ChemFaces is a professional high-purity natural products manufacturer.
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1. Reference standards
2. Pharmacological research
Citing Use of our Products
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / Inquiry||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Nat Prod Sci.2014, 20(3):182-190University of Limpopo2016, 1777Food Chem.2016, 191:81-90HortTechnology2016, 26(6):816-819Phytochem Anal.2016, 27(5):296-303Front Pharmacol.2016, 7:460Tropical J. of Pha. Research...2017...Exp Parasitol.2017, 183:160-166
Food Chem.2017, 221:1135-1144J Biochem Mol Toxicol.2017, 31(9)Appl Microbiol Biotechnol....2018...Journal of functional foods...2018...Food Chem.2018, 252:207-214Biol Pharm Bull.2018, 41(1):65-72Planta Med.2018, 84(6-07):465-474J of the Korean Society of Cosmet...2019...
Molecules.2019, 24(6):E1155Academic J of Second Military Med...2019...J Sep Sci.2019, 42(21):3352-3362Korean J of Crop Science2019, 452-458Sci Rep.2019, 9:12132J Cell Physiol.2020, 10.1002J Ethnopharmacol.2020, 249:112381
Our products had been exported to the following research institutions and universities, And still growing.
Heinrich-Heine-University Düss... (Germany)The University of Newcastle (Australia)Universidad Industrial de Santa... (Colombia)University of Melbourne (Australia)
Johannes Gutenberg University M... (Germany)FORTH-IMBB (Greece)Sapienza University of Rome (Italy)University of Maryland (USA)
University of Minnesota (USA)China Medical University (Taiwan)Institute of Pathophysiology Me... (Austria)
Related Screening Libraries
||Kulactone has cytotoxic effects, with IC₅₀ values of 5.6-21.2 ug/mL, it inhibited (ED(50) 2.5-6.2 microg/mL) the P388 cancer cell line.
|Nat Prod Res. 2016 Sep;30(17):1984-7. |
|Antimicrobial compounds from root, stem bark and seeds of Melia volkensii.[Pubmed: 26517430]|
|Three compounds, toosendanin (1), Kulactone (2) and scopoletin (3), were isolated from either the root bark and/or the stem bark of Melia volkensii. Their structures were determined on the basis of spectroscopic data generated and by comparison with data from the literature.|
METHODS AND RESULTS:
1 and 2, isolated for the first time from M. volkensii, exhibited significant (p < 0.05) activity against Escherichia coli with minimum inhibitory concentration of 12.5 μg/mL, close to that of neomycin (6.25 μg/mL). The compounds also exhibited high activity against Aspergillus niger (MIC 6.25 μg/mL compared to 2.5 μg/mL for clotrimazole). Dichloromethane and methanol seed, hexane stem bark and methanol root bark extracts exhibited activities towards Escherichia coli, Staphylococcus aureus, Aspergillus niger and Plasmodium falciparum, respectively.
Antimicrobial activity of the plant towards A. niger, P. falciparum and S. aureus is reported for the first time in the current work.
||The seeds of Melia toosendan
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|J Nat Prod. 2002 Dec;65(12):1886-91. |
|Antineoplastic agents. 489. Isolation and structures of meliastatins 1-5 and related euphane triterpenes from the tree Melia dubia.[Pubmed: 12502333 ]|
METHODS AND RESULTS:
The bark of the giant neem tree Melia dubia was found to contain 11 euphane-type triterpenes. Five new compounds, meliastatins 1-5 (1-5), proved to inhibit growth of the P388 lymphocytic leukemia cell line (ED(50) 1.7-5.6 microg/mL). Four of the others, the previously known methyl kulonate (8), kulinone (9), 16-hydroxybutyrospermol (10), and Kulactone (11), were also found to inhibit (ED(50) 2.5-6.2 microg/mL) the P388 cancer cell line. In addition, two new euphane triterpenes were isolated and named dubione A (6) and dubione B (7).
Structures for each of the 11 euphane triterpenes were established by spectral techniques that included HRMS and 2D NMR.