Bayogenin | CAS:6989-24-8 | Manufacturer ChemFaces

Bayogenin

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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.

According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.

Size /Price /Stock	10 mM * 1 mL in DMSO / $75.2 / In-stock
Other Packaging	*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap

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Bayogenin Description

Source:	The tubers of Bolbostemma paniculatum
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Kinase Assay:

《Chinese Journal of Natural Medicines》 2010-06

Synthesis and Biological Evaluation of Arjunolic Acid, Bayogenin, Hederagonic Acid and 4-Epi-hederagonic Acid as Glycogen Phosphorylase Inhibitors[Reference: WebLink]

To study glycogen phosphorylase inhibitory activity of natural pentacyclic triterpenes bearing 23-hydroxy or 24-hydroxy.
METHODS AND RESULTS:
Arjunolic acid, Bayogenin, hederagonic acid and 4-epi-hederagonic acid were synthesized from oleanolic acid as the starting material and biologically evaluated as glycogen phosphorylase inhibitors. Arjunolic acid, Bayogenin, hederagonic acid and 4-epi-hederagonic acid were successfully semi-synthesized by multiple steps. The synthesis of arjunolic acid was via 11 steps in about 10% overall yield, and Bayogenin via 14 steps in about 12% overall yield. Biological evaluation indicated that arjunolic acid, Bayogenin, hederagonic acid and 4-epi-hederagonic acid showed moderate potency of glycogen phosphorylase inhibition with IC50 of 53-103 μmol/L.
CONCLUSIONS:
Arjunolic acid, Bayogenin, hederagonic acid and 4-epi-hederagonic acid are gly-cogen phosphorylase inhibitors with moderate potency. Insert of 23-hydroxy or 24-hydroxy to oleanane skeleton has a tendency to be unfavorable to GP inhibition.

Product Name	Bayogenin
Price:	$288 / 20mg
CAS No.:	6989-24-8
Catalog No.:	CFN90314
Molecular Formula:	C₃₀H₄₈O₅
Molecular Weight:	488.70 g/mol
Purity:	>=98%
Type of Compound:	Triterpenoids
Physical Desc.:	Powder
Source:	The tubers of Bolbostemma paniculatum
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Inhibitors Compound Library Triterpenoids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.0462 mL	10.2312 mL	20.4625 mL	40.9249 mL	51.1561 mL
5 mM	0.4092 mL	2.0462 mL	4.0925 mL	8.185 mL	10.2312 mL
10 mM	0.2046 mL	1.0231 mL	2.0462 mL	4.0925 mL	5.1156 mL
50 mM	0.0409 mL	0.2046 mL	0.4092 mL	0.8185 mL	1.0231 mL
100 mM	0.0205 mL	0.1023 mL	0.2046 mL	0.4092 mL	0.5116 mL

CFN92210	3-beta-O-(trans-p-Coumaroyl)maslinic acid	35482-91-8	618.9	C₃₉H₅₄O₆
CFN92208	3-beta-O-(cis-p-Coumaroyl)maslinic acid	69297-40-1	618.9	C₃₉H₅₄O₆
CFN92275	Eucalyptolic acid	189272-68-2	648.9	C₄₀H₅₆O₇
CFN96017	Camaldulenic acid	71850-15-2	470.7	C₃₀H₄₆O₄
CFN98397	Arjunic acid	31298-06-3	488.7	C₃₀H₄₈O₅
CFN98690	Arjunolic acid	465-00-9	488.7	C₃₀H₄₈O₅
CFN95039	Arjungenin	58880-25-4	504.7	C₃₀H₄₈O₆
CFN96829	3-O-Coumaroylarjunolic acid	171864-20-3	634.85	C₃₉H₅₄O₇
CFN98310	2,3-Dihydroxy-12-oleanen-28-oic acid	26563-68-8	472.7	C₃₀H₄₈O₄
CFN99041	2,3,23-Trihydroxy-12-oleanen-28-oic acid	102519-34-6	488.7	C₃₀H₄₈O₅