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    Natural Products
    Methylnissolin-3-O-glucoside
    Methylnissolin-3-O-glucoside
    Information
    CAS No. 94367-42-7 Price $188 / 20mg
    Catalog No.CFN93199Purity>=98%
    Molecular Weight462.5Type of CompoundPhenols
    FormulaC23H26O10Physical DescriptionPowder
    Download Manual    COA    MSDS    SDFSimilar structuralComparison (Web)  (SDF)
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    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / $79.4 / In-stock
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
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    Related Libraries
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  • Biological Activity
    Description: (6aR,11aR)-9,10-Dimethoxypterocarpan 3-O-β-D-glucoside(Methylnissolin-3-O- glucoside) has antioxidant activity.
    In vitro:
    Chinese Pharmaceutical Journal, 2008, 43(4):256+257-259.
    Study on Scavenging Activities for Superoxide Anion Radicals and Structure-Activity Relationship of Flavonoids from Astragalus membranaceus(Fish.) Bge. var.mongholicus(Bge.) Hsiao[Reference: WebLink]
    To study the scavenging activities of the flavonoids for superoxide anion radicals from Astragalus membranaceus (Fish.) Bge. var. mongholicus (Bge.) Hsiao, and to analyze the structure-activity relationship of the compounds.
    METHODS AND RESULTS:
    The flavonoids were isolated from Astragalus membranaceus (Fish.) Bge. var. mongholicus (Bge.) Hsiao, Their antioxidant activities were compared by scavenging the superoxide anion radicals generated by the Pyrogallic acid 3-Amino-Phthalhy-drazid(Luminol)-Na2CO 3/NaHCO3 buffer (pH 10.2) system. Twelve compounds were isolated from Astragalus membranaceus (Fish.) Bge. var. mongholicus (Bge.) Hsiao, they were quercetin(I), isoquercitrin(II), rutin(III), kaempferol(IV), isorhamnetin(V), formononetin(VI), formononetin-7-O-β-D- glucoside(VII), calycosin(VIII), (3R) 8,2′-dihydroxy-7,4′- dimethoxyisoflavan(IX), 2′,4′-dimethoxy-3′-hydroxyisoflavan-6- O-β-glucopyranoside(X), (6aR,11aR) 3,9-dimethoxy-10-hydroxypterocarpan(XI) and (6aR,11aR) 9,10-dimethoxypterocarpan-3-O-β-D-glucoside(Methylnissolin-3-O-glucoside,XII). The concentration effect relationships were all logarithmic (y = alogx + b) over the range of 10%-90% of the scavenging activities. The scavenging activities of the flavonoids for superoxide anion were decided by their structures.
    CONCLUSIONS:
    The flavonoids from Astragalus membranaceus (Fish.) Bge. var. mongholicus (Bge.) Hsiao have strong scavenging activities of the superoxide anion, and they are the main antioxidants in the herb.
    Methylnissolin-3-O-glucoside Description
    Source: The herbs of Astragalus sinicus L.
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.1622 mL 10.8108 mL 21.6216 mL 43.2432 mL 54.0541 mL
    5 mM 0.4324 mL 2.1622 mL 4.3243 mL 8.6486 mL 10.8108 mL
    10 mM 0.2162 mL 1.0811 mL 2.1622 mL 4.3243 mL 5.4054 mL
    50 mM 0.0432 mL 0.2162 mL 0.4324 mL 0.8649 mL 1.0811 mL
    100 mM 0.0216 mL 0.1081 mL 0.2162 mL 0.4324 mL 0.5405 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.