ChemFaces is a professional high-purity natural products manufacturer.
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1. Reference standards
2. Pharmacological research
3. Inhibitors
Citing Use of our Products
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
| Size /Price /Stock |
10 mM * 1 mL in DMSO / $287.3 / In-stock |
Other Packaging |
*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap |
More articles cited ChemFaces products.
Molecules.2019, 24(10):E1926Tropical Journal of Pharmaceutica...2021...Chemistry of Natural Compounds...2018...J Sep Sci.2018, 41(11):2488-2497J Ginseng Res.2020, 44(4):611-618.J Chromatogr B Analyt Technol Bio...2019...Phytomedicine.2020, 79, 153351Phytomedicine.2022, 100:154085.
Advances in Traditional Medicine...2020...Sci Rep.2019, 9:12132Mie University2019, 10076.Molecules.2020, 25(23):5556. Drug Des Devel Ther.2020, 14:61-71Korea Institute of Oriental Medic...2020...J Ethnopharmacol.2017, 206:73-77Journal of Physiology & Pathology...2018...
Int J Mol Sci.2021, 22(9):5012.Medicina (Kaunas).2020, 56(12):685.Sci Rep.2019, 9(1):4646Toxicol Rep.2021, 8:1131-1142. J Ethnopharmacol.2017, 198:205-213Sci Rep.2018, 8(1)Asian J Beauty Cosmetol...2019...
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Our products had been exported to the following research institutions and universities, And still growing.
Sanford Burnham Prebys Medical ... (USA)University of Fribourg (Switzerland)Universidad de La Salle (Mexico)University of Toulouse (France)
University of Malaya (Malaysia)Stanford University (USA)Centralised Purchases Unit (CPU... (India)CSIRO - Agriculture Flagship (Australia)
Kitasato University (Japan)Amity University (India)Medizinische Universit?t Wien (Austria)
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Przewaquinone A
Inquire / Order:
manager@chemfaces.com
Technical Inquiries:
service@chemfaces.com
Tel:
+86-27-84237783
Fax:
+86-27-84254680
Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
J Biochem Mol Toxicol.2021, 35(5):e22731.Biomed Pharmacother.2020, 128:110318.Drug Test Anal.2018, 10(10):1579-1589Sci Rep.2015, 5:13194Int J Mol Sci.2015, 16(1):1232-51Phytochemistry Letters2017, 449-455Hum Exp Toxicol.2022, 41:9603271221143713.Food Quality and Safety2018, 2:213-219Turkish Journal of Pharmaceutical Sciences2022, DOI: 10.4274Nutrients.2018, 10(10)
Related Screening Libraries
| Description: |
Przewaquinone A has antitumor activity. |
| In vitro: |
| Chemosphere. 2013 Oct;93(6):997-1004. | | Algicidal activity of Salvia miltiorrhiza Bung on Microcystis aeruginosa--towards identification of algicidal substance and determination of inhibition mechanism.[Pubmed: 23810520] | The present study was to isolate and identify a potent algicidal compound from extract of Salvia miltiorrhiza and study the potential inhibition mechanism on Microcystis aeruginosa.
METHODS AND RESULTS:
Column chromatography and bioassay-guided fractionation methods were carried out to yield neo-Przewaquinone A, which was identified by spectral analysis. The EC50 of neo-Przewaquinone A on M. aeruginosa were 4.68 mg L(-1). In addition, neo-Przewaquinone A showed relatively higher security on Chlorella pyrenoidosa and Scenedesmus obliquus, with the EC50 values of 14.78 and 10.37 mg L(-1), respectively. For the potential inhibition mechanisms, neo-Przewaquinone A caused M. aeruginosa cells morphologic damage or lysis, increased malondialdehyde content and decreased the soluble protein content, total antioxidant and superoxide dismutase activity, and significantly inhibited three photosynthesis-related genes (psaB, psbD, and rbcL).
CONCLUSIONS:
The results demonstrated the algicidal effect of neo-Przewaquinone A on M. aeruginosa and provided the possible inhibition mechanisms. |
|
Przewaquinone A Description
| Source: |
The roots of Salvia miltiorrhiza |
| Solvent: |
Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| Storage: |
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
|
| After receiving: |
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling. |
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
3.2216 mL |
16.1082 mL |
32.2165 mL |
64.433 mL |
80.5412 mL |
| 5 mM |
0.6443 mL |
3.2216 mL |
6.4433 mL |
12.8866 mL |
16.1082 mL |
| 10 mM |
0.3222 mL |
1.6108 mL |
3.2216 mL |
6.4433 mL |
8.0541 mL |
| 50 mM |
0.0644 mL |
0.3222 mL |
0.6443 mL |
1.2887 mL |
1.6108 mL |
| 100 mM |
0.0322 mL |
0.1611 mL |
0.3222 mL |
0.6443 mL |
0.8054 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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