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Schisanwilsonin I
Schisanwilsonin I
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Product Name Schisanwilsonin I
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CAS No.: 1181216-84-1
Catalog No.: CFN98732
Molecular Formula: C28H34O9
Molecular Weight: 514.6 g/mol
Purity: >=98%
Type of Compound: Lignans
Physical Desc.: Powder
Source: The fruits of Schisandra wilsoniana
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
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Biological Activity
Description: Schisanwilsonin D, and schisantherin C show anti-HBV activity.
In vitro:
Bioorganic & Medicinal Chemistry Letters,2009,19(17):4958-4962.
Schisanwilsonins A–G and related anti-HBV lignans from the fruits of Schisandra wilsoniana.[Reference: WebLink]

METHODS AND RESULTS:
Seven new dibenzocyclooctane lignans, schisanwilsonins A–G (1–7), were isolated from the fruits of Schisandra wilsoniana, together with five known lignans (8–12). The structures of these new compounds were elucidated by spectroscopic methods including 2D-NMR techniques. The 12 lignans were tested for anti-hepatitis B virus (HBV) activity in vitro.
CONCLUSIONS:
Schisanwilsonin D (4), schisantherin C (9), deoxyschizandrin (10) and (+)-gomisin K3 (11) showed anti-HBV activity. 9 exhibited the most potent anti-HBV activity with potency against HBsAg and HBeAg secretion by 59.7% and 34.7%, respectively, at 50 μg/mL.
Schisanwilsonin I Description
Source: The fruits of Schisandra wilsoniana
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.9433 mL 9.7163 mL 19.4326 mL 38.8651 mL 48.5814 mL
5 mM 0.3887 mL 1.9433 mL 3.8865 mL 7.773 mL 9.7163 mL
10 mM 0.1943 mL 0.9716 mL 1.9433 mL 3.8865 mL 4.8581 mL
50 mM 0.0389 mL 0.1943 mL 0.3887 mL 0.7773 mL 0.9716 mL
100 mM 0.0194 mL 0.0972 mL 0.1943 mL 0.3887 mL 0.4858 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
CFN90123Gomisin G62956-48-3536.6C30H32O9
CFN94008Gomisin H66056-20-0418.5C23H30O7
CFN96618Tigloylgomisin H66069-55-4500.59C28H36O8
CFN96939Benzoylgomisin H66056-23-3522.59C30H34O8
CFN95223Schisphenin E1311376-52-9432.5C24H32O7
CFN90878Schisantherin E64917-83-5538.6C30H34O9
CFN96727Angeloylgomisin Q72561-28-5530.61C29H38O9
CFN90710Angeloylgomisin H66056-22-2500.58C28H36O8
CFN92350Schisanwilsonin H1181216-83-0536.6C30H32O9
CFN92728Kadsurin51670-40-7458.5C25H30O8
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