2,3-dihydrosciadopitysin | CAS:34421-19-7

2,3-dihydrosciadopitysin

Citing Use of our Products

How to Order

Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Sent to Email: info@chemfaces.com

Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Fax: (0086)-27-84254680
E-mail: manager@chemfaces.com
Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC

Delivery time

Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal & Western Union

* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.

According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.

Size /Price /Stock	10 mM * 1 mL in DMSO / Inquiry
Other Packaging	*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap

Featured Products

More...

Salvianolic acid B

Catalog No: CFN99332
CAS No: 115939-25-8
Price: $50/20mg

Decuroside I

Catalog No: CFN95004
CAS No: 96638-79-8
Price: $318/5mg

Kumatakenin

Catalog No: CFN98423
CAS No: 3301-49-3
Price: $238/10mg

Chlorogenic acid

Catalog No: CFN99116
CAS No: 327-97-9
Price: $30/20mg

Desmethoxy yangonin

Catalog No: CFN90149
CAS No: 15345-89-8
Price: $188/20mg

Scopolin

Catalog No: CFN98887
CAS No: 531-44-2
Price: $80/20mg

Niranthin

Catalog No: CFN98798
CAS No: 50656-77-4
Price: $318/5mg

Description:

Standard reference

In vitro:

Chem Pharm Bull (Tokyo). 2007 May;55(5):757-61.

New constituent from Podocarpus macrophyllus var. macrophyllus shows anti-tyrosinase effect and regulates tyrosinase-related proteins and mRNA in human epidermal melanocytes.[Pubmed: 17473463]

A new biflavonoid, 2,3-dihydro-4',4'''-di-O-methylamentoflavone (5), and five known compounds, (-)-catechin (1), quercetin (2), 2,3-dihydrosciadopitysin (3), sciadopitysin (4), and isoginkgetin (6), were isolated from Podocarpus macrophyllus var. macrophyllus (Podocarpaceae). These compounds were evaluated their ability to inhibit cellular tyrosinase activity and for their melanin inhibitory activity in human epidermal melanocytes (HEMn).
METHODS AND RESULTS:
In the melanin synthesis assay, 2,3-dihydro-4',4'''-di-O-methylamentoflavone (5) showed a potent anti-tyrosinase effect with IC(50)=0.098 mM in HEMn. It also significantly decreased both protein and mRNA levels of the tyrosinase-related protein-2 (TRP-2) by Western blot and quantitative real-time PCR (qRT-PCR) analysis.
CONCLUSIONS:
These findings suggest that the new compound, 2,3-dihydro-4',4'''-di-O-methylamentoflavone (5), is the most active component of P. macrophyllus var. macrophyllus in inhibiting pigmentation and that this inhibition is exerted through inhibition of transcription of the genes encoding TRP2.

Z Naturforsch C. 2003 Jan-Feb;58(1-2):65-9.

Antifungal activity of biflavones from Taxus baccata and Ginkgo biloba.[Pubmed: 12622229]

Bilobetin and 4'''-O-methylamentoflavone were isolated and identified in the needles of Taxus baccata, for the first time in this species.
METHODS AND RESULTS:
The antifungal activity of biflavones from T. baccata and Ginkgo biloba, namely amentoflavone, 7-O-methylamentoflavone, bilobetin, ginkgetin, sciadopitysin and 2,3-dihydrosciadopitysin towards the fungi Alternaria alternata, Fusarium culmorum, Cladosporium oxysporum was determined employing computer-aided image analysis couplet to a microscope.
CONCLUSIONS:
Bilobetin exhibited a significant antifungal activity with values of ED50 14, 11 and 17 microM respectively. This compound completely inhibited the growth of germinating tubes of Cladosporium oxysporum and Fusarium culmorum at a concentration 100 microM. Activity of ginkgetin and 7-O-methylamentoflavone towards Alternaria alternata was stronger than that of bilobetin. Moreover, slight structural changes in the cell wall of Alternaria alternata exposed to ginkgetin at concentration of 200 microM were observed.

2,3-dihydrosciadopitysin Description

Source:	The hertwoods of Podocarpus macrophyllus
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

More...

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089

CAS No.	34421-19-7	Price
Catalog No.	CFN96134	Purity	>=98%
Molecular Weight	582.6	Type of Compound	Flavonoids
Formula	C₃₃H₂₆O₁₀	Physical Description	Yellow powder
Download	COA MSDS SDF	Similar structural	Comparison (Web) (SDF)

Product Name	2,3-dihydrosciadopitysin
CAS No.:	34421-19-7
Catalog No.:	CFN96134
Molecular Formula:	C₃₃H₂₆O₁₀
Molecular Weight:	582.6 g/mol
Purity:	>=98%
Type of Compound:	Flavonoids
Physical Desc.:	Yellow powder
Source:	The hertwoods of Podocarpus macrophyllus
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:
Download:	COA MSDS SDF
Similar structural:	Comparison (Web) (SDF)

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Flavonoids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	1.7164 mL	8.5822 mL	17.1644 mL	34.3289 mL	42.9111 mL
5 mM	0.3433 mL	1.7164 mL	3.4329 mL	6.8658 mL	8.5822 mL
10 mM	0.1716 mL	0.8582 mL	1.7164 mL	3.4329 mL	4.2911 mL
50 mM	0.0343 mL	0.1716 mL	0.3433 mL	0.6866 mL	0.8582 mL
100 mM	0.0172 mL	0.0858 mL	0.1716 mL	0.3433 mL	0.4291 mL

CFN70356	Cupressuflavone	3952-18-9	538.5	C₃₀H₁₈O₁₀
CFN97224	4',4'''-Di-O-methylcupressuflavone	74336-91-7	566.5	C₃₂H₂₂O₁₀
CFN95007	8,8''-Bibaicalein	135309-02-3	538.5	C₃₀H₁₈O₁₀
CFN96555	Acuminatanol	948884-38-6	638.49	C₃₀H₂₂O₁₆
CFN96163	2,3-Dihydroamentoflavone 7,4'-dimethyl ether	873999-88-3	568.5	C₃₂H₂₄O₁₀
CFN96119	2,3-Dihydroheveaflavone	110382-42-8	582.6	C₃₃H₂₆O₁₀
CFN96134	2,3-dihydrosciadopitysin	34421-19-7	582.6	C₃₃H₂₆O₁₀
CFN96378	2,3-Dihydropodocarpusflavone A	852875-96-8	554.5	C₃₁H₂₂O₁₀
CFN98755	Tetrahydroamentoflavone	48236-96-0	542.5	C₃₀H₂₂O₁₀
CFN95558	3',3'''-Binaringenin	145399-99-1	542.5	C₃₀H₂₂O₁₀