ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
Citing Use of our Products
How to Order
Orders via your E-mail:
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Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
Delivery & Payment method
1. Usually delivery time: Next day delivery by 9:00 a.m. Order now
2. We accept: Wire transfer & Credit card & Paypal & Western Union
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / $247.7 / In-stock||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Sci. Rep.2015, 14-23Phytother Res.2015, 29(7):1088-96Acta Agriculturae Scandinavica...2015...Korean Journal of Pharmacognosy....2015...Mediators Inflamm.2016, 2016:7216912Acta horticulturae2017, 1158:257-268Plant Methods.2017, 13:108Research on Crops.2017, 18(2)
J Food Compos Anal2017, 62:197-204J Pharm Biomed Anal.2018, 151:32-41Mol Cells.2018, 41(8):771-780Biochem Biophys Res Commun....2018...Food Engineering Progress...2019...Food Chem.2019, 278:683-691J Funct Foods2019, 54:449-456Process Biochemistry2019, 85:106-115
Pharmaceuticals (Basel)....2020...BMC Complement Med Ther. ...2020...Int J Mol Sci.2020, 21(9):3392. Horticulture Research2020, 7:111. Phytomedicine.2020, 79, 153351J of Food Quality2020, 8851285.Molecules.2021, 26(2):E255.
Our products had been exported to the following research institutions and universities, And still growing.
Michigan State University (USA)Universidad Veracuzana (Mexico)National Cancer Center Research... (Japan)Fraunhofer-Institut für Moleku... (Germany)
Nanjing University of Chinese M... (China)Institute of Bioorganic Chemist... (Poland)Universidade Federal de Santa C... (Brazil)Centrum Menselijke Erfelijkheid (Belgium)
Leibniz Institute of Plant Bioc... (Germany)University of Liège (Belgium)University of Oslo (Norway)
Inquire / Order:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
J Biomed Sci.2020, 27(1):60.Arch Toxicol.2017, 91(10):3225-3245Food Res Int.2020, 128:108778Nutrients.2020, 12(12):3638.Food Chem.2019, 276:768-775Molecules.2020, 25(21):5091.J Ethnopharmacol.2017, 206:73-77J of the Korean Society of Food Science and Nutrition2016, 45(7):1017-1025Clin Transl Oncol.2019, 10.1007Chem Pharm Bull (Tokyo).2017, 65(9):826-832
Related Screening Libraries
|| Kuwanon H, and possibly kuwanon G also, are specific antagonists for the gastrin-releasing peptide (GRP) -preferring receptor and can be useful for studying the physiological and pathological role of GRP. |
|Biochem Biophys Res Commun. 1995 Aug 15;213(2):594-9. |
|Non-peptide bombesin receptor antagonists, kuwanon G and H, isolated from mulberry.[Pubmed: 7646517 ]|
METHODS AND RESULTS:
Kuwanon G and H, isolated from the methanol extract of Morus bombycis, inhibited specific binding of [125I]gastrin-releasing peptide (GRP) to GRP-preferring receptors in murine Swiss 3T3 fibroblasts with Ki values of 470 and 290 nM, respectively. Kuwanon H was one order of magnitude less potent for inhibiting [125I]bombesin binding to neuromedin B (NMB)-preferring receptors in rat esophagus membranes. This compound antagonized bombesin-induced increases in the cytosolic free calcium concentration and GRP-induced DNA synthesis in Swiss 3T3 cells.
Thus, Kuwanon H, and possibly kuwanon G also, are specific antagonists for the GRP-preferring receptor and can be useful for studying the physiological and pathological role of GRP.
Kuwanon H Description
||The root barks of Morus alba L.
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.