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    Natural Products
    Quercetin-3-o-rutinose
    Information
    CAS No. 949926-49-2 Price
    Catalog No.CFN92447Purity>=98%
    Molecular Weight610.5Type of CompoundFlavonoids
    FormulaC27H30O16Physical DescriptionYellow powder
    Download Manual    COA    MSDS    SDFSimilar structuralComparison (Web)  (SDF)
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    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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    Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
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  • Biological Activity
    Description: Quercetin-3-o-rutinose has antioxidative activity, it exerts strong DPPH radical-scavenging activity.
    In vitro:
    Phytomedicine. 2003;10(6-7):544-51.
    Study on the inhibitory effects of Korean medicinal plants and their main compounds on the 1,1-diphenyl-2-picrylhydrazyl radical.[Pubmed: 13678241]

    METHODS AND RESULTS:
    The polyphenols isolated from these plants, procyanidin B-3, (+)-catechin, gallic acid, methyl gallate, quercetin, quercetin-3-O-beta-D-glucoside, quercetin-3-O-beta-galactoside, Quercetin-3-o-rutinose and kaempferol, exerted strong DPPH radical-scavenging activity.
    CONCLUSIONS:
    These results suggest that the Korean medicinal plants and the polyphenols isolated from them that exhibited effective radical-scavenging activity may be promising agents for scavenging free radicals and treating diseases associated with excess free radicals.
    Am J Chin Med. 2003;31(6):907-17.
    The inhibitory effects of 12 medicinal plants and their component compounds on lipid peroxidation.[Pubmed: 14992543]
    The antioxidative activities of 12 medicinal plants and the compounds isolated from them were investigated using the thiocyanate method to evaluate inhibitory effects on lipid peroxidation in the linoleic acid system.
    METHODS AND RESULTS:
    The peroxide levels gradually increased during incubation in the presence of linoleic acid over 3 days, and most of the plants inhibited lipid peroxidation. In particular, of the plants tested, Cudrania tricuspidata, Zanthoxylum piperitum, Houttuynia cordata and Ulmus parvifolia reduced lipid peroxidation more effectively as lipid peroxidation progressed, resulting in inhibition of about 80% relative to the control value by the 3rd day of incubation. In addition, the polyphenols isolated from the plants also showed marked and dose-dependent inhibitory effects on lipid peroxidation. The compounds with the strongest activities were 3,4-dihydroxylbenzoic acid, quercetin, the quercetin glycosides quercetin-3-O-beta-D-galactoside, quercetin-3-O-alpha-L-rhamnoside, quercetin-3-O-beta-D-glucoside and Quercetin-3-o-rutinose, catechin, gallic acid, methyl gallate and rosamultin isolated from Zanthoxylum piperitum, Houttuynia cordata, Rosa rugosa and Cedrela sinensis. Moreover, quercetin glycosides showed stronger activity than quercetin, suggesting that glycosylation increases the antioxidative activity of quercetin.
    CONCLUSIONS:
    Our results indicate that the medicinal plants and their polyphenols show promise as therapeutic agents for various disorders involving free radical reactions.
    Quercetin-3-o-rutinose Description
    Source: The herbs of Callicarpa bodinieri Levl.
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
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    IF=36.216(2019)

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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.638 mL 8.19 mL 16.38 mL 32.76 mL 40.95 mL
    5 mM 0.3276 mL 1.638 mL 3.276 mL 6.552 mL 8.19 mL
    10 mM 0.1638 mL 0.819 mL 1.638 mL 3.276 mL 4.095 mL
    50 mM 0.0328 mL 0.1638 mL 0.3276 mL 0.6552 mL 0.819 mL
    100 mM 0.0164 mL 0.0819 mL 0.1638 mL 0.3276 mL 0.4095 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    J Pharm Biomed Anal. 1994 Mar;12(3):325-34.
    Electrochemistry of catechol-containing flavonoids.[Pubmed: 8031931]
    The electrochemical properties of four structurally related flavonoids, quercetin, quercetin-3-O-rhamnose (quercitrin), Quercetin-3-o-rutinose (rutin) and luteolin were investigated. These flavonoids were shown to undergo homogenous chemical reactions following oxidation at a glassy carbon electrode.
    METHODS AND RESULTS:
    These reactions were studied using cyclic voltammetry and rotating ring-disk voltammetry. Both first-order and zero-order processes were observed. The rate of the zero-order process was strongly dependent on the substituent at the C-3 position of the flavonoid. The rate of the first-order process was independent of substitution. Two products were observed using liquid chromatography.
    CONCLUSIONS:
    These products did not correspond to previously reported products of enzymatic oxidation. The products were not stable under conditions for isolation.