ChemFaces is a professional high-purity natural products manufacturer.
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1. Reference standards
2. Pharmacological research
Citing Use of our Products
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / $39.0 / In-stock||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
New Zealand J. Forestry Sci.2014, 44:17J Breast Cancer.2015, 18(2):112-118Inflammation2015, 38(1):445-55Acta Agriculturae Scandinavica...2015...Food Sci Biotechnol....2016...Phytother Res.2016, 30(12):2020-2026J.Acta Agriculturae Scandinavica...2017...Evid Based Complement Alternat Me...2018...
Phytomedicine.2018, 40:37-47Front Cell Infect Microbiol.2018, 8:292Eur J Pharmacol.2018, 832:96-103Bio-protocol2018, 9(14):e3301J Sci Food Agric.2018, 98(3):1153-1161Pharmacognosy Journal...2019...Int J Biol Macromol.2019, 126:653-661Plant Physiol Biochem.2019, 144:355-364
Toxicol Res.2019, 35(4):371-387J Sep Sci.2019, 42(21):3352-3362Phytomedicine.2019, 62:152962Comput Biol Chem.2019, 83:107096Saudi Pharm J2020, 10.1016Plos One.2020, 10.1371Food Res Int.2020, 128:108778
Our products had been exported to the following research institutions and universities, And still growing.
Leibniz-Institut für Pflanzenb... (Germany)Aveiro University (Portugal)University of Hull (United Kingdom)University of Lodz (Poland)
University of Bordeaux (France)Julius Kühn-Institut (Germany)Institute of Tropical Disease U... (Indonesia)Northeast Normal University Cha... (China)
Kyung Hee University (Korea)Tokyo Woman's Christian University (Japan)Institute of Pathophysiology Me... (Austria)
Related Screening Libraries
||Isoscopoletin possesses inhibitory activity against hepatitis B virus (HBV) replication; it also shows substantial inhibition against multi-drug resistant CEM/ADR5000 cells and human CCRF-CEM leukaemia cells, with the IC50 value is 1.6 and 4.0 microM, respectively.|
|Planta Med. 2006 Jul;72(9):862-4. |
|Activity-guided isolation of scopoletin and isoscopoletin, the inhibitory active principles towards CCRF-CEM leukaemia cells and multi-drug resistant CEM/ADR5000 cells, from Artemisia argyi.[Pubmed: 16881019]|
METHODS AND RESULTS:
The ethyl acetate extract of Artemisia argyi leaves showed substantial inhibition in a cell proliferation assay using human CCRF-CEM leukaemia cells. Bioassay-guided fractionation of the extract led to the isolation of scopoletin and Isoscopoletin as the active principles. Their IC50 values were 2.6 and 4.0 microM, respectively. Additionally the two substances were tested against the multidrug resistant subline, CEM/ADR5000 where they both showed IC50 values of 1.6 microM.
In contrast to the standard cytostatic drugs doxorubicin, vincristine, and paclitaxel, CEM/ADR5000 cells therefore did not exhibit cross-resistance to scopoletin and Isoscopoletin.
|Planta Med. 2005 Dec;71(12):1128-33. |
|Evaluation of antiviral activity of compounds isolated from Ranunculus sieboldii and Ranunculus sceleratus.[Pubmed: 16395649 ]|
METHODS AND RESULTS:
Nineteen compounds isolated from Ranunculus sieboldii and Ranunculus sceleratus were tested for inhibitory effects on hepatitis B virus (HBV) and Herpes simplex virus type-1 (HSV-1). The results showed that apigenin 4'- O- alpha-rhamnopyranoside, apigenin 7- O- beta-glucopyranosyl-4'- O- alpha-rhamnopyranoside, tricin 7- O- beta-glucopyranoside, tricin, and Isoscopoletin possessed inhibitory activity against HBV replication. Protocatechuyl aldehyde exhibited an inhibiting activity on HSV-1 replication.
It is therefore suggested that further investigations on these bioactive compounds might be needed to discover and develop new antiviral agents.
||The herbs of Paederia scandens (Lour.) Merr
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|Nat Prod Res. 2013;27(17):1542-7. |
|Machilusmarin, a new neuroprotective isocoumarin dimer from the stems of Machilus ichangensis Rehd. et Wils.[Pubmed: 23082968 ]|
|A new isocoumarin dimer, Machilusmarin (1), was isolated from the stem of Machilus ichangensis Rehd. et Wils., together with two known coumarins, scopoletin (2) and Isoscopoletin (3). |
METHODS AND RESULTS:
The structure of Machilusmarin (1) was elucidated by HRMS and NMR spectrums. Machilusmarin (1) showed significant neuroprotective activity against SH-SY5Y human neuroblastoma cells apoptosis induced by hydrogen peroxide at concentrations ranging from 0.625 to 10.0 μg mL(-1).