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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / Inquiry||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Sci. Rep.2015, 14-23Int J Mol Sci.2017, 19(1)Molecules.2017, 22(3)Int J Biol Macromol.2018, 112:1093-1103Korean Journal of Pharmacognosy...2018...Pharmacognosy Journal...2019...Front Aging Neurosci.2019, 11:230Nutrients.2019, 12(1):E40
Nat Prod Sci.2019, 25(3):238J of the Korean Society of Food S...2019...Phytother Res.2019, 33(4):1104-1113Srinagarind Medical Journal2019, 34(1)Korean Journal of Pharmacognosy....2019...Pharmaceutical Chemistry Journal...2019...Appl. Sci.2020, 10,1304Advances in Traditional Medicine...2020...
BioResources J.2020, 15(3).J Agric Food Chem....2020...Plants (Basel).2020, 9(11):1555.Antioxidants (Basel).2020, 9(6):526.Nature Ecology & Evolution...2020...J Formos Med Assoc....2020...Molecules2021, 26(1),230
Our products had been exported to the following research institutions and universities, And still growing.
Shanghai Institute of Organic C... (China)University of Vigo (Spain)Anna University (India)Yale University (USA)
Northeast Normal University Cha... (China)Institute of Tropical Disease U... (Indonesia)University of Toulouse (France)University of Lodz (Poland)
Shanghai Institute of Biochemis... (China)Amity University (India)Uniwersytet Jagielloński w Kra... (Poland)
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1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
South African J of Plant&Soil2018, 29-32J Nat Med.2018, 72(3):734-744J Chromatogr Sci.2020, 58(6):485-493.J of L. Chroma.&Related Tech2017, 252-258J of Ana. Chem.2019, 74(11):1113-1121Eur J Pharmacol.2018, 832:96-103Food Engineering Progress2019, 23(3)209-216Nat Prod Communications2018, 10.1177Industrial Crops and Products2019, 140:111612Biomed Chromatogr.2019, 8:e4774
Related Screening Libraries
||2β,3β,23α-Trihydroxy-12-oleanen-28-oic acid shows cytotoxic activities to human lung adenocarcinoma(A-549)cell lines. 2α,3β,23-Trihydroxyolean-12-en-28-oic acid and 2α,3β,23-trihydroxyurs-12-en-28-oic acid exhibit cytotoxicity in vitro against the growth of human cancer cells lines HepG-2,with IC50 values of 16.13 ± 3.83, 15.97 ± 2.47 uM, respectively.|
|Lishizhen Medicine & Materia Medica Research, 2008,19(8):1931-2. |
|Triterpenes from Glochidion coccineum and their Cytotoxicity in Vitro[Reference: WebLink]|
|To study the chemical constituents of Glochidion coccineum and their cytotoxicity in vitro.|
METHODS AND RESULTS:
Various column chromatographic technologies were applied for isolation and purification and the structures were elucidated by spectral evidence.MTT method was applied to investigate their cytotoxic activities. Six compounds were isolated from the part of ethyl acetate and identified as Glochidiol ①,Lup-20(29)-ene-1α,23-diol ②,Glochidone ③,Epi-lupeol ④,3β,19α,23α-trihydroxy-12-oleanen-28-oic acid ⑤,2β,3β,23α-trihydroxy-12-oleanen-28-oic acid(2,3,23-Trihydroxy-12-oleanen-28-oic acid ) ⑥.
The above compounds were obtained from this plant for the first time;compounds 1~4 showed cytotoxic activities to human hepatoma(BEL-7402),as well as compounds 5 and 6 to lung adenocarcinoma(A-549)cell lines.
|Molecules. 2015 Oct 22;20(10):19252-62. |
|Cytotoxicity of Triterpenes from Green Walnut Husks of Juglans mandshurica Maxim in HepG-2 Cancer Cells.[Pubmed: 26506336 ]|
|Among the classes of identified natural products, triterpenoids, one of the largest families, have been studied extensively for their diverse structures and variety of biological activities, including antitumor effects.
METHODS AND RESULTS:
In the present study, a phytochemical study of the green walnut husks of Juglans mandshurica Maxim led to the isolation of a new dammarane triterpene, 12β, 20(R), 24(R)-trihydroxydammar-25-en-3-one (6), together with sixteen known compounds, chiefly from chloroform and ethyl acetate extracts. According to their structural characteristics, these compounds were divided into dammarane-type, oleanane- and ursane-type. Dammarane-type triterpenoids were isolated for the first time from the Juglans genus. As part of our continuing search for biologically active compounds from this plant, all of these compounds were also evaluated for their cytotoxic activities against the growth of human cancer cells lines HepG-2 by the MTT assay.
The results were shown that 20(S)-protopanaxadiol, 2α,3β,23-trihydroxyolean-12-en-28-oic acid (2,3,23-Trihydroxy-12-oleanen-28-oic acid ) and 2α,3β,23-trihydroxyurs-12-en-28-oic acid exhibited better cytotoxicity in vitro with IC50 values of 10.32±1.13, 16.13±3.83, 15.97±2.47 μM, respectively. Preliminary structure-activity relationships for these compounds were discussed.
2,3,23-Trihydroxy-12-oleanen-28-oic acid Description
||The leaves and roots of Camptotheca acuminata Decaisne
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.