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Sitsirikine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Sitsirikine
Price:
CAS No.: 1245-00-7
Catalog No.: CFN96218
Molecular Formula: C21H26N2O3
Molecular Weight: 354.5 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The herbs of Catharanthus roseus
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Sitsirikine is a natural product from Catharanthus roseus.
Sitsirikine Description
Source: The herbs of Catharanthus roseus
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.8209 mL 14.1044 mL 28.2087 mL 56.4175 mL 70.5219 mL
5 mM 0.5642 mL 2.8209 mL 5.6417 mL 11.2835 mL 14.1044 mL
10 mM 0.2821 mL 1.4104 mL 2.8209 mL 5.6417 mL 7.0522 mL
50 mM 0.0564 mL 0.2821 mL 0.5642 mL 1.1283 mL 1.4104 mL
100 mM 0.0282 mL 0.141 mL 0.2821 mL 0.5642 mL 0.7052 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Helvetica Chimica Acta, 2015 , 98 (10) :1381-6.
A Novel Alkaloid from Aspidosperma pyricollum (Apocynaceae) and Complete 1 H and 13 C Chemical Shift Assignments[Reference: WebLink]

METHODS AND RESULTS:
A novel natural product indole, alkaloid, named rel-pyricolluminol (1), was isolated from Aspidosperma pyricollum Müll.Arg. together with six known metabolites Sitsirikine (2), aparicin (3), ulein (4), stemmadenine (5), lupeol (6), and (3β)-sitoster-3-yl β-D-glucopyranoside (7).
CONCLUSIONS:
These compounds were characterized on the basis of their spectral data, mainly 1D- (1H,13C-DEPTQ) and 2D-NMR (1H,1H-COSY, NOESY, HSQC, and HMBC), and mass spectra (EI-MS and HR-ES-MS), involving also comparison with data from the literature.
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Andrographolide

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