Angelol M | CAS:1092952-64-1 | Manufacturer ChemFaces

Angelol M

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Size /Price /Stock	10 mM * 1 mL in DMSO / $175.7 / In-stock
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Description:

Angelol M shows activity in inhibiting prostate specific antigen (PSA) secreted from androgen dependent prostate cancer cell line, LNCaP cells.

In vitro:

Chem Pharm Bull (Tokyo). 2008 Sep;56(9):1338-41.

Coumarins from campylotropis hirtella (FRANCH.) SCHINDL. and their inhibitory activity on prostate specific antigen secreted from LNCaP cells.[Pubmed: 18758115]

Campylotropis hirtella (FRANCH.) SCHINDL. was used as a folk medicine for the treatment of benign prostate hyperplasia (BPH) in China.
METHODS AND RESULTS:
In this study, two new coumarins, 7,2',4'-trihydroxy-5-methoxy-3-arylcoumarin (1), 6-[(1S,2S)-2-angeloyloxy-1,3-dihydroxy-3-methylbutyl]-7-methoxycoumarin, named Angelol M (2), together with eleven known related compounds (3-13) were isolated from this plant under the bioassay guided fractionation.
CONCLUSIONS:
All the compounds showed activity with different levels in inhibiting prostate specific antigen (PSA) secreted from androgen dependent prostate cancer cell line, LNCaP cells, using ELISA method.

Angelol M Description

Source:	The roots of Angelica sinensis
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Angelol M
Price:	$318 / 10mg
CAS No.:	1092952-64-1
Catalog No.:	CFN95060
Molecular Formula:	C₂₀H₂₄O₇
Molecular Weight:	376.4 g/mol
Purity:	>=98%
Type of Compound:	Coumarins
Physical Desc.:	Powder
Source:	The roots of Angelica sinensis
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Coumarins Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.6567 mL	13.2837 mL	26.5675 mL	53.135 mL	66.4187 mL
5 mM	0.5313 mL	2.6567 mL	5.3135 mL	10.627 mL	13.2837 mL
10 mM	0.2657 mL	1.3284 mL	2.6567 mL	5.3135 mL	6.6419 mL
50 mM	0.0531 mL	0.2657 mL	0.5313 mL	1.0627 mL	1.3284 mL
100 mM	0.0266 mL	0.1328 mL	0.2657 mL	0.5313 mL	0.6642 mL

CFN89250	Hopeyhopin	63975-56-4	274.27	C₁₅H₁₄O₅
CFN96622	Thamnosmonin	60094-90-8	276.28	C₁₅H₁₆O₅
CFN99738	Peucedanol	28095-18-3	278.30	C₁₅H₁₈O₅
CFN89411	Peucedanol 3'-O-glucoside	65891-61-4	426.41	C₂₀H₂₆O₁₀
CFN89412	Peucedanol 7-O-glucoside	65853-04-5	426.41	C₂₀H₂₆O₁₀
CFN93412	Peujaponiside	155740-16-2	558.5	C₂₅H₃₄O₁₄
CFN90999	Angelol A	19625-17-3	376.4	C₂₀H₂₄O₇
CFN95060	Angelol M	1092952-64-1	376.4	C₂₀H₂₄O₇
CFN91000	Angelol B	83156-04-1	376.4	C₂₀H₂₄O₇
CFN95971	Angelol E	83156-03-0	378.4	C₂₀H₂₆O₇