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    Natural Products
    Angelol M
    Angelol M
    Information
    CAS No. 1092952-64-1 Price $288 / 5mg
    Catalog No.CFN95060Purity>=98%
    Molecular Weight376.4Type of CompoundCoumarins
    FormulaC20H24O7Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)  (SDF)
    Citing Use of our Products
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    Tel: (0086)-27-84237683
    Fax: (0086)-27-84254680
    E-mail: manager@chemfaces.com
    Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
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    2. We accept: Wire transfer & Credit card & Paypal & Western Union
    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / $244.8 / In-stock
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
    Our products had been exported to the following research institutions and universities, And still growing.
  • University of Medicine and Phar... (Romania)
  • University of Illinois (USA)
  • Institute of Chinese Materia Me... (China)
  • Universidad de Buenos Aires (Argentina)
  • Cancer Research Initatives Foun... (Malaysia)
  • Aarhus University (Denmark)
  • University of British Columbia (Canada)
  • Universit?t Basel (Switzerland)
  • Fraunhofer-Institut für Moleku... (Germany)
  • Utah State University (USA)
  • Complutense University of Madrid (Spain)
  • More...
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    Angelol M

    Angelol M
    Product Name Angelol M
    CAS No.: 1092952-64-1
    Catalog No.: CFN95060
    Molecular Formula: C20H24O7
    Molecular Weight: 376.4 g/mol
    Purity: >=98%
    Type of Compound: Coumarins
    Physical Desc.: Powder
    Source: The roots of Angelica sinensis
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Price: $288 / 5mg
    Inquire / Order: manager@chemfaces.com
    Technical Inquiries: service@chemfaces.com
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    1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
  • Semyung University2017, 149407
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  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
  • Coumarins Compound Library
  • Biological Activity
    Description: Angelol M shows activity in inhibiting prostate specific antigen (PSA) secreted from androgen dependent prostate cancer cell line, LNCaP cells.
    In vitro:
    Chem Pharm Bull (Tokyo). 2008 Sep;56(9):1338-41.
    Coumarins from campylotropis hirtella (FRANCH.) SCHINDL. and their inhibitory activity on prostate specific antigen secreted from LNCaP cells.[Pubmed: 18758115]
    Campylotropis hirtella (FRANCH.) SCHINDL. was used as a folk medicine for the treatment of benign prostate hyperplasia (BPH) in China.
    METHODS AND RESULTS:
    In this study, two new coumarins, 7,2',4'-trihydroxy-5-methoxy-3-arylcoumarin (1), 6-[(1S,2S)-2-angeloyloxy-1,3-dihydroxy-3-methylbutyl]-7-methoxycoumarin, named Angelol M (2), together with eleven known related compounds (3-13) were isolated from this plant under the bioassay guided fractionation.
    CONCLUSIONS:
    All the compounds showed activity with different levels in inhibiting prostate specific antigen (PSA) secreted from androgen dependent prostate cancer cell line, LNCaP cells, using ELISA method.
    Angelol M Description
    Source: The roots of Angelica sinensis
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.6567 mL 13.2837 mL 26.5675 mL 53.135 mL 66.4187 mL
    5 mM 0.5313 mL 2.6567 mL 5.3135 mL 10.627 mL 13.2837 mL
    10 mM 0.2657 mL 1.3284 mL 2.6567 mL 5.3135 mL 6.6419 mL
    50 mM 0.0531 mL 0.2657 mL 0.5313 mL 1.0627 mL 1.3284 mL
    100 mM 0.0266 mL 0.1328 mL 0.2657 mL 0.5313 mL 0.6642 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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