ChemFaces is a professional high-purity natural products manufacturer.
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1. Reference standards
2. Pharmacological research
Citing Use of our Products
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Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / Inquiry||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Chemistry of Plant Raw Materials...2019...J Separation Science & Technology...2016...Chinese Medicine2019, 14(1)Am J Chin Med.2022, 1-20.Acta Chromatographica2021, 00960.Chemistr of plant2016, 2016021195J Nat Med.2017, 71(2):380-388Evid Based Complement Alternat Me...2017...
Biol Pharm Bull.2020, 43(10):1534-1541.Elife.2021, 10:e68058. ARPN Journal of Eng.& Applied Sci...2016...Evid Based Complement Alternat Me...2017...Food and Fermentation Industries...2018...Chung Shan Medical University...2020...Molecules.2019, 24(4):E709Sains Malaysiana2022, 51(4):1143-1154
Chem Pharm Bull (Tokyo)....2019...Int J Mol Sci.2022, 23(24):16000.Antioxidants.2022, 11(4), 67.Tumour Biol.2015, 36(9):7027-34J Ginseng Res.2020, 44(4):611-618.Molecules.2021, 26(2):E255.J Biomol Struct Dyn.2022, 5;1-17.
Our products had been exported to the following research institutions and universities, And still growing.
University of Cincinnati (USA)University of Madras (India)University of Amsterdam (Netherlands)Seoul National University (Korea)
The Institute of Cancer Research (United Kingdom)Universidade Federal de Goias (... (Brazil)Korea Intitute of Science and T... (Korea)University of Maryland (USA)
Osmania University (India)Korea Food Research Institute(K... (Korea)Univerzita Karlova v Praze (Czech Republic)
Inquire / Order:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Life Sci.2022, 298:120488.Phytochem Anal.2021, 32(6):970-981.Molecules.2020, 25(3):734Biochem Biophys Res Commun.2020, 522(1):40-46Cell Rep.2022, 39(1):110643. Agronomy 2021, 11(3),502.Nutr Cancer.2022, 1-13.Int J Mol Sci.2021, 22(9):5012.Int Immunopharmacol.2021, 100:108073. J Formos Med Assoc.2020, S0929-6646(20)30425-3
Related Screening Libraries
|| 3-Hydroxy-5-methoxystilbene exhibits in vitro anti-mycobacterium activity against Mycobacterium tuberculosis H37Ra with IC50 values of 3.33 ug/mL in dormant phase and 3.33 ug/mL in active phase. |
|Nat Prod Res. 2015;29(22):2080-6 |
|A new butenolide cinnamate and other biological active chemical constituents from Polygonum glabrum.[Pubmed: 25643642 ]|
METHODS AND RESULTS:
Phytochemical investigation of the methanol extract of the aerial parts of Polygonum glabrum afforded one new natural product (-)-2-methoxy-2-butenolide-3-cinnamate (1) along with six known compounds, β-hydroxyfriedalanol (2), 3-hydroxy-5-methoxystilbene (3), (-) pinocembrin (4), sitosterol-(6'-O-palmitoyl)-3-O-β-D-glucopyranoside (5), (-) pinocembrin-5-methyl ether (6) and sitosterol-3-O-β-D-glucopyranoside (7).
Compound 1 showed promising in vitro anti-HIV-1 activity against primary isolates HIV-1(UG070) (X4, subtype D) and HIV-1(VB59) (R5, subtype C) assayed using TZM-bl cell line with IC50 in the range of 15.68-22.43 μg/mL. The extract showed TI in the range of 19.19-27.37 with IC50 in the range of 10.90-15.55 μg/mL. Compounds 1, 3 and 4 exhibited in vitro anti-mycobacterium activity against Mycobacterium tuberculosis H37Ra with IC50 values of 1.43, 3.33 and 1.11 μg/mL in dormant phase and 2.27, 3.33 and 1.21 μg/mL in active phase, respectively. Compound 4 was found to be the most active antiproliferative with IC50 values of 1.88-11.00 μg/mL against THP-1, A549, Panc-1, HeLa and MCF7 cell lines.
||The aerial parts of Polygonum glabrum.
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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