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    2,3-dihydrosciadopitysin
    2,3-dihydrosciadopitysin
    Information
    CAS No. 34421-19-7 Price
    Catalog No.CFN96134Purity>=98%
    Molecular Weight582.6Type of CompoundFlavonoids
    FormulaC33H26O10Physical DescriptionYellow powder
    Download     COA    MSDSSimilar structuralComparison (Web)
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    2,3-dihydrosciadopitysin Description
    Source: The hertwoods of Podocarpus macrophyllus
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    J Cell Biochem. 2018 Feb;119(2):2231-2239.
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    Phytomedicine. 2018 Feb 1;40:37-47.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.7164 mL 8.5822 mL 17.1644 mL 34.3289 mL 42.9111 mL
    5 mM 0.3433 mL 1.7164 mL 3.4329 mL 6.8658 mL 8.5822 mL
    10 mM 0.1716 mL 0.8582 mL 1.7164 mL 3.4329 mL 4.2911 mL
    50 mM 0.0343 mL 0.1716 mL 0.3433 mL 0.6866 mL 0.8582 mL
    100 mM 0.0172 mL 0.0858 mL 0.1716 mL 0.3433 mL 0.4291 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    2,3-dihydrosciadopitysin References Information
    Citation [1]

    Chem Pharm Bull (Tokyo). 2007 May;55(5):757-61.

    New constituent from Podocarpus macrophyllus var. macrophyllus shows anti-tyrosinase effect and regulates tyrosinase-related proteins and mRNA in human epidermal melanocytes.[Pubmed: 17473463]
    A new biflavonoid, 2,3-dihydro-4',4'''-di-O-methylamentoflavone (5), and five known compounds, (-)-catechin (1), quercetin (2), 2,3-dihydrosciadopitysin (3), sciadopitysin (4), and isoginkgetin (6), were isolated from Podocarpus macrophyllus var. macrophyllus (Podocarpaceae). These compounds were evaluated their ability to inhibit cellular tyrosinase activity and for their melanin inhibitory activity in human epidermal melanocytes (HEMn).
    Citation [2]

    Z Naturforsch C. 2003 Jan-Feb;58(1-2):65-9.

    Antifungal activity of biflavones from Taxus baccata and Ginkgo biloba.[Pubmed: 12622229]
    Bilobetin and 4'''-O-methylamentoflavone were isolated and identified in the needles of Taxus baccata, for the first time in this species. The antifungal activity of biflavones from T. baccata and Ginkgo biloba, namely amentoflavone, 7-O-methylamentoflavone, bilobetin, ginkgetin, sciadopitysin and 2,3-dihydrosciadopitysin towards the fungi Alternaria alternata, Fusarium culmorum, Cladosporium oxysporum was determined employing computer-aided image analysis couplet to a microscope. Bilobetin exhibited a significant antifungal activity with values of ED50 14, 11 and 17 microM respectively. This compound completely inhibited the growth of germinating tubes of Cladosporium oxysporum and Fusarium culmorum at a concentration 100 microM. Activity of ginkgetin and 7-O-methylamentoflavone towards Alternaria alternata was stronger than that of bilobetin. Moreover, slight structural changes in the cell wall of Alternaria alternata exposed to ginkgetin at concentration of 200 microM were observed.