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Natural Products
Catalog No. Information
CFN93034 Lotusine

Lotusine has antihypertension and antibacterial activities.
CFN92766 Loureirin A

Loureirin A has an inhibitory effect on platelet activation, perhaps through an impairment of PI3K/Akt signaling. Loureirin A activates Wnt/-catenin pathway and promotes hair follicle stem cells (FSCs)-seeded tissue-engineered skin to repair skin wound.The molecular mechanism of Loureirin A and Wnt signaling pathway mediated anti- hepatic fibrosis and anti- angiogenesis may involve down- regulation the expression of Frizzled- 4,inhibiting the synthesis and secretion of α- SMA,TGF- β1and the proliferation of HSCs.
CFN98173 Loureirin B

Loureirin B, a flavonoid extracted from Dracaena cochinchinensis, is an inhibitor of plasminogen activator inhibitor-1 (PAI-1), with an IC50 of 26.10 μM; Loureirin B also inhibits KATP, the phosphorylation of ERK and JNK, and has anti-diabetic activity.Loureirin B inhibits fibroblast proliferation and extracellular matrix deposition in hypertrophic scar via TGF-β/Smad pathway, loureirin B can suppress tetrodotoxin-sensitive (TTX-S) voltage-gated sodium currents in a dose-dependent way.
CFN92858 Loureirin C

Loureirin C can inhibit the activities of thrombin in vitro effectively.
CFN99961 Lovastatin

Lovastatin is an inhibitor of HMG-CoA reductase with IC50 of 3.4 nM in a cell-free assay, has a direct cellular effect independent of a cholesterol-lowering effect and delays the onset and progression of diabetic nephropathy. It has a potential application to treat PD via antioxidant effect, and it promotes fibrosis and epithelial to mesenchymal transition, by regulating the production of CCN2 in human gingival fibroblasts.
CFN93152 L-Phenylalanine

L-Phenylalanine has antibacterial activity.
CFN90586 L-Quebrachitol

L-Quebrachitol can as a sugar substitute for diabetics. Administration of sea buckthorn juice enriched in L-quebrachitol can increase fasting insulin level in plasma and show similar effects on random blood glucose level, glucose tolerance and the pancreatic tissue as observed for pure sea buckthorn juice.
CFN99545 L-Rhamnose

L-Rhamnose may exhibit excellent sodium-glucose transporter (SGLT1 and SGLT2) inhibition activity. L-fucose and especially L-rhamnose have anticancer potential, they exert a significant suppressive effect on tumour growth.
CFN70146 L-Serine

L-Serine and glycine mediate the trophic actions of glial cells on Purkinje neurons. L-serine, and D-serine levels have been studied, since they could serve as biological markers.
CFN90457 L-Stepholidine

L-Stepholidine, which has dual actions on dopamine D1 and D2 receptors, attenuates heroin self-administration and cue-induced reinstatement. It also elicits anti-dyskinesia effects.