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11-Hydroxygelsenicine
11-Hydroxygelsenicine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 11-Hydroxygelsenicine
Price:
CAS No.: 1195760-68-9
Catalog No.: CFN97887
Molecular Formula: C19H22N2O4
Molecular Weight: 342.4 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The stems of Gelsemium elegans
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
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Biological Activity
Description: Standard reference
11-Hydroxygelsenicine Description
Source: The stems of Gelsemium elegans
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.9206 mL 14.6028 mL 29.2056 mL 58.4112 mL 73.014 mL
5 mM 0.5841 mL 2.9206 mL 5.8411 mL 11.6822 mL 14.6028 mL
10 mM 0.2921 mL 1.4603 mL 2.9206 mL 5.8411 mL 7.3014 mL
50 mM 0.0584 mL 0.2921 mL 0.5841 mL 1.1682 mL 1.4603 mL
100 mM 0.0292 mL 0.146 mL 0.2921 mL 0.5841 mL 0.7301 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Helvetica Chimica Acta. 2009 Sep;92(9):1889–1894.
Two New 11-Hydroxy-Substituted Gelsedine-Type Indole Alkaloids from the Stems of Gelsemium elegans.[Reference: WebLink]

METHODS AND RESULTS:
Two new 11-hydroxy-substituted gelsedine-type indole alkaloids, named 11,14-dihydroxygelsenicine (1) and 11-Hydroxygelsenicine (2), together with six known alkaloids, i.e., koumine, gelsemine, 14-hydroxygelsenicine, 11-hydroxyhumantenine, gelsenicine, and (19Z)-akuammidine, were isolated from the EtOH extract of the stems of Gelsemium elegansbenth. Their structures were determined mainly by means of spectroscopic analyses including HR-ESI-MS and 2D-NMR (HSQC, HMBC, 1H,1H-COSY).
CONCLUSIONS:
The configuration of 1 was confirmed by X-ray-diffraction analysis.
Liensinine

Catalog No: CFN99580
CAS No: 2586-96-1
Price: $100/20mg
Moscatin

Catalog No: CFN93148
CAS No: 108335-06-4
Price: $318/5mg
Quercetin

Catalog No: CFN99272
CAS No: 117-39-5
Price: $40/20mg
Squalene

Catalog No: CFN99208
CAS No: 111-02-4
Price: $30/20mg
Gypenoside XIII

Catalog No: CFN95239
CAS No: 80325-22-0
Price: $288/10mg
Myrcene

Catalog No: CFN70046
CAS No: 123-35-3
Price: $30/20mg
Isorhamnetin

Catalog No: CFN98735
CAS No: 480-19-3
Price: $60/20mg
Astragaloside III

Catalog No: CFN99174
CAS No: 84687-42-3
Price: $268/20mg
Isosaponarin

Catalog No: CFN90133
CAS No: 19416-87-6
Price: $318/5mg
Beta-Carotene

Catalog No: CFN98117
CAS No: 7235-40-7
Price: $40/20mg
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