ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
Citing Use of our Products
How to Order
Orders via your E-mail:
1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Sent to Email: firstname.lastname@example.org
Order & Inquiry & Tech Support
Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
Delivery & Payment method
1. Usually delivery time: Next day delivery by 9:00 a.m. Order now
2. We accept: Wire transfer & Credit card & Paypal & Western Union
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / Inquiry||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Pharmacogn Mag.2015, 11(43):562-6BMC Complement Altern Med....2017...Naunyn Schmiedebergs Arch Pharmac...2017...Phytochemistry Letters2017, 449-455J Agric Food Chem....2017...Korean Journal of Medicinal Crop ...2018...Front Microbiol.2019, 10:2806Int J Mol Sci.2019, 20(21):E5488
Int J Mol Sci.2019, 20(23):E6071Molecules.2019, 24(24):E4536Food Chem.2019, 290:286-294Food and Chemical Toxicology...2020...Cell Metab.2020, S1550-4131(20)30002-4Metabolites.2020, 10(12):497.Appl. Sci.2020, 10(20), 7323.Food Analytical Methods...2020...
Drug Des Devel Ther.2020, 14:969-976.Int J Mol Sci.2020, 21(24):9369.Bioorg Med Chem.2020, 28(12):115553.J Appl Toxicol.2020, 40(7):965-978.Horticulture Research2020, 7:111. Int Immunopharmacol.2020, 90:107268.Biochem Biophys Res Commun....2021...
Our products had been exported to the following research institutions and universities, And still growing.
Medizinische Universit?t Wien (Austria)University of Bordeaux (France)Molecular Biology Institute of ... (Spain)Monash University Sunway Campus (Malaysia)
Universidade de Franca (Brazil)Washington State University (USA)University of Maryland School o... (USA)Medical University of Gdansk (Poland)
Srinakharinwirot University (Thailand)Biotech R&D Institute (USA)Fraunhofer-Institut für Moleku... (Germany)
Inquire / Order:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Pak J Pharm Sci.2018, 31:311-315Front Pharmacol.2019, 10:1355Exp Neurobiol.2018, 27(3):200-209Antioxidants (Basel).2020, 9(11):1121.Eur Rev Med Pharmacol Sci.2020, 24(9):5127-5139.Nutrients.2017, 10(1)Sci Rep.2017, 7(1):3249Yakugaku Zasshi.2018, 138(4):571-579J Ethnopharmacol.2017, 206:327-336Arch Biochem Biophys.2018, 644:93-99
Related Screening Libraries
||Kaempferol tetraacetate is a potent antiplatelet agent. It exhibits significant cytotoxicity in vitro against three human cell lines HL-60, U937 and SK-MEL-1.|
|J Nat Prod. 1993 Jun;56(6):929-34. |
|Antiplatelet effects and vasorelaxing action of some constituents of Formosan plants.[Pubmed: 8350094]|
METHODS AND RESULTS:
Various xanthones as well as quercetin have been shown to exhibit antiplatelet activity. A series of anthraquinones analogues structurally related to xanthones and a series of quercetin-related compounds were tested for their antiplatelet effects.
Emodin, frangulin B, Kaempferol tetraacetate, quercetin-3-O-galactoside octaacetate, rhamnazin triacetate, and rhamnetin tetraacetate were found to be potent antiplatelet agents, and 1,8-dihydroxy-6-methoxy-3-methylanthraquinone 8-O-rhamnosyl-(1-->2)-glucoside, rhamnustrioside undecaacetate, rutin decaacetate, and quercetin-3-O-(6-O-alpha-L-arabinopyranosyl)-beta-D-galactopyranos ide decaacetate showed significant antiplatelet effects. Quercetin showed vasorelaxing action in rat thoracic aorta.
|Planta Med. 2008 Feb;74(2):171-4. |
|Cytotoxic activities of flavonoid glycoside acetates from Consolida oliveriana.[Pubmed: 18214815]|
METHODS AND RESULTS:
The flavonoids kaempferol, quercetin, trifolin, hyperoside 2''- and 6''- acetates, 7-glucotrifolin, biorobin and robinin were isolated from the aerial parts of Consolida oliveriana.
Their derivatives Kaempferol tetraacetate, quercetin pentaacetate, trifolin heptaacetate and hyperoside octaacetate exhibited significant cytotoxicity IN VITRO against three human cell lines HL-60, U937 and SK-MEL-1 while hyperoside 2''-acetate, hyperoside-6''-acetate, glucotrifolin decaacetate and heptamethyltrifolin were inactive.
Kaempferol tetraacetate Description
||The herbs of Cudrania tricuspidata
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|Beilstein J Org Chem. 2015 Feb 25;11:288-93. |
|Selective methylation of kaempferol via benzylation and deacetylation of kaempferol acetates.[Pubmed: 25815082]|
|A strategy for selective mono-, di- and tri-O-methylation of kaempferol, predominantly on the basis of selective benzylation and controllable deacetylation of kaempferol acetates, was developed.
METHODS AND RESULTS:
From the selective deacetylation and benzylation of Kaempferol tetraacetate (1), 3,4',5,-tri-O-acetylkaempferol (2) and 7-O-benzyl-3,4'5,-tri-O-acetylkaempferol (8) were obtained, respectively. By controllable deacetylation and followed selective or direct methylation of these two intermediates, eight O-methylated kaempferols were prepared with 51-77% total yields from kaempferol.