ChemFaces is a professional high-purity natural products manufacturer.
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / Inquiry||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
FEBS Lett.2015, 589(1):182-7HortTechnology2016, 26(6):816-819J Ethnopharmacol.2017, 198:205-213J Bone Miner Res.2017, 32(12):2415-2430Front Pharmacol.2017, 8:673Nat Prod Commun.2018, 10.1177Asian Journal of Chemistry...2018...J Sci Food Agric.2018, 98(3):1153-1161
J Cancer.2019, 10(23):5843-5851Environ Toxicol.2019, 34(4):513-520.Toxicol Res.2019, 35(4):371-387Biomolecules.2019, 9(11):E696Sci Rep.2019, 9:19059Saudi Pharm J2020, 10.1016United States Patent Application...2020...Front Pharmacol.2020, 11:251.
Nutrients.2020, 12(3):595.Pharmaceuticals (Basel)....2020...Int J Mol Sci.2020, 21(9):3239.Food Chem.2020, 327:126992.Food Chem.2020, 332:127412Foods.2020, 9(10):1348. Environ Toxicol.2020, doi: 10.1002
Our products had been exported to the following research institutions and universities, And still growing.
University of Stirling (United Kingdom)University of Auckland (New Zealand)University of Lodz (Poland)Ateneo de Manila University (Philippines)
Universidad Veracuzana (Mexico)Heinrich-Heine-University Düss... (Germany)Centrum Menselijke Erfelijkheid (Belgium)Warszawski Uniwersytet Medyczny (Poland)
Universitas islam negeri Jakarta (Indonesia)Kazusa DNA Research Institute (Japan)Weizmann Institute of Science (Israel)
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1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Clin Exp Pharmacol Physiol.2020, doi: 10.1111Molecules.2020, 25(9):2081.Microb Pathog.2019, 131:128-134J Agric Food Chem.2016, 64(35):6783-90Industrial Crops and Products2020, 146:112186Plant Physiol Biochem.2019, 144:355-364Molecules.2019, 24(4):E709Molecules.2019, 24(24),4583Biochemistry.2018, 57(40):5886-5896Acta Biochim Pol.2015, 62(2):253-8
Related Screening Libraries
||Dihydroquercetin-rich extract (Lavitol) derived from the Dahurian larch tree, used as a food additive and as a dietary supplement ingredient.(+)-Dihydroquercetin has antioxidant activity, exhibits neuroprotective actions against the oxidative injuries induced in cortical cell cultures.|
|Brain Res., 2003, 965(1-2):130-6. |
|Neuroprotective effects of antioxidative flavonoids, quercetin, (+)-dihydroquercetin and quercetin 3-methyl ether, isolated from Opuntia ficus-indica var. saboten.[Pubmed: 12591129]|
|The flavonoids quercetin, (+)-dihydroquercetin, and quercetin 3-methyl ether were isolated from the ethyl acetate fractions of the fruits and stems of Opuntia ficus-indica var. saboten. |
METHODS AND RESULTS:
In the present study, we evaluated their protective effects against oxidative neuronal injuries induced in primary cultured rat cortical cells and their antioxidant activities by using three different cell-free bioassays. Quercetin was found to inhibit H(2)O(2)- or xanthine (X)/xanthine oxidase (XO)-induced oxidative neuronal cell injury, with an estimated IC(50) of 4-5 micro g/ml. However, it was no more protective at concentrations of 30 micro g/ml and above. (+)-Dihydroquercetin concentration-dependently inhibited oxidative neuronal injuries, but it was less potent than quercetin. On the other hand, quercetin 3-methyl ether potently and dramatically inhibited H(2)O(2)- and X/XO-induced neuronal injuries, with IC(50) values of 0.6 and 0.7 micro g/ml, respectively. All three principles markedly inhibited lipid peroxidation and scavenged 1,1-diphenyl-2-picrylhydrazyl free radicals. In addition, quercetin and quercetin 3-methyl ether were shown to inhibit XO activity in vitro, with respective IC(50) values of 10.67 and 42.01 micro g/ml.
These results indicate that quercetin, (+)-dihydroquercetin, and quercetin 3-methyl ether are the active antioxidant principles in the fruits and stems of Opuntia ficus-indica var. saboten exhibiting neuroprotective actions against the oxidative injuries induced in cortical cell cultures. Furthermore, quercetin 3-methyl ether appears to be the most potent neuroprotectant of the three flavonoids isolated from this plant.
| Int. J.Toxicol., 2015, 34(2): 243-310. |
|Toxicological and Genotoxicity Assessment of a Dihydroquercetin-Rich Dahurian Larch Tree (Larix gmelinii Rupr) Extract (Lavitol).[Pubmed: 25850419 ]|
|Safety assessment is reported of an orally ingested dihydroquercetin-rich extract (Lavitol) derived from the Dahurian larch tree, used as a food additive and as a dietary supplement ingredient.
METHODS AND RESULTS:
Dihydroquercetin, a potent antioxidant, is also known as taxifolin. The results of genotoxicity and toxicological tests (Comet assay, micronucleus test in human lymphocytes, chromosomal aberration test, subacute 7-day oral toxicity study, subchronic 90-day toxicology study with histopathologies, and, prenatal and postnatal developmental toxicity studies) on the extract provide further support for the safety of its consumption as a food supplement and food additive.
||The herbs of Xanthoceras sorbifolia
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.