Pteroside A | CAS:35910-15-7 | Manufacturer ChemFaces

Pteroside A

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Description:

Reference standards.

In vitro:

J Nat Med. 2008 Oct;62(4):452-5.

Chemical and biologically active constituents of Pteris multifida.[Pubmed: 18553125]

A new compound, 4-caffeoyl quinic acid 5-O-methyl ether (2), together with 12 known compounds--identified as (2R,3R)-pterosin L 3-O-beta-D-glucopyrannoside (3), beta-sitosterol beta-D-glucopyranoside (4), apigenin 7-O-beta-D-glucopyranoside (5), luteolin 7-O-beta-D-glucopyranoside (6), sucrose (7), caffeic acid (8), pterosin C 3-O-beta-D-glucopyranoside (9), pteroside C (10), 4,5-dicaffeoyl quinic acid (11), Pteroside A (12), wallichoside (13) and (2S)-5,7,3',5'-tetrahydroxyflavanone (14)--were isolated from Pteris multifida.
METHODS AND RESULTS:
The structure of the new compound was determined by means of physical, chemical and spectroscopic evidence. Compounds 5 and 6 were the main constituents of the plant, with yields of 0.19% and 0.16%, respectively. The cytotoxic activities of 2, 3, and 9-13 were evaluated against a human cell line (KB cells).
CONCLUSIONS:
Among the isolated compounds, pterosin C 3-O-beta-D-glucopyrannoside (9) and 4,5-dicaffeoylquinic acid (11) showed a significant selective cytotoxicity (IC(50) 2.35 and 5.38, respectively), while moderate activity was observed for compound 2 (IC(50) 12.3). The chemosystematics of Pteris species is also discussed.

Pteroside A Description

Source:	The herbs of Pteris aquilinum
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Structure Identification:

Phytochemistry. 2016 Aug;128:82-94.

Isolation and characterisation of 13 pterosins and pterosides from bracken (Pteridium aquilinum (L.) Kuhn) rhizome.[Pubmed: 27177933 ]

Systematic phytochemical investigations of the underground rhizome of Pteridium aquilinum (L.) Kuhn (Dennstaedtiaceae) afforded thirty-five pterosins and pterosides.
METHODS AND RESULTS:
By detailed analysis of one- and two-dimensional nuclear magnetic resonance spectroscopy, circular dichroism (CD) and high-resolution mass spectrometric data, thirteen previously undescribed pterosins and pterosides have been identified. Interestingly, for the first time 12-O-β-D-glucopyranoside substituted pterosins, rhedynosides C and D, and the sulfate-containing pterosin, rhedynosin H, alongside the two known compounds, histiopterosin A and (2S)-Pteroside A2, were isolated from the rhizomes of subsp. aquilinum of bracken. In addition, six-membered cyclic ether pterosins and pterosides, rhedynosin A and rhedynoside A, are the first examples of this type of pterosin-sesquiterpenoid. Additionally, the three previously reported compounds (rhedynosin I, (2S)-2-hydroxymethylpterosin E and (2S)-12-hydroxypterosin A) were obtained for the first time from plants as opposed to mammalian metabolic products. Single crystal X-ray diffraction analysis was applied to the previously undescribed compounds (2R)-rhedynoside B, (2R)-pteroside B and (2S)-pteroside K, yielding the first crystal structures for pterosides, and three known pterosins, (2S)-pterosin A, trans-pterosin C and cis-pterosin C. Rhedynosin C is the only example of the cyclic lactone pterosins with a keto group at position C-14.
CONCLUSIONS:
Six selected pterosins ((2S)-pterosin A, (2R)-pterosin B and trans-pterosin C) and associated glycosides ((2S)-Pteroside A, (2R)-pteroside B and pteroside Z) were assessed for their anti-diabetic activity using an intestinal glucose uptake assay; all were found to be inactive at 300 μM.

Product Name	Pteroside A
Price:
CAS No.:	35910-15-7
Catalog No.:	CFN80184
Molecular Formula:	C₂₁H₃₀O₈
Molecular Weight:	410.19 g/mol
Purity:	>=98%
Type of Compound:	Sesquiterpenoids
Physical Desc.:	Powder
Source:	The herbs of Pteris aquilinum
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Download:	COA MSDS
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Sesquiterpenoids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.4379 mL	12.1895 mL	24.3789 mL	48.7579 mL	60.9474 mL
5 mM	0.4876 mL	2.4379 mL	4.8758 mL	9.7516 mL	12.1895 mL
10 mM	0.2438 mL	1.2189 mL	2.4379 mL	4.8758 mL	6.0947 mL
50 mM	0.0488 mL	0.2438 mL	0.4876 mL	0.9752 mL	1.2189 mL
100 mM	0.0244 mL	0.1219 mL	0.2438 mL	0.4876 mL	0.6095 mL

CFN97251	Onitin 2'-O-glucoside	76947-60-9	410.5	C₂₁H₃₀O₈
CFN98899	Onitisin	53823-03-3	264.3	C₁₅H₂₀O₄
CFN97066	Onitisin 2'-O-glucoside	62043-53-2	426.5	C₂₁H₃₀O₉
CFN98442	Pterosin Z	34169-69-2	232.3	C₁₅H₂₀O₂
CFN80051	Pterosin A	35910-16-8	248.14	C₁₅H₂₀O₃
CFN80184	Pteroside A	35910-15-7	410.19	C₂₁H₃₀O₈
CFN98443	Pterosin D	34169-70-5	248.3	C₁₅H₂₀O₃
CFN96247	Pterolactone A	74730-10-2	260.3	C₁₅H₁₆O₄
CFN98485	Pteroside D	35943-38-5	410.5	C₂₁H₃₀O₈
CFN97608	Pterosin D 3-O-glucoside	84299-80-9	410.46	C₂₁H₃₀O₈