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Quercetin 3,5,7,3,4-pentamethyl ether
Quercetin 3,5,7,3,4-pentamethyl ether
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Quercetin 3,5,7,3,4-pentamethyl ether
Price:
CAS No.: 1247-97-8
Catalog No.: CFN70262
Molecular Formula: C20H20O7
Molecular Weight: 372.4 g/mol
Purity: >=98%
Type of Compound: Flavonoids
Physical Desc.: Powder
Source: The leaves of Talinum triangulare
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Related Screening Libraries
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10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Quercetin 3,5,7,3′,4′-pentamethylether exhibits significant vasorelaxing properties.
In vitro:
Phytomedicine,2004,11(4): 366-369.
Flavonoids from Achyrocline satureioides with relaxant effects on the smooth muscle of Guinea pig corpus cavernosum.[Reference: WebLink]

METHODS AND RESULTS:
Ethanol extract of the aerial parts of Achyrocline satureioides (Lam.) DC. (Asteraceae) showed a significant, dose dependent, relaxant effect on the smooth muscle of corpus cavernosum strips, obtained from Guinea pig (65.5 ± 4.1% of relaxation at the dose of 25.0 mg/ml). Bioassay guided fractionation of this extract furnished two flavonoids, quercetin and quercetin 3-methyl ether, with important vasorelaxing effects on the corpus cavernosum strips (79.8 ± 8.4 and 66.0 ± 4.8% of relaxation respectively at the dose of 0.075 mg/ml). Two methyl derivatives of quercetin obtained by synthesis, quercetin 3,7,3′,4′-tetramethylether and quercetin 3,5,7,3′,4′-pentamethylether(Quercetin 3,5,7,3,4-pentamethyl ether), showed similar relaxant effects at the dose of 0.075 mg/ml (86.4 ± 8.5 and 67.31 ± 1.4% of relaxation respectively).
CONCLUSIONS:
The results show that the ethanol extract of A. satureioides and the assayed compounds exhibit significant vasorelaxing properties. Additionally, it is shown that the number of methyl groups in the quercetin nucleus has no significant influence on the effectiveness of these compounds.
Quercetin 3,5,7,3,4-pentamethyl ether Description
Source: The leaves of Talinum triangulare
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Cell. 2018 Jan 11;172(1-2):249-261.e12.
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IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.6853 mL 13.4264 mL 26.8528 mL 53.7057 mL 67.1321 mL
5 mM 0.5371 mL 2.6853 mL 5.3706 mL 10.7411 mL 13.4264 mL
10 mM 0.2685 mL 1.3426 mL 2.6853 mL 5.3706 mL 6.7132 mL
50 mM 0.0537 mL 0.2685 mL 0.5371 mL 1.0741 mL 1.3426 mL
100 mM 0.0269 mL 0.1343 mL 0.2685 mL 0.5371 mL 0.6713 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Coumestrol

Catalog No: CFN96040
CAS No: 479-13-0
Price: $178/10mg
Isochlorogenic acid C

Catalog No: CFN99120
CAS No: 32451-88-0
Price: $70/20mg
Nootkatone

Catalog No: CFN98699
CAS No: 4674-50-4
Price: $40/20mg
Dimethylacrylshikonin

Catalog No: CFN90164
CAS No: 24502-79-2
Price: $138/20mg
Chrysophanol

Catalog No: CFN98751
CAS No: 481-74-3
Price: $30/20mg
Brucine

Catalog No: CFN90244
CAS No: 357-57-3
Price: $30/20mg
4-Methoxyglucobrassicin

Catalog No: CFN00505
CAS No: 83327-21-3
Price: $ / mg
Isosinensetin

Catalog No: CFN90806
CAS No: 17290-70-9
Price: $218/20mg
6-Gingerol

Catalog No: CFN99931
CAS No: 23513-14-6
Price: $50/20mg
(-)-Gallocatechin

Catalog No: CFN99137
CAS No: 3371-27-5
Price: $128/20mg
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