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Natural Products
Alpinia officinarum Hance
Alpinia officinarum, known as lesser galangal, is a plant in the ginger family, cultivated in Southeast Asia. It originated in China, where its name ultimately derives. It can grow several feet high, with long leaves and reddish-white flowers. The rhizomes, known as galangal, are valued for their spicy flavor and aromatic scent.
The 80% aqueous acetone extract from the rhizomes of Alpiniaofficinarum, a Chinese medicinal herb, were found to inhibit melanogenesis in theophylline-stimulated murine B16 melanoma 4A5 cells. Among the constituents isolated, four diarylheptanoids [5-hydroxy-1,7-diphenyl-3-heptanone, 7-(4″-hydroxy-3″-methoxyphenyl)-1-phenylhept-4-en-3-one, 5-hydroxy-7-(4″-hydroxy-3″-methoxyphenyl)-1-phenyl-3-heptanone, and 3,5-dihydroxy-1,7-diphenylheptane] and two flavonol constituents (kaempferide and galangin) inhibited melanogenesis with IC50 values of 10–48 μM, and several structural requirements of the active constituents for the inhibition were clarified.
Alpinia officinarum Hance
Research products of Alpinia officinarum Hance
Catalog Product Name CAS Number Manual
CFN98918Galangin548-83-4  PDF
CFN99272Quercetin117-39-5  PDF
CFN98850Quercitrin522-12-3  PDF
CFN98838Kaempferol520-18-3  PDF
CFN98686Curcumin458-37-7  PDF
CFN98782Kaempferide491-54-3  PDF
CFN98735Isorhamnetin480-19-3  PDF
CFN99540Dihydrocurcumin76474-56-1  PDF
CFN98489Alpinetin36052-37-6  PDF
CFN970322-Hydroxy-1,8-cineole60761-00-4  PDF
CFN99175Eugenol97-53-0  PDF
CFN97724Rhamnocitrin569-92-6  PDF
CFN92776Galangin 3-methyl ether6665-74-3  PDF
CFN92687Officinaruminane B1246282-67-6  n/a
CFN92684(R)-5-Hydroxy-1,7-diphenyl-3-heptanone100761-20-4  n/a
CFN92686Alpinoid D1041740-13-9  n/a
CFN926851,7-Diphenyl-4-hepten-3-one79559-59-4  n/a
CFN962313,4-Dimethoxycinnamyl alcohol40918-90-9  n/a
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