Natural Products
Alpinia officinarum Hance
Alpinia officinarum, known as lesser galangal, is a plant in the ginger family, cultivated in Southeast Asia. It originated in China, where its name ultimately derives. It can grow several feet high, with long leaves and reddish-white flowers. The rhizomes, known as galangal, are valued for their spicy flavor and aromatic scent.
The 80% aqueous acetone extract from the rhizomes of Alpiniaofficinarum, a Chinese medicinal herb, were found to inhibit melanogenesis in theophylline-stimulated murine B16 melanoma 4A5 cells. Among the constituents isolated, four diarylheptanoids [5-hydroxy-1,7-diphenyl-3-heptanone, 7-(4″-hydroxy-3″-methoxyphenyl)-1-phenylhept-4-en-3-one, 5-hydroxy-7-(4″-hydroxy-3″-methoxyphenyl)-1-phenyl-3-heptanone, and 3,5-dihydroxy-1,7-diphenylheptane] and two flavonol constituents (kaempferide and galangin) inhibited melanogenesis with IC50 values of 10–48 μM, and several structural requirements of the active constituents for the inhibition were clarified.
Research products of Alpinia officinarum Hance
Catalog | Product Name | CAS Number | Manual |
---|---|---|---|
CFN98918 | Galangin | 548-83-4 | |
CFN99272 | Quercetin | 117-39-5 | |
CFN98850 | Quercitrin | 522-12-3 | |
CFN98838 | Kaempferol | 520-18-3 | |
CFN98686 | Curcumin | 458-37-7 | |
CFN98782 | Kaempferide | 491-54-3 | |
CFN98735 | Isorhamnetin | 480-19-3 | |
CFN99540 | Dihydrocurcumin | 76474-56-1 | |
CFN98489 | Alpinetin | 36052-37-6 | |
CFN97032 | 2-Hydroxy-1,8-cineole | 60761-00-4 | |
CFN99175 | Eugenol | 97-53-0 | |
CFN97724 | Rhamnocitrin | 569-92-6 | |
CFN92776 | Galangin 3-methyl ether | 6665-74-3 | |
CFN92687 | Officinaruminane B | 1246282-67-6 | n/a |
CFN92684 | (R)-5-Hydroxy-1,7-diphenyl-3-heptanone | 100761-20-4 | n/a |
CFN92686 | Alpinoid D | 1041740-13-9 | n/a |
CFN92685 | 1,7-Diphenyl-4-hepten-3-one | 79559-59-4 | n/a |
CFN96231 | 3,4-Dimethoxycinnamyl alcohol | 40918-90-9 | n/a |
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