ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
Citing Use of our Products
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Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / $312.8 / In-stock||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Molecules. 2013, 18(11):14105-21Nat Prod Commun.2014, 9(5):679-82Am J Chin Med.2015, 30:1-22Tumour Biol.2015, 36(12):9385-93Oncotarget.2015, 6(31):30831-49J Drug Target.2016, 24:1-28Nat Plants.2016, 3:16205Bulletin of Health Research...2016...
Planta Med.2016, 82(13):1208-16PLoS One.2017, 12(8):e0181191Food Chem.2017, 221:1135-1144Phytomedicine.2017, 24:77-86J of L. Chroma.&Related Tech...2017...Biol Pharm Bull.2017, 40(6):797-806J Hematol Oncol.2018, 11(1):112Mol Microbiol.2019, 112(1):317-332
Biomed Pharmacother.2019, 116:108987Molecules.2019, 24(6):E1155Appl. Sci.2020, 10,1304Crystals2020, 10(3), 206.Int J Mol Med.2020, 45(5):1514-1524.Horticulturae2020, 6(4),76.Biorxiv.2020, doi: 10.1101.
Our products had been exported to the following research institutions and universities, And still growing.
Agricultural Research Organizat... (Israel)Chinese University of Hong Kong (China)Heinrich-Heine-University Düss... (Germany)Periyar University (India)
University of Toronto (Canada)Guangzhou Institutes of Biomedi... (China)University of British Columbia (Canada)Cornell University (USA)
Max-Planck-Insitut (Germany)Gyeongsang National University (Korea)University of Lodz (Poland)
Inquire / Order:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
J of L. Chroma.&Related Tech2017, 252-258Molecules.2016, 21(6)Nutr Res Pract.2020, 14(3):203-217.Evid Based Complement Alternat Med.2016, 2016:1739760J Sci Food Agric.2017, 97(5):1656-1662Molecules.2020, 25(23):5556. Pharm Biol.2017, 55(1):360-366FASEB J.2019, 33(8):9685-9694Antiviral Res.2013, 98(3):386-93Biochem Biophys Res Commun.2018, 505(4):1148-1153
Related Screening Libraries
||meso-Hannokinol and (+)-hannokinol can significantly inhibit lipopolysaccharide-induced nitric oxide production in BV2 microglial cells at concentrations ranging from 1 uM to 100 uM.|
|Planta Med. 2008 Jun;74(8):867-9. |
|Inhibitory constituents of lipopolysaccharide-induced nitric oxide production in BV2 microglia isolated from Amomum tsao-ko.[Pubmed: 18523923]|
|A methanolic extract of the fruits of AMOMUM TSAO-KO (Zingiberaceae) significantly attenuated nitric oxide production in lipopolysaccharide-simulated BV2 microglia.|
METHODS AND RESULTS:
Two new bicyclic nonanes characterized as 6,7-dihydroxy-indan-4-carbaldehyde ( 1) and 6-hydroxy-indan-4-carbaldehyde ( 2) were isolated with the eleven known compounds 6,7-dihydroxy-3,7-dimethyloct-2-enoic acid ( 3), tsaokoin ( 4), isotsaokoin ( 5), 8-oxogeraniol ( 6), P-menth-1-ene-5,6-diol ( 7), 3alpha-hydroxycarvotagenone ( 8), tsaokoarylone ( 9), 1,7-bis(4-hydroxy-3-methoxyphenyl)-4,6-heptadien-3one ( 10), (+)-hannokinol ( 11), meso-Hannokinol ( 12) and hannokinin ( 13), from the fruits of A. TSAO-KO using bioactivity-guided fractionation.
All thirteen compounds significantly inhibited lipopolysaccharide-induced nitric oxide production in BV2 microglial cells at concentrations ranging from 1 microM to 100 microM.
|Food Funct. 2014 Aug;5(8):1747-54. |
|Bioactivity evaluation of ingredients identified from the fruits of Amomum tsaoko Crevost et Lemaire, a Chinese spice.[Pubmed: 24915829]|
METHODS AND RESULTS:
In this work, a phytochemical investigation was conducted on Amomum tsaoko Crevost et Lemaire, a traditional Chinese spice. Based on spectroscopic methods including MS, (1)H-NMR, (13)C-NMR, DEPT135 and HMQC spectroscopy, eight main chemical compositions, sitosterol, daucosterol, meso-Hannokinol, quercetin, epicatechin, quercetin-7-O-β-glucoside, quercetin-3-O-β-glucoside, and catechol, were isolated and identified from A. tsaoko, among which quercetin, quercetin-7-O-β-glucoside and quercetin-3-O-β-glucoside were first found in A. tsaoko.
Their bioactivities were evaluated by the inhibitory effect on NO production in LPS-stimulated macrophage RAW 264.7 cells, the protective effect on H2O2-induced apoptosis of PC-12 cells and the DPPH radical scavenging assay.
||The fruit of Amomum tsao-ko.
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.