Info: Read More
  • Home
  • Natural Products
  • Bioactive
  • Screening Libraries
  • Hot Products
  • Plant Catalog
  • Customer Support
  • Product Use Citation
  • About Us
  • Contact Us
  • How to Order
  • Delivery time
  • Science | Nature | Cell | View More
    Natural Products
    Pluviatolide
    Pluviatolide
    Information
    CAS No. 28115-68-6 Price
    Catalog No.CFN92059Purity>=98%
    Molecular Weight356.4Type of CompoundLignans
    FormulaC20H20O6Physical DescriptionPowder
    Download     COA    MSDS    SDFSimilar structuralComparison (Web)  (SDF)
    Citing Use of our Products
    How to Order
    Orders via your E-mail:

    1. Product number / Name / CAS No.
    2. Delivery address
    3. Ordering/billing address
    4. Contact information
    Sent to Email: info@chemfaces.com
    Contact Us
    Order & Inquiry & Tech Support

    Tel: (0086)-27-84237683
    Fax: (0086)-27-84254680
    E-mail: manager@chemfaces.com
    Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
    Delivery time
    Delivery & Payment method

    1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

    2. We accept: Wire transfer & Credit card & Paypal & Western Union
    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
    Our products had been exported to the following research institutions and universities, And still growing.
  • Celltrion Chemical Research Ins... (Korea)
  • University of Malaya (Malaysia)
  • Srinakharinwirot University (Thailand)
  • Molecular Biology Institute of ... (Spain)
  • Mahidol University (Thailand)
  • Universidad de Buenos Aires (Argentina)
  • Institute of Tropical Disease U... (Indonesia)
  • Mendel University in Brno (Czech Republic)
  • University of Zurich (Switzerland)
  • Istanbul University (Turkey)
  • Agricultural Research Organizat... (Israel)
  • More...
  • Package
    Featured Products
    7-Methoxyneochamaejasmine A

    Catalog No: CFN92156
    CAS No: 402828-38-0
    Price: $433/5mg
    Tenuifolin

    Catalog No: CFN98157
    CAS No: 20183-47-5
    Price: $100/20mg
    Neochamaejasmine B

    Catalog No: CFN92152
    CAS No: 90411-12-4
    Price: $418/5mg
    Kumatakenin

    Catalog No: CFN98423
    CAS No: 3301-49-3
    Price: $238/10mg
    Xanthohumol

    Catalog No: CFN98958
    CAS No: 569-83-5
    Price: $60/20mg
    Pomolic acid

    Catalog No: CFN99433
    CAS No: 13849-91-7
    Price: $413/5mg
    6',7'-Dihydroxybergamottin

    Catalog No: CFN98307
    CAS No: 264234-05-1
    Price: $438/10mg

    Pluviatolide

    Pluviatolide
    Product Name Pluviatolide
    CAS No.: 28115-68-6
    Catalog No.: CFN92059
    Molecular Formula: C20H20O6
    Molecular Weight: 356.4 g/mol
    Purity: >=98%
    Type of Compound: Lignans
    Physical Desc.: Powder
    Targets: AChR
    Source: The herbs of Macaranga tanarius
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Price:
    Inquire / Order: manager@chemfaces.com
    Technical Inquiries: service@chemfaces.com
    Tel: +86-27-84237783
    Fax: +86-27-84254680

