ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
Citing Use of our Products
How to Order
Orders via your E-mail:
1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Sent to Email: firstname.lastname@example.org
Order & Inquiry & Tech Support
Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
Delivery & Payment method
1. Usually delivery time: Next day delivery by 9:00 a.m. Order now
2. We accept: Wire transfer & Credit card & Paypal & Western Union
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / Inquiry||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Korean Journal of Pharmacognosy...2014...Analytical sci. & Tech2016, 186-193Evid Based Complement Alternat Me...2016...Phytother Res.2016, 30(12):2020-2026J of the Korean Society of Food S...2016...J Agric Food Chem.2016, 64(35):6783-90Research on Crops.2017, 18(3):569The Pharmaceutical Society of Jap...2018...
Br J Pharmacol.2018, 175(6):902-923Chem Biol Interact.2018, 290:44-51Phytomedicine.2018, 47:48-57APMIS.2019, 127(10):688-695Neuropharmacology2019, 151437Int J Mol Sci.2019, 20(14):E3538Molecules.2019, 24(11):E2044Molecules.2019, 24(6):E1155
Exp Biol Med (Maywood)....2019...Pharmaceutical Chemistry Journal...2019...Crystals2020, 10(3), 206.Int J Mol Sci.2020, 21(9):3144.J Microbiol Biotechnol....2020...Antioxidants (Basel).2020, 9(11):1121.Molecules.2021, 26(2):E255.
Our products had been exported to the following research institutions and universities, And still growing.
University of Lodz (Poland)University of Liège (Belgium)Universiti Malaysia Pahang (Malaysia)Korea Intitute of Science and T... (Korea)
University of Zurich (Switzerland)University of Sao Paulo (Brazil)The Ohio State University (USA)Kyung Hee University (Korea)
Mendel University in Brno (Czech Republic)Shanghai University of TCM (China)Leibniz-Institut für Pflanzenb... (Germany)
Inquire / Order:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
University of Limpopo2016, 1777Korean Journal of Pharmacognosy2018, 49(3):270-277Bull. Pharm. Sci., Assiut University2020, 43(2):149-155.J Agric Food Chem.2018, 66(1):351-358Phytochemistry.2021, 181:112539. Chem Biol Interact.2020, 328:109200.Functional Ecology2020, doi: 10.1111.J Appl Toxicol.2020, 40(7):965-978.Evid Based Complement Alternat Med.2016, 2016:1739760Arch Biochem Biophys.2018, 644:93-99
Related Screening Libraries
|| Isoneochamaejasmin A exhibits significantly nematicidal activities against both B. xylophilus and B. mucronatus.|
Isoneochamaejasmine A Description
||The roots of Stellera chamaejasme Linn.
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|Natural Product Research & Development,2014,26(5):639-44. |
|Nematicidal Activities of Isoneochamaejasmin A and Neochamaejasmin B from the Roots of Stellera chamaejasme L.against Bursaphelenchus xylophilus and Bursaphelenchus mucronatus[Reference: WebLink]|
METHODS AND RESULTS:
Two biflavonoids were isolated from ethanol extract from the roots of Stellera chamaejasme L.,and their chemical structures were identified as Isoneochamaejasmin A(Isoneochamaejasmine A) and neochamaejasmin B by nuclear magnetic resonance spectral data. The nematicidal activities of the two compounds were tested by bioassay methods with second-stage juveniles(J2s)of Bursaphelenchus xylophilus and Bursaphelenchus mucronatus.
The results showed these two biflavonoids exhibited significantly nematicidal activities against both B. xylophilus and B. mucronatus. Neochamaejasmin B displayed better nematicidal activity than isoneochamaejasmin A against two species nematodes under the same conditions.
|Drug Metab Dispos. 2014 Apr;42(4):735-43. |
|Hepatic glucuronidation of isoneochamaejasmin a from the traditional Chinese medicine Stellera chamaejasme L. Root.[Pubmed: 24452863]|
|Isoneochamaejasmin A (Isoneochamaejasmine A, INCA), a biflavonoid, is one of main active ingredients in the dried root of Stellera chamaejasme L., a widely used traditional Chinese medicine.
METHODS AND RESULTS:
In the present study, we identified the glucuronidation metabolite of Isoneochamaejasmin A and characterized the UDP glucuronosyltransferases (UGTs) responsible for Isoneochamaejasmin A glucuronidation. 7-O-glucuronide (M1) and 4'-O-glucuronide (M2) were identified by incubation of Isoneochamaejasmin A with human liver microsomes (HLMs) in the presence of UDP glucuronic acid, and their structures were confirmed by high-resolution mass spectrometry and nuclear magnetic resonance analyses.
Although Isoneochamaejasmin A is a single enantiomer molecule, its M1 metabolite showed two equal-size peaks on a πNAP stationary phase but only one peak on a C(18) stationary phase, indicating that the 7-/7''- and 4'-/4'''-hydroxyl groups of Isoneochamaejasmin A were in different spatial configurations relative to each other.