Science | Nature | Cell | View More
Natural Products
Crizotinib (PF-02341066)
Crizotinib (PF-02341066)
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Crizotinib (PF-02341066)
Price:
CAS No.: 877399-52-5
Catalog No.: CFN60054
Molecular Formula: C21H22Cl2FN5O
Molecular Weight: 450.34 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source:
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • Instituto Politécnico de Bragan?a (Portugal)
  • University of Limpopo (South Africa)
  • Donald Danforth Plant Science C... (USA)
  • University of Stirling (United Kingdom)
  • Rio de Janeiro State University (Brazil)
  • Seoul National University (Korea)
  • University of Otago (New Zealand)
  • University of East Anglia (United Kingdom)
  • Kyoto University (Japan)
  • University of Fribourg (Switzerland)
  • University of Cincinnati (USA)
  • More...
Package
Featured Products
Physalin L

Catalog No: CFN90166
CAS No: 113146-74-0
Price: $288/5mg
Secoisolariciresinol

Catalog No: CFN98363
CAS No: 29388-59-8
Price: $288/10mg
Calycosin

Catalog No: CFN99140
CAS No: 20575-57-9
Price: $80/20mg
Isorhynchophylline

Catalog No: CFN96197
CAS No: 6859-01-4
Price: $138/20mg
Plantamajoside

Catalog No: CFN99522
CAS No: 104777-68-6
Price: $100/20mg
Delphinidin-3-O-glucoside chloride

Catalog No: CFN92038
CAS No: 6906-38-3
Price: $238/10mg
Hispidulin

Catalog No: CFN99491
CAS No: 1447-88-7
Price: $218/20mg
Hydrangenol

Catalog No: CFN98745
CAS No: 480-47-7
Price: $ /
Soyasaponin Aa

Catalog No: CFN90455
CAS No: 117230-33-8
Price: $ / mg
Praeruptorin B

Catalog No: CFN98140
CAS No: 81740-07-0
Price: $148/10mg
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Crizotinib (PF-02341066) is a potent inhibitor of c-Met and ALK with IC50 of 11 nM and 24 nM in cell-based assays, respectively. It is also a potent ROS1 inhibitor with Ki value less than 0.025 nM. Crizotinib induces autophagy through inhibition of the STAT3 pathway in multiple lung cancer cell lines.
Targets: c-Met | ALK | ROS1 | Autophagy | STAT3
Crizotinib (PF-02341066) Description
Source:
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
2''-O-Galloylmyricitrin

Catalog No: CFN95046
CAS No: 56939-52-7
Price: $333/5mg
Dichotomine B

Catalog No: CFN95193
CAS No: 755036-41-0
Price: $318/5mg
Quercetin 3,7-diglucoside

Catalog No: CFN95408
CAS No: 6892-74-6
Price: $318/10mg
2-Cinnamoyl-1-galloylglucose

Catalog No: CFN95098
CAS No: 56994-83-3
Price: $338/5mg
Isovitexin-2''-O-rhamnoside (2''-O...

Catalog No: CFN95314
CAS No: 72036-50-1
Price: $318/5mg
Mucronulatol

Catalog No: CFN95386
CAS No: 20878-98-2
Price: $318/5mg
Solafuranone

Catalog No: CFN95312
CAS No: 367965-50-2
Price: $318/5mg
Ganoderic acid GS-1

Catalog No: CFN95571
CAS No: 1206781-64-7
Price: $413/5mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.2205 mL 11.1027 mL 22.2054 mL 44.4109 mL 55.5136 mL
5 mM 0.4441 mL 2.2205 mL 4.4411 mL 8.8822 mL 11.1027 mL
10 mM 0.2221 mL 1.1103 mL 2.2205 mL 4.4411 mL 5.5514 mL
50 mM 0.0444 mL 0.2221 mL 0.4441 mL 0.8882 mL 1.1103 mL
100 mM 0.0222 mL 0.111 mL 0.2221 mL 0.4441 mL 0.5551 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Physalin L

Catalog No: CFN90166
CAS No: 113146-74-0
Price: $288/5mg
Secoisolariciresinol

Catalog No: CFN98363
CAS No: 29388-59-8
Price: $288/10mg
Calycosin

Catalog No: CFN99140
CAS No: 20575-57-9
Price: $80/20mg
Isorhynchophylline

Catalog No: CFN96197
CAS No: 6859-01-4
Price: $138/20mg
Plantamajoside

Catalog No: CFN99522
CAS No: 104777-68-6
Price: $100/20mg
Delphinidin-3-O-glucoside chloride

Catalog No: CFN92038
CAS No: 6906-38-3
Price: $238/10mg
Hispidulin

Catalog No: CFN99491
CAS No: 1447-88-7
Price: $218/20mg
Hydrangenol

Catalog No: CFN98745
CAS No: 480-47-7
Price: $ /
Soyasaponin Aa

Catalog No: CFN90455
CAS No: 117230-33-8
Price: $ / mg
Praeruptorin B

Catalog No: CFN98140
CAS No: 81740-07-0
Price: $148/10mg
Tags: buy Crizotinib (PF-02341066) | Crizotinib (PF-02341066) supplier | purchase Crizotinib (PF-02341066) | Crizotinib (PF-02341066) cost | Crizotinib (PF-02341066) manufacturer | order Crizotinib (PF-02341066) | Crizotinib (PF-02341066) distributor
if" alt="payment"/>