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L-Norleucine
L-Norleucine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name L-Norleucine
Price: $30 / 20mg
CAS No.: 327-57-1
Catalog No.: CFN70099
Molecular Formula: C6H13NO2
Molecular Weight: 131.1 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: From Coybean
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $7.0 / In-stock
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10 mM * 1 mL in DMSO / Inquiry / In-stock
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Biological Activity
Description: The unbranched norleucine residue has intermediate properties for -structure formation.
L-Norleucine Description
Source: From Coybean
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 7.6278 mL 38.1388 mL 76.2777 mL 152.5553 mL 190.6941 mL
5 mM 1.5256 mL 7.6278 mL 15.2555 mL 30.5111 mL 38.1388 mL
10 mM 0.7628 mL 3.8139 mL 7.6278 mL 15.2555 mL 19.0694 mL
50 mM 0.1526 mL 0.7628 mL 1.5256 mL 3.0511 mL 3.8139 mL
100 mM 0.0763 mL 0.3814 mL 0.7628 mL 1.5256 mL 1.9069 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Biopolymers, 2010, 16(8):1815-1826.
Conformational properties of L ‐leucine, L ‐isoleucine, and L ‐norleucine side chains in L ‐lysine copolymers.[Reference: WebLink]

METHODS AND RESULTS:
The structure inducing properties of L-leucine, L-isoleucine, and L-Norleucine residues incorporated into poly(L-lysine) were investigated by the observation of the circular dichroism of the respective random copolypeptides. The comparison involves the coil-helix transition in water/methanol mixtures, the formation of ordered structures at higher pH, and the kinetics of the -helix to -conformation transition of the leucine and norleucine copolymers induced by temperature changes at pH 10.5.
CONCLUSIONS:
The results confirm the known properties of the leucine residue, strongly supporting the -helix conformation. They also support the idea that the isoleucine residue is one of the most powerful candidates for -structure formation, and they show that the unbranched norleucine residue has intermediate properties. The results are discussed on the basis of steric and hydrophobic properties of the three side chains.
Betaine

Catalog No: CFN99546
CAS No: 107-43-7
Price: $30/20mg
2-(3,4-Dihydroxyphenyl)ethanol

Catalog No: CFN99076
CAS No: 10597-60-1
Price: $88/20mg
Santamarine

Catalog No: CFN98667
CAS No: 4290-13-5
Price: $ /
Malic acid

Catalog No: CFN90558
CAS No: 6915-15-7
Price: $30/20mg
Silybin B

Catalog No: CFN92916
CAS No: 142797-34-0
Price: $368/20mg
Sesamin

Catalog No: CFN97034
CAS No: 607-80-7
Price: $40/20mg
Grossamide

Catalog No: CFN97672
CAS No: 80510-06-1
Price: $318/5mg
(+)-Gallocatechin

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CAS No: 970-73-0
Price: $138/20mg
Gypenoside XVII

Catalog No: CFN90193
CAS No: 80321-69-3
Price: $80/20mg
Trametenolic acid

Catalog No: CFN92366
CAS No: 24160-36-9
Price: $318/10mg
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