Torachrysone | CAS:22649-04-3 | Manufacturer ChemFaces

Torachrysone

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Description:

Torachrysone shows promising antioxidant activity. Torachrysone, toralactone , aloe-emodin, rhein and emodin show noticeable antibacterial effects on four strains of methicillin-resistant Staphylococcus aureus with a minimum inhibitory concentration of 2-64 micrograms/ml.

Targets:

Antifection

In vitro:

Chem. Pharm. Bull.(Tokyo).,1999, 47(8): 1121-7.

Phenolic constituents of Cassia seeds and antibacterial effect of some naphthalenes and anthraquinones on methicillin-resistant Staphylococcus aureus.[Pubmed: 10478467]

Thirteen phenolic glycosides including six new compounds were isolated from seeds of Cassia tora (Leguminosae).
METHODS AND RESULTS:
The structures of the new compounds, rubrofusarin triglucoside (7), nor-rubrofusarin gentiobioside (9), demethylflavasperone gentiobioside (10), Torachrysone gentiobioside (11), Torachrysone tetraglucoside (12) and Torachrysone apioglucoside (13), were elucidated on the basis of spectroscopic and chemical evidence. The effects of the phenolic glycosides, their aglycones and several other compounds structurally related to them on Escherichia coli K12, Pseudomonas aeruginosa PAO1 and some strains of Staphylococcus aureus were then examined.
CONCLUSIONS:
Among them, Torachrysone (15), toralactone (16), aloe-emodin (18), rhein (19) and emodin (20) showed noticeable antibacterial effects on four strains of methicillin-resistant Staphylococcus aureus with a minimum inhibitory concentration of 2-64 micrograms/ml. On the other hand, the phenolic compounds tested did not show strong antibacterial effects on E. coli and P. aeruginosa.

Torachrysone Description

Source:	The seeds of Cassia obtusifolia
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

More...

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089

Structure Identification:

Molecules. 2014 Aug 4;19(8):11453-64.

An unusual piceatannol dimer from Rheum austral D. Don with antioxidant activity.[Pubmed: 25093985]

METHODS AND RESULTS:
A novel dimer of piceatannol glycoside, named rheumaustralin (1) was isolated from the underground parts of the ethnomedicinal plant Rheum austral (Polygonaceae) collected from Tibet together with 17 known compounds, including rheumin (2), 2,5-dimethyl-7-hydroxychromone (3), 2,5-dimethylchromone-7-O-β-D-glucopyranoside (4), 7-hydroxy-2-(2'-hydroxypropyl)-5-methylchromone (5), Torachrysone (6) Torachrysone-8-O-β-D-glucopyranoside (7), 4-(4'-hydroxyphenyl)-2-butanone-4'-O-β-D-glucopyranoside (8), amabiloside (9), N-trans-feruloyl tyramine (10), chrysophanol (11), aloe-emodin (12), emodin (13), physcion (14), physcion-1-O-β-D-glucopyranoside (15), emodin-8-O-β-D-glucopyranoside (16), D-catechin (17) and gallic acid (18).
CONCLUSIONS:
Their structures were determined by combined spectroscopic methods and by comparison of their spectral data with those reported in literature. Compounds 1-10 were tested for their ability to scavenge 1, 1-diphenyl-2-picrylhydrazyl (DPPH) radical.

CAS No.	22649-04-3	Price
Catalog No.	CFN98224	Purity	>=98%
Molecular Weight	246.3	Type of Compound	Phenols
Formula	C₁₄H₁₄O₄	Physical Description	Yellow powder
Download	COA MSDS SDF Manual	Similar structural	Comparison (Web) (SDF)

Product Name	Torachrysone
CAS No.:	22649-04-3
Catalog No.:	CFN98224
Molecular Formula:	C₁₄H₁₄O₄
Molecular Weight:	246.3 g/mol
Purity:	>=98%
Type of Compound:	Phenols
Physical Desc.:	Yellow powder
Targets:	Antifection
Source:	The seeds of Cassia obtusifolia
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Antioxidants Compound Library Antibacterial Compound Library Phenols Compound Library Antifection Inhibitor Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	4.0601 mL	20.3004 mL	40.6009 mL	81.2018 mL	101.5022 mL
5 mM	0.812 mL	4.0601 mL	8.1202 mL	16.2404 mL	20.3004 mL
10 mM	0.406 mL	2.03 mL	4.0601 mL	8.1202 mL	10.1502 mL
50 mM	0.0812 mL	0.406 mL	0.812 mL	1.624 mL	2.03 mL
100 mM	0.0406 mL	0.203 mL	0.406 mL	0.812 mL	1.015 mL

CFN95473	Baishouwubenzophenone	115834-34-9	302.3	C₁₆H₁₄O₆
CFN96398	(Z)-3-Hydroxy-5-methoxystilbene	143207-76-5	226.3	C₁₅H₁₄O₂
CFN95330	New compound 7	N/A	226.3	C₁₅H₁₄O₂
CFN92784	Lusianthridin	87530-30-1	242.3	C₁₅H₁₄O₃
CFN92693	Coelonin	82344-82-9	242.3	C₁₅H₁₄O₃
CFN92692	Flavidinin	83925-00-2	254.3	C₁₆H₁₄O₃
CFN92691	Agrostophyllidin	178439-50-4	284.3	C₁₇H₁₆O₄
CFN92781	Phoyunnanin C	956344-38-0	482.5	C₃₀H₂₆O₆
CFN92782	Flavanthrin	120090-80-4	482.5	C₃₀H₂₆O₆
CFN95333	Diosniposide B	N/A	450.4	C₂₂H₂₆O₁₀