    Address:
    1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
  • J of the Korean Society of Cosmetics and Cosmetology2018, 399-406
  • Molecules2021, 26(1),230
  • Nutrients2020, 12(2):488
  • Metabolites.2019, 9(11):E271
  • J Funct Foods2019, 54:449-456
  • Int J Biol Macromol.2019, 126:653-661
  • Inflammation.2020, 43(5):1716-1728.
  • LWT-Food Science and Technology2017, 75:488-496
  • Pharmacognosy Journal2019, 11,6:1235-1241
  • Acta Physiologiae Plantarum2016, 38:7
  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
  • Anti-spasmodic Compound Library
  • Lignans Compound Library
  • AChR Inhibitor Library
  • Biological Activity
    Description: (-)-Pluviatolide can inhibit electrically-induced and acetylcholine-induced contraction in the isolated guinea-pig ileum.
    Targets: AChR
    In vitro:
    J Nat Prod. 2008 Jul;71(7):1167-72.
    Chemical constituents of Aristolochia constricta: antispasmodic effects of its constituents in guinea-pig ileum and isolation of a diterpeno-lignan hybrid.[Pubmed: 18570470 ]
    Twenty constituents were isolated from the n-hexane and chloroform extracts of Aristolochia constricta, a plant whose aerial parts have been used empirically in folk medicine for various purposes.
    METHODS AND RESULTS:
    The inhibitory effects of these constituents on smooth muscle contraction in isolated guinea-pig ileum were studied in order to observe their antispasmodic effects. 3,4-Dibenzyldihydrofuran-type lignans [(-)-cubebin, (-)-hinokinin, and (-)-Pluviatolide] and a kaurene-type diterpene [(-)-kaur-16-en-19-oic acid] were isolated as active principals. They inhibited electrically induced and acetylcholine-induced contraction in the isolated guinea-pig ileum. In addition, 9- O-[(-)-kaur-15-en-17-oxyl]cubebin was isolated as a new diterpeno-lignan hybrid, although this constituent did not exhibit antispasmodic activity.
    Pluviatolide Description
    Source: The herbs of Macaranga tanarius
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
    ChemFaces New Products and Compounds
    7-Neohesperidosides

    Catalog No: CFN95018
    CAS No: 28383-41-7
    Price: $288/5mg
    Corymboside

    Catalog No: CFN95292
    CAS No: 73543-87-0
    Price: $318/10mg
    Carasinol D

    Catalog No: CFN95044
    CAS No: 1072797-66-0
    Price: $333/5mg
    Oroxylin A

    Catalog No: CFN98540
    CAS No: 480-11-5
    Price: $138/20mg
    8,8''-Bibaicalein

    Catalog No: CFN95007
    CAS No: 135309-02-3
    Price: $418/5mg
    Ginsenoside F4

    Catalog No: CFN90757
    CAS No: 181225-33-2
    Price: $/mg
    Stevioside D

    Catalog No: CFN95230
    CAS No: 1310055-59-4
    Price: $463/5mg
    Hederagenin 3-O-(2-O-acetyl-alpha-...

    Catalog No: CFN95355
    CAS No: 87562-05-8
    Price: $318/10mg
    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.8058 mL 14.0292 mL 28.0584 mL 56.1167 mL 70.1459 mL
    5 mM 0.5612 mL 2.8058 mL 5.6117 mL 11.2233 mL 14.0292 mL
    10 mM 0.2806 mL 1.4029 mL 2.8058 mL 5.6117 mL 7.0146 mL
    50 mM 0.0561 mL 0.2806 mL 0.5612 mL 1.1223 mL 1.4029 mL
    100 mM 0.0281 mL 0.1403 mL 0.2806 mL 0.5612 mL 0.7015 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    Chin J Nat Med. 2015 Feb;13(2):142-4.
    Chemical constituents from Mongolian herb Syringa pinnatifolia var. alashanensis.[Pubmed: 25769897]
    Two new sesquiterpenes, innatifolone A (1) and pinnatifolone B (2), along with 6 known compounds, furostan (3), isocalamendiol (4), Pluviatolide (5), (8S,8'R,9S)-cubebin (6), 2-(4-hydroxy-3-methoxybenzyl)-3-(3,4-dimethoxybenzyl) tetrahydrofuran (7), and methyl 3-acetoxy-12-oleanen-28-oate (8), were isolated from Mongolian herb Syringa pinnatifolia.
    7-Methoxyneochamaejasmine A

    Catalog No: CFN92156
    CAS No: 402828-38-0
    Price: $433/5mg
    Tenuifolin

    Catalog No: CFN98157
    CAS No: 20183-47-5
    Price: $100/20mg
    Neochamaejasmine B

    Catalog No: CFN92152
    CAS No: 90411-12-4
    Price: $418/5mg
    Kumatakenin

    Catalog No: CFN98423
    CAS No: 3301-49-3
    Price: $238/10mg
    Xanthohumol

    Catalog No: CFN98958
    CAS No: 569-83-5
    Price: $60/20mg
    Pomolic acid

    Catalog No: CFN99433
    CAS No: 13849-91-7
    Price: $413/5mg
    6',7'-Dihydroxybergamottin

    Catalog No: CFN98307
    CAS No: 264234-05-1
    Price: $438/10mg