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    Liquidambaric lactone
    Liquidambaric lactone
    Information
    CAS No. 185051-75-6 Price $363 / 20mg
    Catalog No.CFN90155Purity>=98%
    Molecular Weight468.67Type of CompoundTriterpenoids
    FormulaC30H44O4Physical DescriptionWhite powder
    Download     COA    MSDSSimilar structuralComparison (Web)
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    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / $144.9 / In-stock
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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  • Biological Activity
    Description: Liquidambaric lactone may have inhibitory HIV-1 reverse transcriptase activity.
    Targets: HIV-1
    In vitro:
    Natural Product Research & Development, 2011 , 23 (1) :25-29.
    Roots of Lantana camara:Chemical Constituents and HIV-1 Reverse Transcriptase Inhibitory Activity[Reference: WebLink]

    METHODS AND RESULTS:
    Among the 25 fractions obtained from the alcohol extractive of the roots of Lantana camara L.(Verbenaceae) by silica gel column chromatography,three fractions demonstrated inhibitory HIV-1 reverse transcriptase activity.Furthermore,six pentacyclic triterpenes were isolated by reduced pressure column chromatography and identified as oleanonic acid(1),Liquidambaric lactone(2),lantadene A(3),lantadene B(4),oleanolic acid(5),and 25-hydroxy-oleanolic acid(6) by spectral analysis. Compounds 2 and 6 were reported firstly in the plants of Verbenaceae family,and the structure of 6 was confirmed firstly by X-ray crystallography.
    Liquidambaric lactone Description
    Source: The fruits of Liquidambar formosana Hance
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

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    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
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    IF=12.804(2019)

    PMID: 30417089
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.1337 mL 10.6685 mL 21.337 mL 42.6739 mL 53.3424 mL
    5 mM 0.4267 mL 2.1337 mL 4.2674 mL 8.5348 mL 10.6685 mL
    10 mM 0.2134 mL 1.0668 mL 2.1337 mL 4.2674 mL 5.3342 mL
    50 mM 0.0427 mL 0.2134 mL 0.4267 mL 0.8535 mL 1.0668 mL
    100 mM 0.0213 mL 0.1067 mL 0.2134 mL 0.4267 mL 0.5334 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    《ACTA PHARMACEUTICA SINICA》 1996-06
    STRUCTURE ELUCIDATION OF LIQUIDAMBARIC LACTONE[Reference: WebLink]
    A new triterpene lactone,named Liquidambaric lactone,was isolated fromLiquidambar formoana. Its structure was elucidated and characterized on the basis of IR,MS, ̄1H and ̄(13)CNMR coloc spectral data and Xray diffraction analysis.