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    Isomedicarpin
    Information
    CAS No. 74560-05-7 Price
    Catalog No.CFN97226Purity>=98%
    Molecular Weight270.3 Type of CompoundFlavonoids
    FormulaC16H14O4Physical DescriptionOil
    Download     COA    MSDSSimilar structuralComparison (Web)
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    Biological Activity
    Description: Isomedicarpin is a phytoalexin.
    Isomedicarpin Description
    Source: The heartwoods of Maackia amurensis.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.

    PMID: 29328914

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.

    PMID: 29149595

    Scientific Reports 2017 Dec 11;7(1):17332.
    doi: 10.1038/s41598-017-17427-6.

    PMID: 29230013

    Molecules. 2017 Oct 27;22(11). pii: E1829.
    doi: 10.3390/molecules22111829.

    PMID: 29077044

    J Cell Biochem. 2018 Feb;119(2):2231-2239.
    doi: 10.1002/jcb.26385.

    PMID: 28857247

    Phytomedicine. 2018 Feb 1;40:37-47.
    doi:10.1016/j.phymed.2017.12.030

    PMID: 29496173
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.6996 mL 18.498 mL 36.9959 mL 73.9919 mL 92.4898 mL
    5 mM 0.7399 mL 3.6996 mL 7.3992 mL 14.7984 mL 18.498 mL
    10 mM 0.37 mL 1.8498 mL 3.6996 mL 7.3992 mL 9.249 mL
    50 mM 0.074 mL 0.37 mL 0.7399 mL 1.4798 mL 1.8498 mL
    100 mM 0.037 mL 0.185 mL 0.37 mL 0.7399 mL 0.9249 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    Biochemical Systematics and Ecology.1991; 19(6):497-506.
    Isoflavonoid phytoalexins from the fungus-inoculated leaflets of Erythrina species.[Reference: WebLink]

    METHODS AND RESULTS:
    Using the drop-diffusate technique, a total of 14 isoflavonoid phytoalexins have been variously isolated from the fungus (Helminthosporium carbonum)-inoculated leaflets of 33 Erythrina species and subspecies. These compounds have been identified as 2′-hydroxydaidzein, genistein and 2′-hydroxygenistein (all isoflavones), 2′-hydroxydihydrodaidzein and dalbergiodin (both isoflavanones), demethylvestitol and isovestitol (both isoflavans), and demethylmedicarpin, glycinol, Isomedicarpin, phaseollidin, sandwicarpin, sandwicensin and cristacarpin (all pterocarpans). Diffusates from both control (water-treated) and fungus-inoculated leaflets of E. berenices and E. macrophylla also contained the constitutive isoflavone daidzein.
    CONCLUSIONS:
    With the exception of daidzein, all the Erythrina isoflavonoids (applied level 25 μg) inhibited the growth of Cladosporium herbarum on silica gel thin-layer plates. The survey data suggest that in terms of its isoflavonoid chemistry, the genus Erythrina has a close affinity with subtribes Diocleinae-Glycininae-Phaseolinae of the tribe Phaseoleae.