| Structure Identification: |
| Zhongguo Zhong Yao Za Zhi. 2013 May;38(10):1548-51. | | Chemical constituents from twigs and leaves of Melodinus hemsleyanus.[Pubmed: 23947135] | To study the chemical constituents in the twigs and leaves of Melodinus hemsleyanus.
METHODS AND RESULTS:
The chemical constituents were isolated by silica gel, ODS and Sephadex LH-20 column chromatographies. Their structures were determined by chemical and spectroscopic methods. Fourteen compounds were isolated from the 95% ethanol extract of the twigs and leaves of M. hemsleyanus. Their structures were identified as 11-Hydroxytabersonine (1), venalstonid (2), sandine (3), oleanolic acid (4), ursolic acid (5), betulin (6), (+)-pinoresinol (7), (-)-syringaresinol (8), 8-hydroxypinoresinol (9), (-)-latifolin (10), cirsilineol (11), loganin (12), dibutylterephthalate (13), and beta-sitosterol (14).
CONCLUSIONS:
Compounds 4-14 were obtained from this plant for the first time. | | Planta Med. 1988 Aug;54(4):315-7. | | Study on the Alkaloids of Melodinus tenuicaudatus.[Pubmed: 17265274] |
METHODS AND RESULTS:
Fourteen alkaloids were isolated from the stem bark of MELODINUS TENUICAUDATUS Tsiang et P. T. Li. Eleven of them were identified as known alkaloids, namely, scandine ( 2), Delta (14)-eburnamine ( 4), vindolinine N(b)-oxide ( 5), 11-methoxytabersonine ( 6), vindolinine ( 7), EPI-vindolinine N(b)-oxide ( 8), hazuntine ( 9), compactinervine ( 10), 11-Hydroxytabersonine ( 11), Delta (14)-vincine ( 12), and normacusine B ( 14).
CONCLUSIONS:
Two alkaloids were new: 10-hydroxyscandine ( 1), and the dimer, tenuicausine ( 3); their structures were elucidated by spectroscopic and chemical methods. One alkaloid ( 13) occurring in trace amounts, could not be identified. |
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