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    Natural Products
    Panaxyne
    Information
    CAS No. 122855-49-6 Price
    Catalog No.CFN96202Purity>=98%
    Molecular Weight220.3Type of CompoundLipids
    FormulaC14H20O2Physical DescriptionPowder
    Download     COA    MSDS    SDFSimilar structuralComparison (Web)  (SDF)
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    Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
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    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
    Our products had been exported to the following research institutions and universities, And still growing.
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    Panaxyne

    Panaxyne
    Product Name Panaxyne
    CAS No.: 122855-49-6
    Catalog No.: CFN96202
    Molecular Formula: C14H20O2
    Molecular Weight: 220.3 g/mol
    Purity: >=98%
    Type of Compound: Lipids
    Physical Desc.: Powder
    Source: The roots of Panax ginseng
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Price:
    Inquire / Order: manager@chemfaces.com
    Technical Inquiries: service@chemfaces.com
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  • Phytochemistry Letters2017, 449-455
  • Molecules.2019, 24(10):E1930
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  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
  • Cytotoxic Compound Library
  • Biological Activity
    Description: Panaxyne shows significant and selective cytotoxicity against SK-OV-3 with ED50 value of 1.40 microM.
    In vitro:
    Arch Pharm Res. 2008 Feb;31(2):154-9.
    Polyacetylenes from the roots of cultivated-wild ginseng and their cytotoxicity in vitro.[Pubmed: 18365683]
    Column chromatographic separation of the roots of cultivated-wild ginseng (Jangnoisam) led to the isolation of seven polyacetylenes (1-7).
    METHODS AND RESULTS:
    Their structures were determined by spectroscopic methods to be panaxynol (1), ginsenoyne-A (2), panaxydol (3), 10-methoxy heptadeca-1-ene-4, 6-dyne-3, 9-diol (4) (3R, 9R, 10R)-panaxytriol (5), Panaxyne (6), and ginsenoyne-C (7). These compounds were isolated from this source for the first time. The compounds were tested for their cytotoxic activity against four human cancer cell lines (A549, SK-OV-3, SK-MEL-2, and HCT-15) in vitro using the SRB method.
    CONCLUSIONS:
    Panaxydol (3) and Panaxyne (6) showed significant and selective cytotoxicity against SK-OV-3 with ED50 values 2.93 and 1.40 microM, respectively.
    Panaxyne Description
    Source: The roots of Panax ginseng
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 4.5393 mL 22.6963 mL 45.3926 mL 90.7853 mL 113.4816 mL
    5 mM 0.9079 mL 4.5393 mL 9.0785 mL 18.1571 mL 22.6963 mL
    10 mM 0.4539 mL 2.2696 mL 4.5393 mL 9.0785 mL 11.3482 mL
    50 mM 0.0908 mL 0.4539 mL 0.9079 mL 1.8157 mL 2.2696 mL
    100 mM 0.0454 mL 0.227 mL 0.4539 mL 0.9079 mL 1.1348 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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