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    Natural Products
    Acetylepipodophyllotoxin
    Information
    CAS No. 1180-35-4 Price
    Catalog No.CFN99279Purity>=98%
    Molecular Weight456.5 Type of CompoundLignans
    FormulaC24H24O9Physical DescriptionPowder
    Download Manual    COA    MSDS    SDFSimilar structuralComparison (Web)  (SDF)
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    Acetylepipodophyllotoxin

    Acetylepipodophyllotoxin
    Product Name Acetylepipodophyllotoxin
    CAS No.: 1180-35-4
    Catalog No.: CFN99279
    Molecular Formula: C24H24O9
    Molecular Weight: 456.5 g/mol
    Purity: >=98%
    Type of Compound: Lignans
    Physical Desc.: Powder
    Source: The roots of Dysosma versipellis (Hance) M.Cheng ex Ying
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
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  • RSC Adv.2018, 32621-32636
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  • Biological Activity
    Description: Acetylepipodophyllotoxin has insecticidal activity.
    In vitro:
    Journal of Northwest Sci-Tech Univ of Agr and Forest., 2007, 35(9):117-22.
    Study on 6 insecticidal podophyllotoxin compounds from the berries of Sabina vulgaris Ant.[Reference: WebLink]

    METHODS AND RESULTS:
    In order to isolate other insecticidal podophyllotoxin compounds from the berries of Sabina vulgaris Ant.,six podophyllotoxin compounds were isolated by tracing with insecticidal activity. They were identified as acetyl picropodophyllotoxin,deoxypicropodophyllotoxin, Acetylepipodophyllotoxin,podophyllotoxin,deoxypodophyllotoxin and picropodophyllotoxin.The antifeeding activities against the 3rd-instar larve of Mythimna separate W.and the toxic activities against the 4th-instar larvae of Pieris rapae L.and the 3rd-instar larve of Plutella xylostella L.were tested by leaf-disk method and leaf-dipping method,respectively.
    CONCLUSIONS:
    The bioassay results indicated that all these compounds showed highly antifeeding and toxic activities against the 3 tested insects.Podophyllotoxin and deoxypodophyllotoxin were the two with the highest insecticidal activities among the six,while picropodophyllotoxin was the lowest.Besides,acetyl picropodophyllotoxin,deoxypicropodophyllotoxin,Acetylepipodophyllotoxin and picropodophyllotoxin were insecticidal compounds firstly reported from S.vulgaris.
    Acetylepipodophyllotoxin Description
    Source: The roots of Dysosma versipellis (Hance) M.Cheng ex Ying
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.1906 mL 10.9529 mL 21.9058 mL 43.8116 mL 54.7645 mL
    5 mM 0.4381 mL 2.1906 mL 4.3812 mL 8.7623 mL 10.9529 mL
    10 mM 0.2191 mL 1.0953 mL 2.1906 mL 4.3812 mL 5.4765 mL
    50 mM 0.0438 mL 0.2191 mL 0.4381 mL 0.8762 mL 1.0953 mL
    100 mM 0.0219 mL 0.1095 mL 0.2191 mL 0.4381 mL 0.5476 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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