Raspberryketone glucoside | CAS:38963-94-9

Raspberryketone glucoside

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Description:

Raspberry ketone glucoside has lasting effects for the inhibition of melanogenesis and various melanogenic factors after the degradation in the skin.

Targets:

In vitro:

Journal of Society of Cosmetic Chemists of Japan, 2001, 35(2):120-126.

Lasting Effect of Raspberry Ketone Glucoside on Whitening.[Reference: WebLink]

Tyrosinase is well-known as a key enzyme responsible for the production of melanin in melanocytes. It is also known that inflammatory reactions such as active oxygen species and melanogenic factors in the skin are induced by UV irradiation.
METHODS AND RESULTS:
The keys to suppress melanin synthesis are considered to be not only the inhibition of tyrosinase activity but also that of inflammatory reactions. Raspberryketone glucoside (RKG) in raspberry fruit (Rubus ideaeus) had the inhibitory effect on the melanin synthesis. As a result of an investigation with the glycosides that have similar structure of RKG at its glycoside moieties and alkyl chain, the structure of RKG was found to be suitable as an inhibitory factor on melanogenesis. RKG released raspberry ketone (RK) gradually after the reaction with both homogenated and desquamated cells of the stratum corneum. In addition to the inhibitory effect of melanin synthesis, RK also showed remarkable functions such as the scavenge of nitric oxide (NO) which was considered to induce pigmentation of human skin through activation of melanogenesis and the inhibition of the inflammation-related reactions such as production of superoxide anion and lipid peroxide.
CONCLUSIONS:
These data indicated that RKG had lasting effects for the inhibition of melanogenesis and various melanogenic factors after the degradation in the skin.

Raspberryketone glucoside Description

Source:	The fruits of red raspberry (Rubus idaeus).
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Raspberryketone glucoside
Price:	$40 / 20mg
CAS No.:	38963-94-9
Catalog No.:	CFN93228
Molecular Formula:	C₁₆H₂₂O₇
Molecular Weight:	326.34 g/mol
Purity:	>=98%
Type of Compound:	Phenols
Physical Desc.:	Powder
Source:	The fruits of red raspberry (Rubus idaeus).
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS
Similar structural:	Comparison
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Phenols Compound Library NO Inhibitor Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	3.0643 mL	15.3214 mL	30.6429 mL	61.2858 mL	76.6072 mL
5 mM	0.6129 mL	3.0643 mL	6.1286 mL	12.2572 mL	15.3214 mL
10 mM	0.3064 mL	1.5321 mL	3.0643 mL	6.1286 mL	7.6607 mL
50 mM	0.0613 mL	0.3064 mL	0.6129 mL	1.2257 mL	1.5321 mL
100 mM	0.0306 mL	0.1532 mL	0.3064 mL	0.6129 mL	0.7661 mL

CFN95550	Methyl ganoderate A	105742-78-7	530.7	C₃₁H₄₆O₇
CFN99152	Glycyrrhetinic acid	471-53-4	470.64	C₃₀H₄₆O₄
CFN98698	Cryptomeridiol	4666-84-6	240.4	C₁₅H₂₈O₂
CFN98459	Palmatine	3486-67-7	352.4	C₂₁H₂₂NO₄