biol Chem.2014 Jan 17.Phytomedicine.2018 Jan 1;
J Chromatogr A. 2017 Oct 6;Mol Med Rep.2015 Sep 21Phytomedicine. 2017 Jan 15;Int J Mol Sci.2017 Nov 30;
Our products had been exported to the following research institutions and universities, And still growing.
Almansora University (Egypt)University of Melbourne (Australia)University of Hertfordshire (United Kingdom)Mahidol University (Thailand)
Institute of Tropical Disease Un... (Indonesia)Chang Gung University (Taiwan)Charles Sturt University (Denmark)Kyushu University (Japan)
Deutsches Krebsforschungszentrum (Germany)Helmholtz Zentrum München (Germany)University of Illinois (USA)
||Phytolaccaceae has anti-tumor activity, the mechanism may be related to the capacity of Esculentoside H for TNF release.|
|Zhongguo Yao Li Xue Bao. 1993 Nov;14(6):550-2. |
|Effect of esculentoside H on release of tumor necrosis factor from mouse peritoneal macrophages.[Pubmed: 8010057]|
METHODS AND RESULTS:
Effect of Esculentoside H (EH) on release of tumor necrosis factor (TNF) from murine peritoneal macrophage (Mphi) in vitro was studied. The results showed that Esculentoside H (12.5-200 micrograms.ml-1) induced the thioglycolate-broth elicited peritoneal Mphi to release TNF into supernatants in a dose-dependent manner, and higher levels of TNF activity were detected in the supernatants from Esculentoside H-stimulated calcimycin-primed Mø culture. Esculentoside H-induced TNF release had a different type of kinetics compared with that of lipopolysaccharides (LPS). LPS-induced release of TNF increased rapidly until 6 h after LPS stimulation, then declined gradually, while Esculentoside H-induced TNF release increased gradually after Esculentoside H stimulation and reached its peak at approximately 24 h later.
These results suggested that the anti-tumor mechanisms of Phytolaccaceae may be related to the capacity of Esculentoside H for TNF release.
Esculentoside H Description
||The roots of Phytolacca acinosa Roxb.
||DMSO, Pyridine, Methanol, Ethanol, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.PMID: 29328914
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.PMID: 29149595
Scientific Reports 2017 Dec 11;7(1):17332.doi: 10.1038/s41598-017-17427-6.PMID: 29230013
Molecules. 2017 Oct 27;22(11). pii: E1829.doi: 10.3390/molecules22111829.PMID: 29077044
J Cell Biochem. 2018 Feb;119(2):2231-2239.doi: 10.1002/jcb.26385. PMID: 28857247
Phytomedicine. 2018 Feb 1;40:37-47. doi:10.1016/j.phymed.2017.12.030PMID: 29496173
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.