Science | Nature | Cell | View More
Natural Products
Glucosylvitexin
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Glucosylvitexin
Price: $100 / 20mg
CAS No.: 76135-82-5
Catalog No.: CFN99139
Molecular Formula: C27H30O15
Molecular Weight: 594.5 g/mol
Purity: >=98%
Type of Compound: Flavonoids
Physical Desc.: Yellow powder
Source: The fruits of Crataegus pinnatifida Bge.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $46.8 / In-stock
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • Korea Institute of Oriental Med... (Korea)
  • University of Oslo (Norway)
  • Institute of Bioorganic Chemist... (Poland)
  • University of Liège (Belgium)
  • Melbourne University (Australia)
  • University of Wuerzburg (Germany)
  • Universite Libre de Bruxelles (Belgium)
  • Kitasato University (Japan)
  • Uniwersytet Jagielloński w Kra... (Poland)
  • Universidad de Buenos Aires (Argentina)
  • Shanghai University of TCM (China)
  • More...
Package
Featured Products
Andrographolide

Catalog No: CFN98923
CAS No: 5508-58-7
Price: $30/20mg
Tilianin

Catalog No: CFN92764
CAS No: 4291-60-5
Price: $218/20mg
Pinocembrin

Catalog No: CFN98740
CAS No: 480-39-7
Price: $40/20mg
Deapi-platycodin D

Catalog No: CFN90472
CAS No: 78763-58-3
Price: $268/10mg
Sinapine

Catalog No: CFN00092
CAS No: 18696-26-9
Price: $88/20mg
Cryptotanshinone

Catalog No: CFN98478
CAS No: 35825-57-1
Price: $30/20mg
Mulberrin

Catalog No: CFN97085
CAS No: 62949-79-5
Price: $288/20mg
Epimedin B

Catalog No: CFN99940
CAS No: 110623-73-9
Price: $128/20mg
Forsythoside A

Catalog No: CFN99705
CAS No: 79916-77-1
Price: $50/20mg
20(S)-Ginsenoside Rh2

Catalog No: CFN99971
CAS No: 78214-33-2
Price: $40/20mg
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Glucosylvitexin can inhibit thyroid peroxidase (TPO) activity, thus it can produce goitrogenic and antithyroid effects similar to those of certain other antithyroid agents and small doses of methimazole (MMI).
In vivo:
J Clin Endocrinol Metab. 1989 Apr;68(4):707-14.
Antithyroid and goitrogenic effects of millet: role of C-glycosylflavones.[Pubmed: 2921306]
Pearl millet [Pennisetum millet (L.) leeke] is the main source of food energy for the rural poor in many areas of the semiarid tropics. Epidemiological evidence suggests that millet may play a role in the genesis of endemic goiter in these areas, and sparse experimental data in rats support this suspicion.
METHODS AND RESULTS:
This study was undertaken to determine in vivo in rats and in vitro using porcine thyroid slices and a thyroid peroxidase (TPO) assay the goitrogenic and antithyroid effects of millet diets, extracts of millet, and certain pure compounds contained therein. For use in these studies, whole grain millet was progressively dehulled to yield successively four bran and four flour fractions in which direct analyses revealed progressively lower concentrations of C-glycosylflavones. In vivo feeding of bran fraction 1, that richest in C-glycosylflavones, led to a significant increase in thyroid weight and antithyroid effects. Feeding of bran fraction 2, the next richest in C-glycosylflavones, produced similar, but less marked, changes. In vitro studies of 125I metabolism using porcine thyroid slices indicated that extracts of bran fractions 1 and 2 were most potent, producing changes similar to those produced by methimazole (MMI). At a concentration of 60 mumol/L, Glucosylvitexin, the major C-glycosylflavone present in millet, had effects comparable to those of 1 mumol/L MMI. Similarly, in studies of porcine TPO, extracts of bran fraction 1 caused pronounced (85%) inhibition of enzyme activity, and progressively less inhibition was induced by extracts of bran fractions 2, 3, and 4. Overall, the TPO-inhibiting activities of the various millet fractions closely correlated with their C-glycosylflavone concentrations. Three C-glycosylflavones present concentrations. Three C-glycosylflavones present in millet, Glucosylvitexin, glycosylorientin, and vitexin, also inhibited TPO activity. Thus, in vivo and in vitro studies revealed that millet diets rich in C-glycosylflavones produce goitrogenic and antithyroid effects similar to those of certain other antithyroid agents and small doses of MMI.
CONCLUSIONS:
We conclude that in areas of iodine deficiency in which millet is a major component of the diet, its ingestion may contribute to the genesis of endemic goiter.
Glucosylvitexin Description
Source: The fruits of Crataegus pinnatifida Bge.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Isochlorogenic acid C 4'-O-glucosi...

Catalog No: CFN95405
CAS No: N/A
Price: $413/5mg
12beta-Acetoxy-7beta-hydroxy-3,11,...

Catalog No: CFN95515
CAS No: N/A
Price: $318/5mg
Cannabisin M

Catalog No: CFN95436
CAS No: 1831134-13-4
Price: $318/5mg
Physalin O

Catalog No: CFN95097
CAS No: 120849-18-5
Price: $413/5mg
9-Hydroxy-O-senecioyl-8,9-dihydroo...

Catalog No: CFN95274
CAS No: 31456-63-0
Price: $318/5mg
Yuankanin

Catalog No: CFN95128
CAS No: 77099-20-8
Price: $318/5mg
2,3-Dehydrosilychristin

Catalog No: CFN95370
CAS No: 57499-41-9
Price: $318/5mg
Lucidenic acid D2

Catalog No: CFN95020
CAS No: 98665-16-8
Price: $268/5mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.6821 mL 8.4104 mL 16.8209 mL 33.6417 mL 42.0521 mL
5 mM 0.3364 mL 1.6821 mL 3.3642 mL 6.7283 mL 8.4104 mL
10 mM 0.1682 mL 0.841 mL 1.6821 mL 3.3642 mL 4.2052 mL
50 mM 0.0336 mL 0.1682 mL 0.3364 mL 0.6728 mL 0.841 mL
100 mM 0.0168 mL 0.0841 mL 0.1682 mL 0.3364 mL 0.4205 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Andrographolide

Catalog No: CFN98923
CAS No: 5508-58-7
Price: $30/20mg
Tilianin

Catalog No: CFN92764
CAS No: 4291-60-5
Price: $218/20mg
Pinocembrin

Catalog No: CFN98740
CAS No: 480-39-7
Price: $40/20mg
Deapi-platycodin D

Catalog No: CFN90472
CAS No: 78763-58-3
Price: $268/10mg
Sinapine

Catalog No: CFN00092
CAS No: 18696-26-9
Price: $88/20mg
Cryptotanshinone

Catalog No: CFN98478
CAS No: 35825-57-1
Price: $30/20mg
Mulberrin

Catalog No: CFN97085
CAS No: 62949-79-5
Price: $288/20mg
Epimedin B

Catalog No: CFN99940
CAS No: 110623-73-9
Price: $128/20mg
Forsythoside A

Catalog No: CFN99705
CAS No: 79916-77-1
Price: $50/20mg
20(S)-Ginsenoside Rh2

Catalog No: CFN99971
CAS No: 78214-33-2
Price: $40/20mg
Tags: buy Glucosylvitexin | Glucosylvitexin supplier | purchase Glucosylvitexin | Glucosylvitexin cost | Glucosylvitexin manufacturer | order Glucosylvitexin | Glucosylvitexin distributor